The thyroid hormone, thyroxine (T4) is a tyrosine-based hormone which is produced by the thyroid gland. Synthetic versions of this hormone are used to make up for a lack of naturally produced thyroxine and increase the rate of metabolism. Artificially made thyroid hormone improves the symptoms of hypothyroidism (underactive thyroid) and speeds the rate of […]
PEG-MGF (PEGylated Mechano Growth Factor)
What is PEG-MGF or PEGylated mechano growth factor? MGF is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for growth of adult muscle. Natural MGF is made locally and does not travel into the […]
MGF (Mechano Growth Factor)
MGF (mechano growth factor) has been used by bodybuilders and athletes for a few years already. After resistance exercise, IGF-1 is released within the muscle. Specifically, at this time, immediately following the mechanical use of a muscle, the IGF-I gene is spliced towards MGF which initiates hypertrophy and repair of local muscle damage. It does […]
Hexarelin
Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the growth factor family which stimulates the release of growth hormone (GH). It can be used medically to treat GH deficiency.
Fareston (Toremifene Citrate)
Fareston (toremifene citrate) is a Selective Estrogen Receptor Modulator (SERM) derived from triphenylethelyne. It is Licensed in the United States under the brand name “Fareston” and currently FDA approved for use in advanced (metastatic) breast cancer. It is currently being studies for use in prostate cancer as well. Background Toremifene Citrate was originally patented as […]
Evista (Raloxifene Hydrochloride)
Evista (raloxifene hydrochloride) is a second-generation Selective Estrogen Receptor Modulator (SERM). It is approved by the FDA for this use in women. Although it bears structural and mechanistic similarities to other SERMs which have been approved either as fertility drugs (Clomid) or Breast Cancer medication (Nolvadex), it has not been approved for either of those […]
How to Use Letrozole (Femara)
Femara (letrozole) is a type II (non-steroidal) third generation aromatase inhibitor. Clinically it is used to treat postmenopausal women with either estrogen receptor positive or estrogen receptor unknown breast cancer. In women, tumors that contain estrogen receptors are classified as estrogen receptor-positive (ER+) tumors. For Letrozole to be prescribed, a given tumor must have been […]
How to Use Aromasin
Aromasin (Exemestane) is one of those weird compounds that nobody really knows what to do with. What we generally hear about it makes it very uninteresting…It’s a third generation Aromatase Inhibitor (AI) just like Arimidex (Anastrozole) and Femera (Letrozole). Both of those two drugs are very efficient at stopping the conversion of androgens into estrogen, […]
Viagra (Sildenafil Citrate)
Viagra (Sildenafil citrate) is a drug used to treat erectile dysfunction (impotence) in males and pulmonary arterial hypertension (PAH). Background The pharmaceutical company, Pfizer, originally developed Viagra. In 1006, the FDA approved Viagra as the first drug patented for use of erectile dysfunction in the United States. They are blue, diamond-shaped pills with “Pfizer” marked […]
Levitra (Vardenafil)
Levitra (Vardenafil) is a PDE5 inhibitor which is used to treat erectile dysfunction. It can aid in achieving and maintaining an erection during sexual activity. Levitra is similar to Viagra (Sildenafil) and Cialis (Tadalafil) in effect; yet due to its shorter half live is closer in similarities to Viagra. Background Both Bayer Pharmaceuticals and GSK […]