Does T3 decompose in alcohol solutions?

[master.on]

I understand that dosing liquid T3 can be troublesome, even dangerous

but
Does T3 decompose in alcohol solutions?
What if the alcohol contains some water, like Everclear?
If it does, is decomposition slow or fast? How fast?

Besides inaccurate dosing
Why are liquid T3 solutions considered unreliable?

 

[XKawN]

I've tried t3 in about as pure alcohol as you can get. I think it was 99.8% pure. Did not work. Crazy stuff. I'm very experienced in brewing. When I tried t3 I had a nomex suit on, goggles and (couldn't find my mask) had a shirt tied around my nose and mouth. Was very careful with brewing the t3 yet still felt like I was gonna die for a few weeks. That shit is no joke. Must have gotten some vapors on my skin or vapors through the shirt into my respiratory. Be very fucking careful.

 

[master.on]

I've tried t3 in about as pure alcohol as you can get. I think it was 99.8% pure. Did not work. Crazy stuff. I'm very experienced in brewing. When I tried t3 I had a nomex suit on, goggles and (couldn't find my mask) had a shirt tied around my nose and mouth. Was very careful with brewing the t3 yet still felt like I was gonna die for a few weeks. That shit is no joke. Must have gotten some vapors on my skin or vapors through the shirt into my respiratory. Be very fucking careful.

Thanks for your reply

What did you mean by did not work?
Do you think the T3 raws were legit?
Did anyone else try the T3 liquid you brewed? What did they say?

Did you get hyperthyroid symptoms from brewing it?
I agree this is very dangerous to brew, perhaps only second to clen
Even inhaling a little airborne powder can land you in an hospital, I've heard.

 

[XKawN]

In the alcohol it didn't go in to a solution. It stayed a suspension no matter what the ratio. I only purchased a gram with an order I placed for other items. Wanted to give it a try. I have access to the purest of ethanol. Wouldn't work. As for the symptoms, I don't exactly remember them. I remember I was actually worried I was gonna die. My heart, head and respiratory were fucked up. Can't remember exactly what they were doing. I just told myself I ain't doing the t3 thing again. Maybe things would have been different if I had my gas mask. That's all I remember.

 

[master.on]

In the alcohol it didn't go in to a solution. It stayed a suspension no matter what the ratio. I only purchased a gram with an order I placed for other items. Wanted to give it a try. I have access to the purest of ethanol. Wouldn't work. As for the symptoms, I don't exactly remember them. I remember I was actually worried I was gonna die. My heart, head and respiratory were fucked up. Can't remember exactly what they were doing. I just told myself I ain't doing the t3 thing again. Maybe things would have been different if I had my gas mask. That's all I remember.

I've heard you'd need a TUB of Everclear to fully dissolve a gram of T3.
The respirator mask is a great idea.
Again, tnx for the reply

 

[Megadick3000]

In the alcohol it didn't go in to a solution. It stayed a suspension no matter what the ratio. I only purchased a gram with an order I placed for other items. Wanted to give it a try. I have access to the purest of ethanol. Wouldn't work. As for the symptoms, I don't exactly remember them. I remember I was actually worried I was gonna die. My heart, head and respiratory were fucked up. Can't remember exactly what they were doing. I just told myself I ain't doing the t3 thing again. Maybe things would have been different if I had my gas mask. That's all I remember.

So what do you recommend for Dissolving T3 in? Since ethanols a no go, im curious what people are putting it in? Propylene glycol? PEG400? Water?

 

[master.on]

So what do you recommend for Dissolving T3 in? Since ethanols a no go, im curious what people are putting it in? Propylene glycol? PEG400? Water?

Bump

 

[XKawN]

Bump

I only bought a small amount. Brewed it in ethanol (very pure high grade ethanol I got from work) and used it all so I wasn't able to play around. I tried adding more and more ethanol to dilute it and it never went in to solution. That was the extent of my trial and error. I can't tell you what base it needs for a solution. If I had more I might mess around with it more. I would just make damn sure I suited up better and I was more careful. Having been doing this as long as I've been doing it I may have got a little cocky, or loose. What I really want is some raws clenbuterol. I'd like to find that, but stimulants are getting very hard to find.

 

[master.on]

I only bought a small amount. Brewed it in ethanol (very pure high grade ethanol I got from work) and used it all so I wasn't able to play around. I tried adding more and more ethanol to dilute it and it never went in to solution. That was the extent of my trial and error. I can't tell you what base it needs for a solution. If I had more I might mess around with it more. I would just make damn sure I suited up better and I was more careful. Having been doing this as long as I've been doing it I may have got a little cocky, or loose. What I really want is some raws clenbuterol. I'd like to find that, but stimulants are getting very hard to find.

Was it pure T3, from a reputable source?
I've heard you'd need a full bathtub or even a tanker to dissolve a full T3 gram, and I'm not exaggerating.

 

[XKawN]

Pure t3. You wouldn't need that much. Just simple math. 50mcg per ml would be 20,000ml per 1 gram which would be just under 6 gallons per gram.

