That's the first I've heard of HCG affecting thyroid hormone/activity. I'd be interested in some more information on this topic. It's always amazed me how the vast majority of doctors ignor these other bodily actvities when they dismiss HCG as a TRT option. Please recheck your research on this. I researched this issue a while back concluded that this is a misconception. Here's why. When a doctor suspects testicular cancer (TC) he does a blood test for HCG. Elevated HCG is an indication that TC is present. However, there is no research that indicates HCG causes TC. But it is understandable that some people might mistakenly think that it does because of the first sentence in this paragraph. Unlikely as long as your careful and knowledgable. Unlikely with subq injections. With HCG at $45 a vial for 2 months, can you get much cheaper than that? With my insurance, I pay $20 for 3 vials which lasts me six months. At $3.33 a month, I doubt anyone is paying less than that for standard TRT. Been on at least 30 flights with needles in my carry-on. They've never once stopped to take a look at them. Although they stop me every time to look at my small round-tipped scissors (although I understand that's about to end ). I both inject (HCG) and apply cream (DHT) daily. I actually find the cream about as inconvenient as injecting. The inconvenience with cream is that it limits your activity for about 2 hours or more after you apply it. This stuff is over my head, so I won't comment on it.