Good day, Throughout the forum members discussing HGH often it seems to be more heresy than actual scientific texts. I have found two documents that seem to offer excellent information into HGH and the Freeze-drying process. Vacuum-Induced Surface Freezing for the Freeze-Drying of the Human Growth Hormone: How Does Nucleation Control Affect Protein Stability? - ScienceDirect Europe PMC A couple of very dry reads but informative and could help someone make some educated decisions. The docs include discussions of what should be in your HGH (Mannitol) and how and why they came to these conclusions.