Originally Posted by rbauer
FYI777, yes, you are correct there are no studies of using them together, but separate studies both show a good effect. My original post was about managing any toxicity. So far in this thread eyesight, driving estrogen too low, and possible liver problems have been identified as potential problems. If those can be managed then it looks like either one drug, the other, or both together are a reasonable therapy for secondary hypogonadal individuals who want to improve HPTA function as best possible until a drug like Androxal (Zuclomiphene) starts being marketed.
JanSz thanks for that post, but it seems article mainly deals with efficiency of said Androxal in raising testosterone
not toxicity issues.For all we know toxicity is same as that of regular Clomid
but then you probably could use lower doses which would help in side effect reduction.
OK rbauer I see where you are coming from. In light of managing toxicity I'd say less toxic would be the arimidex
but I don't think the ari is as good for raising test
as the clo.(abreviating here). Ari increases test
via lowering total E levels whereby clo is actually a weak E thereby displacing your endogenous E thus preserving some E which as we all know is better than no E.
I recall from the studies that ari actually is not as drastic as letrozole
on E levels.
There are more options than just those two drugs.
I think cyclofenil may be better than clomid
as it has some advantages over clo.
Also raloxiphene and tormiphene should be considered as substituted for the clo. Ralox from my research has less toxicity issues than clo,but not sure about the torm.I do know it seems more effective tho and faster than clo for test
used alone (was used this way in one of Shippen's earlier books and in another book I saw clomid used alone.)HCG has a very favorable toxicity profile almost nil,no vision,liver side effects.
Sometimes(like all the time,LOL) big pharma just "invents" a new isomer so it can get a patent and make big bucks but lot of time there is no advantage to using that "new" drug.