• Skip to main content
  • Skip to secondary menu
  • Skip to primary sidebar
  • Skip to footer
  • Steroid Profiles
  • Steroid Articles
    • Contributors
  • Steroid Forum
MESO-Rx

MESO-Rx

Anabolic Steroids

  • Anabolic Steroids
    • Anadrol
    • Anavar
    • Deca Durabolin
    • Dianabol
    • Equipoise
    • Masteron
    • Oral Turinabol
    • Primobolan Depot
    • Sustanon 250
    • Testosterone
    • Trenbolone Acetate
    • Winstrol Depot
  • hGH & Peptides
    • CJC-1295
    • GHRP-6
    • hGH
    • hCG
    • IGF-1
    • Melanotan II
    • MGF
    • Mod GRF 1-29
    • TB-500
  • Anti-Estrogens
    • Arimidex
    • Aromasin
    • Clomid
    • Letrozole
    • Nolvadex
  • Fat Loss
    • AICAR
    • Albuterol
    • Clenbuterol
    • DNP
    • Ephedrine
    • T3
    • Telmisartan
You are here: Home / Steroid Articles / How to Use Primobolan Depot

How to Use Primobolan Depot

September 10, 2001 by Bill Roberts

Schering Primobolan Depot - Methenolone Enanthate

Primobolan Depot (methonolone enanthate) is a Class I steroid working well at the androgen receptor but which apparently is ineffective in non-AR-mediated anabolic effects. It is most closely compared to Deca Durabolin, requiring a little higher dosage to achieve the same anabolic effect, but since it is pleasant to use at doses considerably higher than what is pleasant for nandrolone esters, it can achieve higher maximal effectiveness. That is, provided that one can afford it a gram per week of Primobolan Depot can be costly. 400 mg/week should be considered a reasonable minimum dose.

Primobolan Depot appears to cause less inhibition than Deca Durabolin or testosterone for any given degree of anabolic effect, perhaps because of low CNS activity, lack of conversion to DHT, and lack of aromatization to estrogen. Unlike Deca, it is not metabolically deactivated by 5a-reductase and therefore is not as kind to the skin and hair as that drug.  However, when used by itself at modest doses, by suppressing natural testosterone and DHT production, it can improve skin relative to using no anabolic steroids at all.

The half-life is probably about 5 days.

Methenolone enanthate is particularly excellent for use as the last injectable used in a cycle, since for any given anabolic effect it gives much less inhibition than other steroids such as testosterone, nandrolone, or trenbolone. Therefore, residual levels of Primobolan can allow recovery in the taper while still offering useful anti-catabolic or even anabolic support.

Bayer Schering Primobolan Depot - Methenolone Enanthate
Bayer Schering Primobolan Depot – Methenolone Enanthate

About the author

Bill Roberts
Medicinal chemist

Bill Roberts is an internationally-recognized expert on anabolic steroids and performance-enhancing drugs (PEDs). He received a bachelor degree in Microbiology and Cell Science and completed the educational and research requirements for a PhD in Medicinal Chemistry at a major American university.

Bill entered the nutritional supplement industry prior to completing his doctoral thesis but his education was invaluable so far as being able to design/improve nutritional supplement compounds, since it was in the field of designing drug molecules and secondarily some work in transdermal delivery.

His education was not specifically "geared" toward anabolic steroids other than expertise with pharmacological principles having broad applications. This has allowed Bill to provide unique insight into the field of anabolic pharmacology with knowledge of points which he would not have known otherwise.

Filed Under: Steroid Articles Tagged With: primobolan depot

No replies yet

Start the discussion →

Loading new replies...

Join the full discussion at the MESO-Rx →

Primary Sidebar

Sponsors

Popular Articles

2000 summer olympics sydney

Let’s Ban Those Who Don’t Use Steroids

At the conclusion of the twenty-seventh Olympiad still another set of athletes was found guilty of using steroids and other performance-enhancing drugs and were sent home in disgrace. Yet the facts concerning … [Read More...] about Let’s Ban Those Who Don’t Use Steroids

Managing steroid side effects

Anabolic Steroid Side Effect Management Table

Anabolic steroid (and testosterone) side effects management table courtesy of Nelson Vergel and Michael Mooney (excerpt from the book "Built to Survive") Problem Solution and Comments Acne/oily skinCaused … [Read More...] about Anabolic Steroid Side Effect Management Table

androgen receptors

Androgen Action and the Androgen Receptor

Introductory Physiology and Pharmacology of Androgens Endogenous androgens are well known for their many functions in promoting sexual differentiation and the induction of the male phenotype. In the male, the two … [Read More...] about Androgen Action and the Androgen Receptor

Stanzolol insights

Stanozolol Insights: Unique Characteristics of Anabolic-Androgenic Steroids – Part 2

Introduction This is part two of an eleven-part series (2 / 11) that will delve into the unique features of anabolic-androgenic steroids (AAS) by compound or drug. The first part (1 / 11) looked at trenbolone’s … [Read More...] about Stanozolol Insights: Unique Characteristics of Anabolic-Androgenic Steroids – Part 2

Selective Androgen Receptor Modulators (SARMs)

Selective Androgen Receptor Modulators for HIV Wasting and Cancer Cachexia

Will Selective Androgen Receptor Modulators Replace Anabolic Steroids? Oral selective androgen receptor modulators (SARMs) are investigational agents. Studied since 1998, they are still very much in the infancy of … [Read More...] about Selective Androgen Receptor Modulators for HIV Wasting and Cancer Cachexia

Footer

MESO-Rx International

MESO-Rx articles are also available in the following languages:

Deutsch, English, Español, Français, Português, Русский

Questions? Comments?

Use the following link to send us an e-mail. We will respond as soon as we can.

Contact us.

Search

Copyright © 1997–2025 MESO-Rx. All rights reserved. Disclaimer.