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You are here: Home / Archives for Patrick Arnold

Articles by Patrick Arnold

Patrick Arnold, widely considered the "father of prohormones", is an organic chemist known for introducing androstenedione, 1-androstenediol, and methylhexanamine into the dietary supplement market. He became infamous for creating the designer steroid tetrahydrogestrinone, also known as THG and "the clear".

Arnold manufactured THG, norbolethone and desoxymethyltestosterone (DMT) for athletes in the BALCO doping scandal. The designer steroids, which were legal at the time of their creation, were difficult for anti-doping authorities to detect.

Ergopharm Response to Positive MLB Steroids Tests

January 13, 2009 by Patrick Arnold Leave a Comment

Ask Patrick Arnold - steroid chemist who created THG

Response to media inquiries about a MLB player who tested positive for a banned substance (reported to be androstenedione) and is attributing the result to his use of the dietary supplement product(s) 6-OXO or 6-OXO Extreme (January 13, 2009) The media has reported that baseball pitcher J.C. Romero has alleged that his positive test for the banned […]

6-OXO – The First Effective All-Natural Aromatase Inhibitor

November 9, 2008 by Patrick Arnold Leave a Comment

Ask Patrick Arnold - steroid chemist who created THG

For athletes familiar with prohormones and steroids, the female hormone estrogen is undoubtedly a familiar enemy. While most of us understand that estrogen is not necessarily always a harmful and worthless substance to men (in the right amounts it is necessary and beneficial), we still are aware that it must be kept under control or […]

DHT: Is It All Bad?

August 21, 2005 by Patrick Arnold Leave a Comment

A considerable chunk of my work day is always spent answering people’s questions about prohormones and steroids. Of course, one of the biggest concerns people have is about estrogen and estrogen related side effects. Right behind that however are questions about DHT. It seems that people have the misconception that DHT is some evil androgen […]

How to Make Anabolic Steroids Orally-Active?

December 29, 2002 by Patrick Arnold Leave a Comment

The subject of androgenic / anabolic steroids, and the different ways that have been found to make them orally active, has been tossed around lately on the internet mags. This is an interesting topic to the science minded out there, but beyond that, it also has potential utility to the prohormone supplements. The following is […]

Anabolic Steroids and the Drug Development Pipeline

December 29, 2002 by Patrick Arnold Leave a Comment

Ciba Pharmaceuticals and anabolic steroid development

I am told that articles on steroids are very popular. I guess there is some mystique surrounding chemicals that have the ability to dramatically transform one’s physique in a short period of time under the right conditions. You would think that people would get bored with this stuff after a while though, right? Well, apparently they don’t. […]

Lesser Known Pharmacological Ergogens

December 1, 2001 by Patrick Arnold Leave a Comment

Viagra (sildenafil) as a performance-enhancing drugs

The use and abuse of performance-enhancing substances by athletes has been an issue in sports since the ancient Greeks. Not until the advent of modern health science in the twentieth century though has performance enhancement presented such serious legal, ethical, and medical dilemmas. A person needs only to tune in to the television coverage of […]

Epogen / EPO (Erythropoietin)

epogen

EPO is an erythropoiesis-stimulating agent (ESA) that is sold in recombinant form (rhEPO) for injection. It usually is packaged as a lyophilized (freeze dried) powder that is reconstituted with sterile water before injection. One popular form is called Epogen (r), and it is made for subcutaneous usage. A starting dosage is typically 20 i.u. per […]

Androgens, Libido, and Sexual Function

December 1, 2000 by Patrick Arnold Leave a Comment

Anabolic steroids, libido and sexual function

Androgenic hormones such as testosterone and anabolic steroids (as well as prohormones) have long been used by athletes for their effects on increasing muscle mass and strength. The anabolic effect on muscle is certainly not the only physiological effect that these hormones possess however, and for many people not particularly interested in bigger muscles androgens […]

DHT (Dihydrotestosterone)

DHT

The main androgen secreted by the testes is of course testosterone. However, in most of the body, the androgenic signal is not carried through by testosterone. In these tissues, which include the brain (CNS), skin, genitals – practically everything but muscle – the active androgen is actually dihydrotestosterone (DHT). Testosterone in this case simply acts […]

Ask Patrick Arnold #15

November 22, 1999 by Patrick Arnold Leave a Comment

Ask Patrick Arnold - steroid chemist who created THG

Norephedrine and PPA; Dianabol and Drug Testing; Prohormone Enzyme Saturation; Saw Palmetto – Good or Bad?; Norandrodiol for Joint Pain; Effectiveness of Miscellaneous Supplements; Effective Anti-Estrogens

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