2,4-dinitrophenol (DNP) was a weight-loss drug that hit the shelves in the USA in the 1930s. It was used as a dye and in French ammunition factories as an ingredient for bombs during the First World War. Workers and soldiers exposed to the compound experienced various side effects, including of course, weight loss. Later, in […]
Anabolic Steroid Articles
Our steroid articles provided detailed, practical information on how anabolic steroids are used to build muscle size, strength and otherwise improve physical performance. They cover topics such as the history of steroids, steroids in baseball, the medical uses of steroids including testosterone replacement therapy (TRT), the side effects of steroids and how to manage steroid side effects.
Anti-Doping: Producing Health or Harm?
Anti-doping can ignore the fact that strict policies against steroids may structure use environments in ways that result in greater potential risk. And these risks don’t stop with the physical. Rather, laws impact the entire use environment, including social, economic, and political risk factors.
Anabolic Steroids and Erythrocytosis Polycythemia
The use of anabolic steroids can lead to a condition called erythrocytosis. It’s a condition in which your body has too many erythrocytes, or red blood cells, in its blood.
Do Anabolic Steroids Make the Prostate Grow?
The dogma would ensure that anyone with prostate cancer, a history of prostate cancer, or at risk of prostate cancer, was denied any prospect of being treated for their testosterone deficiency with TRT. Gladly, the tide would turn in 2004.
The Rise and Fall of Cardarine (GW501516)
Introduction In 1990, researchers published the discovery of a new nuclear receptor—named the peroxisome proliferator-activated receptor ((PPAR)—in the journal Nature [1]. The name refers to the proliferation of peroxisomes, organelles of cells with a prominent metabolic function, upon activation of these receptors. This discovery would finally help solve the mystery of how a class of […]
Enclomiphene – A SERM That was Seeking FDA Approval for the Treatment of Hypogonadism
Repros Therapeutics Inc, made an attempt at making a SERM approved by the FDA for the treatment of secondary hypogonadism. Before I continue about how this process went, I’d like to provide some background on their SERM: enclomiphene citrate (brand name Androxal, later rebranded to EnCyzix).
Dude, make some space – Women’s experiences in an online steroid community
Historically, the use of steroids has more or less been a question of men, muscles, and masculinity. This “holy trinity” has long prevailed. By the 1970s, for example, we saw the bodybuilding icon Arnold Schwarzenegger and his bodybuilding buddies hitting the weights in the documentary Pumping Iron. At that time, and outside the sphere of […]
Anabolic Steroids and Fertility
Anabolic steroids don’t only affect the endogenous testosterone production, but also sperm production—a process called spermatogenesis. In this article I will walk you through how spermatogenesis works, how anabolic steroid use ties into this, and what you can possibly do about this.
Regulation of Testosterone Production
Introduction Most people are aware that testosterone, in men, is produced by the testes. A lot of people are also aware that this is the result of stimulation of the Leydig cell in the testes by a hormone called luteinizing hormone (LH). In turn, this hormone is produced in response to another hormone called gonadotropin-releasing […]
The Effects of Anabolic Steroids on the Heart’s Structure and Function
Perhaps one of the most worrying side effects of prolonged anabolic steroid use are those related to the heart. Indeed, a startling amount of case reports associating anabolic steroid use and adverse heart events have been published in the literature [1]. Most frequently, this included myocardial infarction. While case reports obviously can’t establish anabolic steroid […]