Trenbolone Enanthate is a strictly underground product, and not available for human use by any major pharmaceutical supply house in the world. It combines a very popular parent hormone (trenbolone) with a long acting ester (enanthate). This allows the advantage of once a week injections.
Background
For a fairly long time, the only version of legitimate Trenbolone available on the black market was Trenbolone Acetate. This was a fast acting version of Trenbolone often made from powder or cattle implant pellets. Since Parabolan (Trenbolone with a slightly longer ester) had been removed from the market, it developed a cult-like reputation, and a longer acting Trenbolone product was in demand on the black market. The underground labs of the time responded with Trenbolone Enanthate.
Steroid Action
Trenbolone Enanthate is a19-nor steroid, very similar to Nandrolone. The primary difference between Trenbolone is that there is a double carbon bond present at the 9 and 11 position on the steran nucleus. Trenbolone can not aromatize to estrogen nor be 5a-reduced.
It bonds very tightly to the Androgen Receptor, and for this reason it is thought that much of its fat-burning and muscle building abilities are receptor mediated.
Technical Data
Trenbolone Enanthate use produces an impressive amount of new muscle fiber, with minimal water retention (1) This may be done partly through an increase in IGF-1 within muscle tissue (2), and increased sensitivity of muscle satellite to IGF-1 and other growth factors(3) and an increase in the amount of DNA per muscle cell.
It has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4) as well as nandrolone.
Trenbolone increases both protein synthesis as well as nitrogen retention in muscle tissue (5). Trenbolone can also bind with the (anti-anabolic) glucocorticoid receptor (6-7), thus aiding the muscle building process.
Finally, it also has the ability to improve nutrient efficiency and mineral absorption in animals given the drug (8-9).
User Notes
You have probably noticed that there is no “Technical Data” for Trenbolone Enanthate per se (all of the studies cited are actually on Trenbolone with a different ester)
Well…there’s a very good reason for that. As noted previously, trenbolone enanthate is a strictly underground product…so while you will easily be able to find it available from GA Labs or DL Pharmaceuticals INC., you will not find it available from UpJohn or Steris. In fact, at this point, you will only find Trenbolone (Acetate) available in the veterinary industry.
In my experience with Trenbolone Enanthate, it is a very potent cutting agent, and will even help keep you lean while on a bulking cycle (it did for me, anyway). However, it will also cause some undesirable effects as well. It can cause insomnia and night sweats, as well as possible anxiety. It seems to not cause “tren cough” (coughing associated with Trenbolone Acetate) but still seems to reduce cardiovascular ability.
All in all, though, Trenbolone (any ester) is a really great drug for both building muscle as well as burning fat. It’s probably most people’s favorite behind testosterone, side effects be damned…and for good reason.
If you’re not a competitive athlete, this is a really great drug. Bodybuilders love the stuff, and we see it in many pre-contest cycles now-a-days. Athletes need to avoid it, however, because it simply reduces cardiovascular output too greatly, probably due to prostaglandin induced bronchial constriction.
References
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J Cell Physiol. 2004 Nov;201(2):181-9.
Endocrinology. 1989 May;124(5):2110-7.
Toxicol Sci. 2002 Dec;70(2):202-11.15
J Anim Sci. 1994 Feb;72(2):515-22.
APMIS. 2001 Jan;109(1):1-8.
J Anim Sci. 1990 Sep;68(9):2682-9.
APMIS. 2001 Jan;109(1):1-8.
J Anim Sci. 1992 Nov;70(11):3381-90.
About the author
Anthony Roberts is an expert in the field of performance and image enhancing drugs. He has authored books ranging from the pharmacology of anabolic steroids and growth hormone to their illicit use and trafficking. His writing can be found in magazines such as Muscle Evolution, Muscle & Fitness, Human Enhancement Drugs, Muscle Insider, and Muscular Development.