Dear Bill,
A question related to your article on the drug development of anabolic steroids: Given the low virilization property of Oxandrolone and Methenolone, would this suggest that they have less psychological side effects (aggression, irritability, etc. – what is informally known as “roid rage”)?
Yuval
Answer:
Much activity in the brain attributed to testosterone is in fact caused by estrogen. The brain has high levels of aromatase. Some activity, however, is directly androgenic: for example, DHT is neuroactive, but cannot aromatize to estrogen.
Your thinking is logical, and it is indeed noted that the AAS you mention are not known for increasing aggressiveness. Perhaps that is the reason. I am not aware of where that has been proven.
Dear Bill,
I am 23 and have been lifting for around 8 years off and on. My problem is my lack of growth.
My question is, is HCG a very common drug? I am looking for about 20 lbs worth of mass, while cutting my body fat. Clomid sounds like the best way to help your body snap back. And HCG is not detectable by drug tests. I am not sure if this dealer has clomid, so is there a way I could get it from a doctor? One thing is clear, I do not want to do multiple cycles, and I want to keep what I get.
HCG is commonly available in Mexican pharmacies, and commonly available by prescription in the United States for men with infertility problems, as is Clomid.
You do not mention AAS use anywhere here. HCG and Clomid by themselves would be of little use, and certainly a “cycle” using them would produce no long-lasting retained gains.
For that matter, it is impossible to keep indefinitely all that one gains on a steroid cycle. Once the hormonal environment is back to normal, the physique will begin to revert to normal. There is some lifetime retention of gains in my opinion, but the greater fraction of the gains will be lost.
Dear Bill,
I am looking for an AS that will not blow my system out ( harm it), one that will help me get cut from it, gain about 20 max of mass, increase my performance in a long term aspect, and be easy to recover from. But the two main things are: low toxicity and short period of time in the body.
These are conflicting goals. Gaining muscle and cutting do not go well with each other, and doing only one cycle and expecting major long term results is not realistic.
I do not want my liver “shooting craps” on me. I want to do this the safe way, with a little cheating, ya know. I would like your help and advice on what to look for.
It sounds as though you want to be conservative. Conservative choices of drugs include Primobolan, Deca Durabolin, and testosterone if combined with anti-estrogen drugs.
If I get a full cycle, would it be good to split it in half so that my growth does not get out of control?
It is unlikely that your growth will get out of control.
8 weeks would be reasonable.
Dear Bill,
I’m an 18 year old that weighs a measly 140. I really want to increase my muscle mass and weight. I have a weight set…..but I’m unsure about what kinds of foods that are good to eat while training, and I want to develop some sort of basic plan which will suit my needs.
Sam
This will depend somewhat on your physique type.
If you are the naturally rail-thin type, who doesn’t put on much bodyfat no matter what he eats, then you need not be so careful. You could continue to do things like eat ice cream. Whereas if you are the bodytype which puts fat on easily, then you should make sure almost every meal is good nutrition.
That means from about 20-40 or more grams of protein per meal, fat calories probably not much above 1/3 of the total calories, avoiding partially-hydrogenated fats, and avoiding sugar including high fructose corn syrup.
You should eat every two or three hours.
If this does not seem practical, the meal replacement products such as Met-Rx can help.
The main thing is, don’t put your body into periods of starvation, as is the case when one goes many hours between meals.
There is almost nothing that all bodybuilders agree on, but this is something everyone agrees on: You need to eat at least five or six meals a day. That does not necessarily mean more total food: the meals will probably all be smaller.
Dear Bill,
I recently went to Mexico and purchased a few boxes of Primobolan 5mg tabs and Deca 50mg redijects! I took 1cc of deca so far and about 15mg of Primo (3-4 tabs) a day! How much Primo should I take a day!
I cannot say what you “should” do, but I can tell you that for a male (you did not say if you were male or female though) that dose will do nothing for gains. It really is not a practical drug for that purpose.
I wanted to make sure the primo was real and see if that could be causing my severe head pains!
Real Primobolan would be very unlikely to cause head pains.
Hi Bill,
In a month or so I will be going on a cycle of D-bol (25mg/day) and Deca (400mg/week). I want to use an antiaromatase, because I have earlier had problems with d-bol (gyno began to show up). I have cytadren, but I’m not 100% sure how it works in the body and what side effect I may encounter while using it. And finally, how is it safely used (dosage, tapering, etc.)?
BTW, would nolvadex be useful in any way stacked with d-bol/deca/cytadren?
Regards Fred
Cytadren works by inhibiting the aromatase enzyme: binding to the same site that the AAS molecule needs to bind to, and thus blocking it.
Unfortunately it also inhibits the desmolase enzyme which ultimately is necessary for cortisol production.
At 250 mg/day, the inhibition of desmolase is relatively much less than that of aromatase. So one can get reasonable (though incomplete) aromatase inhibition with moderate desmolase inhibition. Nonetheless, the body will compensate for the inhibition in cortisol production, by increasing ACTH. (Higher ACTH results in higher cortisol.)
The body, in effect, learns to produce the same amount of cortisol as before, even though the desmolase enzyme is somewhat inhibited.
What happens then when you discontinue Cytadren, and the desmolase inhibition is ended?
High cortisol levels.
Cytadren has a longer half life than Dianabol. Thus, if Cytadren is taken at the same time as the Dianabol, it will last long enough to provide aromatase inhibition while the Dianabol is in the body.
So if you took the Dianabol only once in the morning, for example, then only one dose of Cytadren would be needed, at the same time. Half a tab would suffice, unless a lot of Dianabol is used (over 40 mg let’s say) in which case perhaps ¾ tab would be better.
If you take it more frequently, then a half tab in the morning, and quarter tabs up to twice later in the day, would be conservative and reasonably effective.
