This channel is interesting: Weight Lifting Dermatologist This guy gathered a few endos to discuss TRT topics, among which Dr Keith Nichols. They are big proponents of scrotum transdermal applications for stable T levels and rocket high DHT levels. Their main position is that: given the amount of xenoestrogens in litteraly everything today, most men's androgen receptors are saturated and can't receive androgens properly. So even if you have T levels in the 800s today, you are most likely only receiving the equivalent androgenic activity of someone who was in the 200s back in the 1950s. Their conclusion: don't go by number, but by feel. If it takes 300mg of test per week to feel good and TT levels in the 2000s, then that's what it takes and should be on this year round. @Michael Scally MD @Dr JIM does that theory hold any water?