Mr. Haycock, I consider myself well versed on steroids and how they work, but one thing that continually has me puzzled is this; if there is only one androgen receptor that all steroids bind to in order to induce growth, how come there are so many diverse effects of different synthetic steroids. Some make you [...]
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Androgen Receptors Downregulate Don’t They? Part 2
September 15, 2001 By Leave a Comment
In part 1 of this article we discussed the mistake of thinking about androgen receptors (testosterone receptors) in the same way we think of other receptors such as beta-receptors. Beta-receptors down regulate in response to beta-adrenergic stimulation whereas there is good evidence that androgen receptors increase in numbers in response to androgens. We also discussed [...]
Androgen Receptors Downregulate Don’t They? Part 1
September 15, 2001 By Leave a Comment
There is as much misinformation about steroids as there is good information had among bodybuilding enthusiasts. Go to any gym and you will hear some kid spouting off to his buddies about how steroids do this, or how they do that, or whatever. This soon starts somewhat of a pissing contest (excuse the expression) as [...]
Testosterone – The Good, the Bad, the Ugly
February 12, 2001 By Leave a Comment
One of the most infamous hormones around is Testosterone. You hear Clueless news anchors about it on the evening news. You hear about it in the gym. You even read about it in the “growing older with style” magazines. Depending on who you talk to, it is both the good, the bad, and the ugly [...]
Are Steroids Your Key to Preventing Andropause?
January 24, 2000 By Leave a Comment
Long-term suppression of leydig cell steroidogenesis prevents leydig cell aging Researchers: Chen H, Zirkin BR Division of Reproductive Biology, Department of Biochemistry and Molecular Biology, Johns Hopkins University, School of Hygiene and Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA. Source: Proc Natl Acad Sci U S A 1999 Dec 21;96(26):14877-81 Summary: Based [...]
Shooting Blanks? It May Be the Tamoxifen
January 6, 2000 By Leave a Comment
Effect of chronic administration of Tamoxifen on fertility in male bonnet monkeys (Macaca radiata). Researchers: Rao AJ, Ramachandra SG, Ramesh V, Krishnamurthy HN, Jayaraman S, Gopalakrishnan K, Juneja HS Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India. Source: Andrologia 1998 May-Jun;30(3):129-32 Summary: Administration of Tamoxifen via the Alzet pump at [...]
Oxandrolone Offers Relief to Spinal Cord Injury Patients
January 6, 2000 By Leave a Comment
Treatment with an anabolic agent is associated with improvement in respiratory function in persons with tetraplegia: A pilot study. Researchers:Spungen AM., Grimm DR., Strakhan M., Pizzolato PM., & Bauman WA. Work originated at Spinal Cord Damage Research Center, Mount Sinai School of Medicine, New York, NY; and Medicine and Spinal Cord Injury Services, Veterans Affairs [...]
Taking a Closer Look at the Muscles of Steroid Using Athletes… A Really Close Look
January 6, 2000 By Leave a Comment
Title:Effects of anabolic steroids on the muscle cells of strength-trained athletes. Researchers:Kadi F, Eriksson A, Holmner S, Thornell LE Department of Integrative Medical Biology, Umea University, Sweden. Source:Med Sci Sports Exerc 1999 Nov;31(11):1528-34 Summary: Athletes who use anabolic steroids get larger and stronger muscles. How this is reflected at the level of the muscle fibers [...]
Medical Supervision of Individuals Using Anabolic Steroids for Muscle Growth (Part 2)
January 6, 2000 By Leave a Comment
In part I of this series we discussed the effects of anabolic-androgenic steroid (AAS) use on the heart, the blood, cholesterol, and the liver. We also suggested some treatment options for the physician or health care provider. In this final installment we will discuss the side effects of the endocrine system including the testis, as well [...]
Medical Supervision of Individuals Using Anabolic Steroids for Muscle Growth (Part 1)
January 6, 2000 By Leave a Comment
Since the Anabolic Steroids Control Act of 1990 became law on November 29, 1990, physicians have struggled with the ethics of becoming involved with patients using anabolic steroids. There are serious repercussions for doctors’ accused of prescribing anabolic steroids to patients for physique augmentation. In addition, most doctors know very little about anabolic steroids and tend [...]
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