Stacking with Clomid would be wise. Nolvadex would be comparable in effect.
Dear Bill,
This may sound ridiculous to you, but can I come up positive for Deca on a steroid test?
Yes, if you have used it, or if you have recently used norandrostenedione.
But perhaps you are asking, will Deca be detected on an ordinary drug test given to ordinary employees, not to athletes? No. It must be looked for specifically, and they do not do this for the general population.
Also, what is the maximum time that you have heard that real Deca stays in your system?
Brian & Carrie
It is common to detect it even after six months. I can’t recall the maximum I have ever heard of but I think it was 8 or 9 months. Of course, Craig Titus claimed much longer than that, and perhaps some others have as well. Whether those claims are true or not is another matter.
Mr. Roberts,
I recently read your antiestrogen article, and have a couple of questions. I’m prone to gyno, and after a Sustanon/Dianabol cycle I do have a small lump to the side of each nipple. Here’s a copy of my current cycle, with which I’m taking clomid 25mg/day. What do you think of adding proviron, and what dosage would you recommend?
wk1 test prop 200mg, deca 200mg
wk2 300, 400
wk3 300, 400
wk4 300, 400
wk5 300, 400
wk6 200, 200
then switch to
wk7 para 76mg, anavar 15mg/d
wk8 152, 20
wk9 152, 25
wk10 228, 25
wk11 152, 20
wk12 76, 15
wk13 clomid 100mg/d
wk14 50mg/d
wk15 50mg/d
Starting lighter the first week makes little sense. Doing the same, or doing double, makes more sense.
The same applies to ramping up the Parabolan; that is, assuming you can get the real thing.
It looks as though you are trying to taper the Parabolan. That is not necessary. You could take nothing on week 11, relying on what is already in the system, then if desired, Primo on week 12.
I personally would make the cycle shorter.
In any case, to your question: The Proviron would be of some value during the weeks with testosterone, and until the testosterone is out of the system. If you are using a long lasting ester, that might be three additional weeks or so.
Clomid is probably more cost effective.
I would not use 100 mg/day Clomid at the end, but instead use 50. You would have no aromatizable drugs in the system anyway. There is no need to try to drive estrogen receptor activity down to zero. In fact that would be undesirable, since some estrogen is needed for LH production.
The Clomid might as well be 50 mg/day all through the cycle.
Dear Mr. Roberts,
How would you feel about a stack containing the supplements of norandro, andro, tribulus, and diol-5. How would you take them and what would you change about the stack.
Andy
If it were me, I would consider only androdiol and norandrodiol. 5-androdiol would be out of the question. I don’t know whether tribulus works or not. It won’t hurt, so if you want to try the gamble, why not?
If the andro products are taken around the clock, I expect that this would lead to inhibition of natural testosterone production. Thus, I would not use them after 4 PM, or 6 PM at the latest. That way, they are essentially out of the system while you sleep, and for a good part of each 24 hour period.
Dear Bill,
I purchased a bottle of OSMO 50tm 60 Capsules from GNC. When I took it home and read the bottle it said no one over 50 should use it.
Well, they have no study to show that it is unsafe. They are probably being conservative because many men over 50 have prostate problems, which this product could aggravate. Older men are also more likely to have prostate cancer, which would definitely be aggravated by this product.
When I went back to GNC to purchase more they told me that they had been pulled because many of the companies that were manufacturing Androstene were not testing them and were found to not have the ingredients that they claimed on the bottle.
My understanding is that GNC is leery about carrying the andro products, even though they are legal.
My question is, should a man my age be taking Androstene (even if I did not experience any side effects.)
A prostate examination would be a good idea. You have to decide whether the small risk of the andro products is worth the benefit to you.
Androdiol would have less risk in this area, and besides this, will be more effective. Norandrodiol would have even less risk.
Is it true about the companies not testing the ingredients and there are false claims about this stuff?
It is true that some company’s are disreputable and sell products which do not contain what the label claims. OSMO, however, is a reputable company.
What can I expect from Androstene at my age?
It (or one of the diols) may improve your workouts, improve muscle mass a little, and perhaps help with keeping fat off. It may improve sexual desire.
Where is a reliable place to purchase it that will guarantee me that I am getting what I paid for
Tony.
Well, at the risk of sounding like a plug, Meso-Rx. Substrate Solutions or OSMO would be good brand choices.
Dear Mr. Roberts,
My name is Chris, I am currently in the USMC. I am taking Symbiotrophin pro hgh and stacking it with Creatine. I’ve been using this combination for three weeks and I’ve notice some strength increases and my friends say that they can see the weight gains. Do you suggest to continue with this program as suggested on the container (for six months). Or finish this month and try something else.
The creatine is well proven. Obviously the cost depends on the amount bought, etc., but 5 grams per day maintenance just doesn’t cost much. So I would stay on it.
The other product you mention is an unknown.
With unknowns, I prefer to periodically take time off of the product, and see if I do just as well without it. If that is the case, especially if that happens more than once, then I drop using that product.
About the author
Bill Roberts is an internationally-recognized expert on anabolic steroids and performance-enhancing drugs (PEDs). He received a bachelor degree in Microbiology and Cell Science and completed the educational and research requirements for a PhD in Medicinal Chemistry at a major American university.
Bill entered the nutritional supplement industry prior to completing his doctoral thesis but his education was invaluable so far as being able to design/improve nutritional supplement compounds, since it was in the field of designing drug molecules and secondarily some work in transdermal delivery.
His education was not specifically "geared" toward anabolic steroids other than expertise with pharmacological principles having broad applications. This has allowed Bill to provide unique insight into the field of anabolic pharmacology with knowledge of points which he would not have known otherwise.
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