AAS, good or bad for tendon repair?

Discussion in 'Steroid Forum' started by youngBuilder, Dec 14, 2016.

  1. youngBuilder

    youngBuilder Member

    Had a partial tendon tear (70%) repaired with minor surgery few weeks ago. Was curious if AAS would actually offer any positive or negative impact with speed of recovery/healing of tendons. Anyone know? I've seen contradictory posts..
     
    ambulldog likes this.
  2. BigSky

    BigSky Member

    Steroids like testosterone slow and nearly stop collagen synthesis.
    Winstrol will cause your tendons to become stronger but much more brittle which can lead to tears l
    Some steroids like deca and eq increase collagen synthesis but not to any great degree when stacked with other steroids and should not be relied upon to heal or repair tendons. They will usually mask or make more subtle any injury and when you come off, it will be worse because you will be pushing your body harder while on gear and when off the damage will be noticeabley greater.

    From what I have researched steroids do not do much for tendon healing. But growth hormone will help much more so than any steroid would.
     
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  3. ambulldog

    ambulldog Member

    From all the research i did. A little test wont hurt. Like trt dose. Nithing else will help from an aas pov. Dont believe everything you read about deca. It will cushion the joints not help heal them.

    Just take the necessary time off and let it heal properly
     
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  4. ^^^ That!
     
    youngBuilder likes this.
  5. tenpoundsleft

    tenpoundsleft Member

    Start with PRP injections
    Add HGH, low dose, 3 months +
    Last resort, go with stemcell injections
     
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  6. CdnGuy

    CdnGuy Member

    Like each guy mentioned test,deca,GH
     
  7. ambulldog

    ambulldog Member

    Even with all of this its highly unlikely youll do anything but spend $$$.

    Surgical trauma
     
    youngBuilder likes this.
  8. tenpoundsleft

    tenpoundsleft Member

    PRP and HGH have done wonders for my tendonitis/tendinosis. Haven't had to go for stem cells yet.
     
    ambulldog likes this.
  9. ambulldog

    ambulldog Member

    Prp is very hit and miss for people. You are one of the fortunate ones.

    Hgh. Well there isnt a lot of backing on it healing tendons. Plenty of bro-science backing it but not legit medical studies.

    In the end. Post surgical recovery takes a lot of time. That time varies person to perso as you know.
     
  10. Phys Ther Sport. 2016 Jan;17:87-94.
    The clinical impact of platelet-rich plasma on tendinopathy compared to placebo or dry needling injections: A meta-analysis.
    Tsikopoulos K1, Tsikopoulos I2, Simeonidis E2, Papathanasiou E3, Haidich AB4, Anastasopoulos N3, Natsis K3.

    Abstract
    OBJECTIVE:
    The purpose of this meta-analysis was to compare the impact of platelet-rich plasma with that of placebo or dry needling injections on tendinopathy.

    METHODS:
    The databases of PubMed, CENTRAL, Scopus, Web of Science, and trial registries, reference lists, and conference abstract books were searched up to December 2014. Adults with tendinopathy in randomized controlled trials were enrolled. The trials compared effect of platelet-rich plasma with that of placebo or dry needling. We used subgroup analysis linked to the anatomical location of the tendinopathy. The primary outcome was pain intensity at two or three and six months after intervention. The secondary outcome was functional disability at three months after treatment.

    RESULTS:
    Five trials were included. There was a statistically significant difference in favor of the platelet-rich plasma intervention at the second primary outcome time point (SMD -0.48, 95%CIs -0.86 to -0.10, I(2) = 0%, p = 0.01) and at the secondary outcome time point (SMD -0.47, 95%CIs -0.85 to -0.09, I(2) = 0%, p=0.01).

    CONCLUSIONS:
    Platelet-rich plasma did not provide significantly greater clinical benefit versus placebo or dry needling for the treatment of tendinopathy at a six-month follow-up. However, there was a marginal clinical difference in favor of platelet-rich plasma injections on rotator cuff tendinopathy.


    Am J Sports Med. 2016 Jun 6.
    The Effectiveness of Platelet-Rich Plasma in the Treatment of Tendinopathy: A Meta-analysis of Randomized Controlled Clinical Trials.
    Fitzpatrick J1, Bulsara M2, Zheng MH3.

    Abstract
    BACKGROUND:
    Tendinopathy is very common in the general population. There are increasing numbers of clinical studies referring to platelet-rich plasma (PRP) and platelet-poor plasma (PPP) as treatments for tendinopathy.

    PURPOSE:
    To perform a meta-analysis of the outcomes of the PRP groups by preparation method and injection technique in tendinopathy. To determine the clinical effectiveness of the preparations and to evaluate the effect of controls used in the studies reviewed.

    STUDY DESIGN:
    Systematic review and meta-analysis.

    METHODS:
    The PubMed, EMBASE, CINAHL, and Medline databases were searched in March 2012, April 2014, and August 2015, and randomized controlled trials using autologous blood, PRP, PPP, or autologous conditioned plasma in tendinopathy with outcome measures of pain and follow-up time of 3 months were included in this review. Trials including surgery, tendon tears, and muscle or ligament injuries were excluded. Study quality was assessed using the Cochrane Collaboration risk-of-bias tool by 2 reviewers. Data were pooled using random-effects meta-analysis. The primary outcome measure was a change in pain intensity. Where more than 1 pain scale was included, a functional score was selected ahead of a visual analog scale score.

    RESULTS:
    A total of 18 studies (1066 participants) were included. Eight studies were deemed to be at low risk of bias. The most significant outcomes in the PRP groups were seen in those treated with highly cellular leukocyte-rich PRP (LR-PRP) preparations: GPS kit (standardized mean difference [SMD], 35.75; 95% CI, 28.40-43.10), MyCells kit (SMD, 31.84; 95% CI, 17.56-46.13), Prosys kit (SMD, 42.99; 95% CI, 37.73-48.25), and unspecified LR-PRP (SMD, 34.62; 95% CI, 31.69-37.55). When the LR-PRP system types were grouped, there was a strongly positive effect (SMD, 36.38; 95% CI, 34.00-38.77) when compared with leukocyte-poor PRP (SMD, 26.77; 95% CI, 18.31-35.22). In assessing the control groups, there was no clear difference between different types of control injections: saline (SMD, 14.62; 95% CI, 10.74-18.50), local anesthetic (SMD, 15.00; 95% CI, 7.66-22.34), corticosteroid (SMD, 23.82; 95% CI, 10.74-18.50), or dry needling (SMD, 25.22; 95% CI, 21.27-29.16).

    CONCLUSION:
    There is good evidence to support the use of a single injection of LR-PRP under ultrasound guidance in tendinopathy. Both the preparation and intratendinous injection technique of PRP appear to be of great clinical significance.


    Phys Sportsmed. 2015 Jul;43(3):253-61.
    Efficacy of platelet-rich plasma injections in pain associated with chronic tendinopathy: A systematic review.
    Balasubramaniam U1, Dissanayake R, Annabell L.

    Abstract
    BACKGROUND:
    Chronic tendinopathy has often been a management dilemma for general practitioners. With our understanding of the pathophysiology of tendinopathy evolving, so has our management, with the advent of newer strategies such as topical glycerol trinitrate, extracorporeal shock-wave therapy, as well as platelet-rich plasma (PRP).

    AIM:
    To systematically review the literature regarding PRP therapy in chronic tendinopathy.

    DESIGN AND SETTING:
    The databases used in our search include the Elton B. Stephens Co. (EBSCO) database, Medline, the Cochrane library, Ovid, and Embase (the Excerpta Medica database). A total of 389 articles were reviewed from Feb 2010 to April 2014, for possible inclusion. Of these articles, a total of 9 randomized controlled trials (RCTs) met our inclusion criteria. Only 1 RCT was excluded due to previous surgery in both the trial and control groups.

    METHODS:
    Each article was reviewed independently by 2 authors. Each article was analyzed using the Cochrane Criteria checklist. Where any discrepancy occurred in results, a third independent reviewer was consulted.

    RESULTS:
    Our review found that PRP was most effective in patellar and lateral epicondylar tendinopathy, with both RCTs in the patellar section of our study supporting the use of PRP in pain reduction at 3 and 12 months, whereas 2 of 4 studies in the lateral epicondylar section showed improvements in pain and disability at 6 and 12 months. There was a lack of evidence to support the use of PRP in Achilles and rotator cuff tendinopathy.

    CONCLUSIONS:
    Although the results of this review show promise for the use of PRP in chronic tendinopathy, the analysis highlighted the need for more controlled clinical trials comparing PRP with placebo.
     
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  11. tenpoundsleft

    tenpoundsleft Member

    @CensoredBoardsSuck

    Good content.

    It's worked for me.

    I can add that intratendinous injections feel really unpleasant.
     
  12. drippie

    drippie Member

    +1 for hgh and for the win
     
  13. legendary

    legendary Member

    I'm a believer of tb500
     
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  14. Milk Man

    Milk Man Member

    Pull the tendon out and replace with bungee cord.
     
  15. youngBuilder

    youngBuilder Member

    Lots of HGH mentions...

    Funny because I "jokingly" asked the surgeon if GH would help speed up recovery and to hand over a script. He said, in a serious tone, that recent studies don't support any accelerated-healing of tendons with GH. And coming from a surgeon from the top hospital in NE... I still want to disagree with him (lol).
     
    ambulldog likes this.
  16. ambulldog

    ambulldog Member

    Ive seen studies that state exactly that. But bro science and placebo win time after time lol
     
    youngBuilder likes this.
  17. youngBuilder

    youngBuilder Member

    +1 for broscience.
     
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  18. ambulldog

    ambulldog Member

    And placebo. I knew a guy with 2 herniated discs lower back. He was doing pt, chiro etc. Decided to go on gh. 2 weeks later his back was better.

    What he tell everyone? Fuck the pt and chiro gh is the way to go healed me in 2 weeks lol
     
  19. Dr JIM

    Dr JIM Member

    To date what little interventional orthopedic research has been conducted on AAS has NOT been FAVORABLE

    Thus from an evidence based perspective, AAS are NOT believed to be helpful and MAY in fact be harmful during the post-operative period, and is one reason AAS are not FDA approved for this indication.
     
    Michael Scally MD and ambulldog like this.
  20. Dr JIM

    Dr JIM Member

    Then you might want to become more familiar with the EVIDENCE as is this surgeon.

    That is of course, unless you aimlessly choose to believe an anecdote of one, or the collective few, is of greater statistical significance than the multitudes of studies that have investigated this very issue.
     
    ambulldog likes this.