Free vs. Total testosterone.

Discussion in 'Men's Health Forum' started by chemman, Jan 11, 2010.

  1. tenpoundsleft

    tenpoundsleft Member

    Well, it's primarily a TRT regimen for me, so not trying to attain several thousands of TT. And mainly trying to get better educated.
     
  2. MR10X

    MR10X Member

    earlier test
     

    Attached Files:

  3. MR10X

    MR10X Member

    while on 120 mg test e a week,no other drugs
     

    Attached Files:

  4. LW64

    LW64 Member

    'Primarily a TRT regimen' and a 'little bit' AAS?

    That's like being a 'little bit' pregnant.
     
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  5. tenpoundsleft

    tenpoundsleft Member

    Come on, TRT relies on AAS, but as you can see from my test results, it's in "normal" range. I'm just trying to stay on the "optimal" side of normal. Otherwise I would call it a cycle - and yes, technically TRT is a lifelong cruise kind of "cycle" but that's pushing the semantics to a point where it becomes a useless word.
     
  6. LW64

    LW64 Member

    From a TRT perspective, there is nothing normal about what you're doing so there can be no 'optimal side' to it.
     
  7. virginian

    virginian Member

    Look carefully at the units. My lab (Quest) reports TT in units of ng/dL and reports free T in units of pg/mL. To convert the free T to the same units as TT, divide by 10. If your lab does the same as Quest, your free T in units of ng/dL is 27.7 and your percent is 1.8. Those look like good numbers to me.
     
  8. Michael Scally MD

    Michael Scally MD Doctor of Medicine

    Actually, you are doing more than that! pg to ng = 1000; ml to dl = 100. Thus, taking both into consideration provides your shortcut.
     
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  9. Michael Scally MD

    Michael Scally MD Doctor of Medicine

    Pastuszak AW, Gomez LP, Scovell JM, Khera M, Lamb DJ, Lipshultz LI. Comparison of the Effects of testosterone Gels, Injections, and Pellets on Serum Hormones, Erythrocytosis, Lipids, and Prostate-Specific Antigen. Sex Med 2015;3(3):165-73. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599554/

    INTRODUCTION: Numerous testosterone (T) formulations are available, each with differing effects on serum parameters. AIM: The aim of this study was to compare the long-term effects of topical, injectable, and implantable pellet T formulations in hypogonadal men.

    METHODS: Retrospective review of hypogonadal men treated with a single T formulation was performed: 47 men on T gels, 57 on injectable T, and 74 on T pellets were identified. Total T (TT), calculated free T (FT), estradiol (E), hemoglobin (Hgb), hematocrit (Hct), prostate-specific antigen (PSA), total cholesterol (Tchol), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol were evaluated at baseline and every 3-6 months for 3 years. Serum parameters were compared using a mixed model linear regression for repeated measures.

    MAIN OUTCOME MEASURES: Effects of topical, injectable, and pellet T formulations on serum hormone levels, Hgb, Hct, lipid parameters and PSA.

    RESULTS: Men in the injectable T group were younger (42.5 +/- 12.3 years) than in the gel (54.1 +/- 9.8 years) or pellet groups (53.8 +/- 13.0 years), and baseline FT, Hgb, and Hct were higher in the injectable T group than in gel or pellet groups. Increases in TT and FT were observed throughout follow-up in all groups. Increases in E were observed at in all T groups and throughout follow-up in injectable and gel groups. No PSA increases were observed. Erythrocytosis (Hct > 50%) was more common with injectable T (66.7%) than with T gels (12.8%) or pellets (35.1%, P < 0.0001). Transient changes in cholesterol, TG, and LDL were observed, and no significant changes were seen in HDL for any group.

    CONCLUSIONS: All T formulations increase serum T and FT. More significant increases in E occur with injectable T and T gels. Changes in Hgb and Hct are most significant with injectable T, and effects on lipids are variable and inconsistent. Selection of T formulations must account for individual patient preferences and the effects of each formulation.
     
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  10. Dr JIM

    Dr JIM Member

    ^^^^^
    Good stuff Doc :)
     
  11. Dr JIM

    Dr JIM Member

    Let's see your TT is 713ng/dl. So unless you misplaced a decimal point or copied the wrong TRT is NOT indicated. Call it what it is, CYCLING or CRUISING either are fine but TRT, NOT!
     
  12. MR10X

    MR10X Member

    Thats what my endo said also even with low FT and low T symptoms