Mr. Haycock,I consider myself well versed on steroids and how they work, but one thing that continually has me puzzled is this; if there is only one androgen receptor that all steroids bind to in order to induce growth, how come there are so many diverse effects of different synthetic steroids. Some make you bloat, others don’t. Some give you insomnia, other don’t. Some … [Read more...] about Non-Genomic Actions of Anabolic Steroid Hormones
In part 1 of this article we discussed the mistake of thinking about androgen receptors (testosterone receptors) in the same way we think of other receptors such as beta-receptors. Beta-receptors down regulate in response to beta-adrenergic stimulation whereas there is good evidence that androgen receptors increase in numbers in response to androgens. We also discussed the … [Read more...] about Androgen Receptors Downregulate Don’t They? Part 2
There is as much misinformation about steroids as there is good information had among bodybuilding enthusiasts. Go to any gym and you will hear some kid spouting off to his buddies about how steroids do this, or how they do that, or whatever. This soon starts somewhat of a pissing contest (excuse the expression) as to who knows more about steroids. It’s the same kind of … [Read more...] about Androgen Receptors Downregulate Don’t They? Part 1
One of the most infamous hormones around is Testosterone. You hear Clueless news anchors about it on the evening news. You hear about it in the gym. You even read about it in the "growing older with style" magazines. Depending on who you talk to, it is both the good, the bad, and the ugly of hormones.In bodybuilding it is hailed as the king of muscle builders. Among … [Read more...] about Testosterone – The Good, the Bad, the Ugly
Long-term suppression of leydig cell steroidogenesis prevents leydig cell aging Researchers: Chen H, Zirkin BRDivision of Reproductive Biology, Department of Biochemistry and Molecular Biology, Johns Hopkins University, School of Hygiene and Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA.Source: Proc Natl Acad Sci U S A 1999 Dec … [Read more...] about Are Steroids Your Key to Preventing Andropause?
Effect of chronic administration of Tamoxifen on fertility in male bonnet monkeys (Macaca radiata).Researchers: Rao AJ, Ramachandra SG, Ramesh V, Krishnamurthy HN, Jayaraman S, Gopalakrishnan K, Juneja HSDepartment of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, India.Source: Andrologia 1998 … [Read more...] about Shooting Blanks? It May Be the Tamoxifen