SARMs or selective androgen receptor modulators are like steroids 2.0. It makes sense when you think about it. My personal favorites are Ligandrol Ibutamoren Testolone and YK11 . These are all new drugs designed to treat all the conditions that anabolics were created for in the first place. Cardarine dramatically improves physical performance. It's a antagonist of the PPAR d receptor. Peroxisome proliferator-activated receptor delta. Made me feel almost manic. These are not to be trifled with. But when deca durabolin was invented it wasn't to be a great anabolic for otherwise healthy men to take. Nandrolone esters are used in the treatment of
nemias,
cachexia (wasting syndrome),
osteoporosis,
breast cancer, and for other indications. If you look at the patent applications for these drugs you will see that they are all looking to treat the same disorders or diseases.
Trust me brothers. This stuff is serious. I almost didn't want to make a big thing out of it because its better left the way it is. Where they can be used like research supplements. But we all know that's bullshit. The only research we're doing is how to get huge and lean. Maybe we should publish this because it sure can make your life better.
They really aren't though.
First off, Cardarine isn't a SARM and I am personally in the camp that it is very deleterious to human health.
Read this, it's only a paragraph. I wouldn't touch cardarine with a 10 foot pole. The
doses people use are far too close to the doses given in animal studies that were found to be carcinogenic to literally a dozen different tissues and organs (as seen in the paragraph linked above). So yeah, cardarine fucking sucks.
Also, speaking of cardarine, who
really needs to buff up their cardio capabilities that much? Is it really that hard to run 30 minutes on the elliptical or bike for an hour or 90 mins? Come on peeps, you can do better than that. The only thing I could see it potentially beneficial for is extremely short term use to help you hold your breath during snorkeling or free-diving spearfishing. That's literally the only use case I can think of lol. Even for that though, you could just try
ITPP.
YK11 also is really closer to a normal AAS than a SARM. Unfortunately it is only a partial agonist of androgen receptors. Essentially it has other actions but the primary mechanism really is to increase follistatin levels--thus decreasing myostatin and allowing the body to build muscle better. IMO YK11 is a very interesting drug, as all myostatin inhibitors are. However, there is essentially zero safety and we really don't have a good enough understanding of the consequences of myostatin inhibition to really say it is safe. I am definitely not comfortable taking it (I say that as I pin 250 mg of Test C and 50 mg of NPP into my leg while popping 20 mg of Anavar and .5 mg of anastrazole).
The main issue I have with SARMs is that people take WAY TOO FUCKING MUCH. You don't fucking need 20 mg of RAD140 or 40 mg of Ostarine or 15-20mg of LGD. These gym bros are fucking themselves up for no goddamn reason. You will get almost equal effects from 5 mg as from 10 or 15, just with far less side effects. This is because the dose response curve for SARMs appears to be logarithmic, essentially is goes up quickly at first (e.g., from 0.5 to 1 mg) then tapers off (e.g., from 1 to 2.5, 2.5 to 5, and especially over 5 mg for LGD/RAD)
SARMs can cause gyno too, you know. They increase free test drastically and thus that gets converted to E2 and can cause gyno.
Overall, traditional AAS have WAY more safety data behind them, so people can actually know what the hell they are getting into. It just doesn't make sense to take an untested research chemical that is going to fuck up your lipids and endocrine system and liver enzymes when you could just blast 500 mg of Testosterone and get MUCH better effects, less side effects, and really no notable effect to liver enzymes and often a smaller effect to lipid profile than SARMs cause as well.
Test is best. It rhymes, but it is also
true.