I was reading a thread at the World Class Bodybuilding Forum about Kryptocur (see Kryptocur - World Class Bodybuilding Forum) and it got me thinking that it could be used to prevent HPG suppression instead of just for pct. During a cycle, the hypothalamus detects circulating T and E2 and secretes less (if any) GnRH. Subsequently, the pituitary is not stimulated to release gonadotropins (i.e. pituitary shutdown). And without gonadotropins, the testes shut down (no T, no spermatogenesis). In theory, one could keep the entire HPTA stimulated by using GnRH while on steroids. The idea would not be to get the testes to produce T in significant levels, but rather to prevent the HPTA from shutting down. GnRH injections aren't practical because of the very short half life. However, GnRH nasal spray (Kryptocur) addresses the problem of short half life: as directed, it is supposed to be used 3 times a day, one spray in each nostril. Each spray contains .2 mg of GnRH. That's 1.2 mg of GnRH per day. I have no idea how appropriate this dosage is for purposes other than inducing testicular descent in boys with cryptorchidism, which is what Kryptocur is actually indicated for. Kryptocur is legitimate; you can find plenty of studies on it validating its effectiveness (kryptocur - Google Scholar), although it is not available in the US (its used in Europe). The only form of HPG shutdown that would be possible while using GnRH would be hypothalamic shutdown. While I've heard of primary hypogonadism and secondary hypogonadism (hypogonadotropic hypogonadism) resulting after the cessation of steroid use, I've never heard of tertiary hypogonadism (hypothalamic hypogonadism) resulting from it. Any thoughts? Has anyone ever tried using Kryptocur on a cycle to prevent shutdown?