Our body is an enigmatic soup of many hormones and growth factors that determine how we develop, grow and age. One of the hormones primarily responsible for much of our early growth is aptly named ‘growth hormone.’ Like most growth factors in the body, growth hormone is a secreted protein that exerts multiple effects on […]
Anabolic Steroid Articles
Our steroid articles provided detailed, practical information on how anabolic steroids are used to build muscle size, strength and otherwise improve physical performance. They cover topics such as the history of steroids, steroids in baseball, the medical uses of steroids including testosterone replacement therapy (TRT), the side effects of steroids and how to manage steroid side effects.
Androgen Receptors Downregulate Don’t They? Part 2
In part 1 of this article we discussed the mistake of thinking about androgen receptors (testosterone receptors) in the same way we think of other receptors such as beta-receptors. Beta-receptors down regulate in response to beta-adrenergic stimulation whereas there is good evidence that androgen receptors increase in numbers in response to androgens. We also discussed […]
Androgen Receptors Downregulate Don’t They? Part 1
There is as much misinformation about steroids as there is good information had among bodybuilding enthusiasts. Go to any gym and you will hear some kid spouting off to his buddies about how steroids do this, or how they do that, or whatever. This soon starts somewhat of a pissing contest (excuse the expression) as […]
The Thyroid Gland Part 2 – How to Renew its Activity During a Diet
The thyroid gland and the hormones that it produces are among the key factors which determine the success or failure of a diet. Because thyroid hormones are regulators of basal metabolism, they determine the daily consumption of calories. A strict diet downregulates the activity of the gland. This lowers the daily requirement in calories, obliging […]
The Thyroid Gland Part 1 – Fat Loss, Muscle Growth, and Diet
In this series I am going to write about the thyroid gland and the hormones that it produces (or that it no longer produces). Although the term “thyroid”‘ is often associated with fat loss, the thyroid also helps to gain or lose muscle. It therefore has other functions which will be described after we have […]
Nandrolone Positive Steroid Tests – What Do They Mean?
Drug testing using IOC standards is far from perfect. For more than two decades I have criticized the short sightedness of the IOC drug testing standard bearers. And much of what I said in that period of time has turned out to be right. Among many others, I criticized, right from the start, the flawed […]
What Do We Tell Teenagers About Anabolic Steroids?
Rick Collins’ Advice to Teenagers (excerpted from Legal Muscle) The way I see it, most everything has risks and benefits. That’s especially true of medications, such as anabolic steroids. The choice of whether or not to take steroids involves weighing the risks against the benefits. The risk include numerous possible side effects, including the possibility […]
DNP, Fat Loss and Bodybuilding
DNP (2,4-Dinitrophenol), an industrial chemical with various applications, has gained steady popularity as a fat loss tool. Boasting an astounding 50% increase in metabolic rate, it is able to contribute to reported fat losses of 10-12 pounds in 8 days of use. Classified as an “uncoupler of oxidative phosphorylation” medically, it is quite dangerous as […]
How to Use Letrozole (Femara)
Femara (letrozole) is a type II (non-steroidal) third generation aromatase inhibitor. Clinically it is used to treat postmenopausal women with either estrogen receptor positive or estrogen receptor unknown breast cancer. In women, tumors that contain estrogen receptors are classified as estrogen receptor-positive (ER+) tumors. For Letrozole to be prescribed, a given tumor must have been […]
How to Use Arimidex
Arimidex (anastrozole) is the aromatase inhibitor of choice. The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso […]