In part I of this series we discussed the effects of anabolic-androgenic steroid (AAS) use on the heart, the blood, cholesterol, and the liver. We also suggested some treatment options for the physician or health care provider. In this final installment we will discuss the side effects of the endocrine system including the testis, as well […]
Medical Supervision of Individuals Using Anabolic Steroids for Muscle Growth (Part 1)
Since the Anabolic Steroids Control Act of 1990 became law on November 29, 1990, physicians have struggled with the ethics of becoming involved with patients using anabolic steroids. There are serious repercussions for doctors’ accused of prescribing anabolic steroids to patients for physique augmentation. In addition, most doctors know very little about anabolic steroids and tend […]
Human Studies Finally Show Insulin to Be Extremely Anabolic in Human Muscle Tissue – In Vivo
Extreme hyperinsulinemia unmasks insulin’s effect to stimulate protein synthesis in human forearm. Researchers:Teresa A. Hillier, David A. Fryburg, Linda A. Jahn, and Eugene J. Barrett Division of Endocrinology and Metabolism, Department of Internal Medicine, and General Clinical Research Center, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908 Source:Am. J. Physiol. 274 (Endocrinol. Metab. 37): […]
Nubain Addiction in Bodybuilders
Nalbuphine hydrochloride dependence in anabolic steroid users. Researchers:Wines JD Jr, Gruber AJ, Pope HG Jr, Lukas SE. Alcohol and Drug Abuse Research Center, McLean Hospital-Harvard Medical School, Belmont, MA 02478, USA. Source:Am J Addict 1999 Spring;8(2):161-4 Summary: Nalbuphine hydrochloride, a nonscheduled opioid agonist/antagonist analgesic also known as Nubaine or Nubain, is currently approved for the […]
IGF-1 and Skeletal Muscle Hypertrophy
Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats. Researchers:Gregory R. Adams & Samuel A. McCue Department of Physiology and Biophysics, University of California, Irvine, Ca. Source:Journal of Applied Physiology84(5): 1716-1722, 1998 Summary:The present study was undertaken to test the hypothesis that direct IGF-I infusion would result in an increase in muscle DNA […]
IGF-1 Once Again Proves to be One of the Most Powerful Mediators of Muscle Growth
Not since the travels of Juan Ponce de Leon has the fountain of youth seemed so close! Title:Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function Researchers: Elisabeth R. Barton-Davis*, Daria I. Shoturma*, Antonio Musaro, Nadia Rosenthal, and H. Lee Sweeney*, * Department of Physiology, University of Pennsylvania […]
Scientists Hit Another Road Block in their Attempts to Detect Growth Hormone Use by Athletes
Growth hormone induced increase in serum IGFBP-3 level is reversed by anabolic steroids in substance abusing power athletes. Researchers: Karila T, Koistinen H, Seppala M, Koistinen R, Seppala T National Public Health Institute, Laboratory of Pharmacology and Toxicology, Helsinki, Finland. Source:Clin Endocrinol (Oxf) 1998 Oct;49(4):459-63 Summary: OBJECTIVE: Body builders may use growth hormone (GH) and […]
Is Blood Testing the Next Step in Doping Control?
The ethics of blood testing as an element of doping control in sport. Researchers/Authors:Alister Browne, Victor Lachance, and Andrew Pipe Division of Health Care Ethics, The University of British Columbia, Vancouver, British Columbia; and the Canadian Center for Ethics in Sport, Ottawa, Ontario; Division of Cardiac Surgery, University of Ottawa Heart Institute & Department of […]
Researchers Too Quick to Blame Steroids for Changes in Heart Muscle
Left ventricular wall thickening does occur in elite power athletes with or without anabolic steroid use. Researchers: Dickerman RD, Schaller F, McConathy WJ Department of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, Tex., USA. Source: Cardiology 1998 Oct;90(2):145-8 Summary: Researchers examined 4 elite resistance-trained athletes by two-dimensional echocardiography. In addition, they […]
Growing Beyond What Nature Intended Part 3 – Steroid Synergy with GH, IGF-1, Insulin, and Thryoid
The Feasibility of Using GH, IGF-1, Insulin, and Thryoid to Enhance the Anabolic Effects of Androgens Warning: The following information is intended only as a hypothetical consideration of ways in which human physiology may be altered, through pharmacological means, to achieve striking muscularity. The drugs discussed in this series of articles are, by and large, […]