 

[master.on]

Pure t3. You wouldn't need that much. Just simple math. 50mcg per ml would be 20,000ml per 1 gram which would be just under 6 gallons per gram.

Hmmm, let's see
1 mcg = 1/1000th of a mg
1 mg = 1/1000th of a g
so 1 g = one million mcgs
one million divided by 50 = 20,000 ml = 20 Liters of very pure alcohol
And I think real T3 solubility is even less, waaay less than 50 mcg/ml
So the bathtub ballpark figure wasn't exaggerated after all.

Still, Interesting reply XKawn. This got me scratching my head.

 

[Roco Bama]

Don't ever mess with raw t3 or clen. Btw when it comes to thyroid meds, pharma grade is the way to go. I'm currently taking Mexican brand Cynomel and t4. Pharma grade is def better than rc grade

 

[Megadick3000]

Ive got 1 gram of T3 sodium salt powder sitting around. Looking to dissolve it, was going to use ethanol but apparently thats not the answer. Maybe ill just have to sacrifice some for the sake of experimentation with a variety of different solvents and see what works.

Using 20L of ethanol is a no go for sure. Ive got propylene glycol, glycerin, DMSO, PEG400, trimethylene glycol, methanol, ethanol, and some other things in my lab. Wait, maybe ill research this through scientific channels...


T3 (sodium salt) is supplied as a crystalline solid. A stock solution may be made by dissolving the T3 (sodium salt) in the solvent of choice. T3 (sodium salt) is soluble in organic solvents such as DMSO and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of T3 (sodium salt) in these solvents is approximately 1 and 0.25 mg/ml, respectively.

T3 (sodium salt) is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, T3 (sodium salt) should first be dissolved in DMF and then diluted with the aqueous buffer of choice. T3 (sodium salt) has a solubility of approximately 0.5 mg/ml in a 1:1 solution of DMFBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.

***

Thank you for your question.

We recommend dissolving in DMSO. At room temperature, it is soluble up to 100 mg/ml. In water and ethanol, its solubility is 1 mg/ml. It is also soluble in a 1:4 mixture of HCl:EtOH at 10 mg/ml.

Please contact Technical Service if you have further questions concerning this product.

***

Soluble in water (partly miscible), dilute alkalies, 1 M HCl:EtOH (1:4) (10 mg/mL), DMSO, 100 mM NaOH (10 mg/ml), 4 M NH4OH in methanol (5 mg/ml), 1 N HCl : Alcohol mixture (1 : 2), 50% Ammonium hydroxide (20 mg/ml - clear, brown solution), 1 N Sodium hydroxide, alcohol (slightly), and ethanol 96% v/v (slightly). Practically insoluble in most other organic solvents.

***

Sooooooo it looks like DMSO is the winner for T3 (sodium salt). Its important to note this is for sodium salt, if you had freebase it may not apply. Is DMSO safe to ingest orally i wonder? I know its great for transdermal. *googles*

Answer: yes it is safe for oral use. But how safe? According to wikipedia its safer than ethanol for the LD50: DMSO is a non-toxic solvent with a median lethal dose higher than ethanol (DMSO: LD50 Oral-Rat-14,500 mg/kg,[31] Ethanol: LD50 Oral-Rat-7,060 mg/kg [32]).

Things to note: DMSO in your eye will blind you, so definitely wear eye protection although that should be a given for anything. Gloves too, obviously.

 

[master.on]

Ive got 1 gram of T3 sodium salt powder sitting around. Looking to dissolve it, was going to use ethanol but apparently thats not the answer. Maybe ill just have to sacrifice some for the sake of experimentation with a variety of different solvents and see what works.

Using 20L of ethanol is a no go for sure. Ive got propylene glycol, glycerin, DMSO, PEG400, trimethylene glycol, methanol, ethanol, and some other things in my lab. Wait, maybe ill research this through scientific channels...


T3 (sodium salt) is supplied as a crystalline solid. A stock solution may be made by dissolving the T3 (sodium salt) in the solvent of choice. T3 (sodium salt) is soluble in organic solvents such as DMSO and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of T3 (sodium salt) in these solvents is approximately 1 and 0.25 mg/ml, respectively.

T3 (sodium salt) is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, T3 (sodium salt) should first be dissolved in DMF and then diluted with the aqueous buffer of choice. T3 (sodium salt) has a solubility of approximately 0.5 mg/ml in a 1:1 solution of DMFBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.

***

Thank you for your question.

We recommend dissolving in DMSO. At room temperature, it is soluble up to 100 mg/ml. In water and ethanol, its solubility is 1 mg/ml. It is also soluble in a 1:4 mixture of HCl:EtOH at 10 mg/ml.

Please contact Technical Service if you have further questions concerning this product.

***

Soluble in water (partly miscible), dilute alkalies, 1 M HCl:EtOH (1:4) (10 mg/mL), DMSO, 100 mM NaOH (10 mg/ml), 4 M NH4OH in methanol (5 mg/ml), 1 N HCl : Alcohol mixture (1 : 2), 50% Ammonium hydroxide (20 mg/ml - clear, brown solution), 1 N Sodium hydroxide, alcohol (slightly), and ethanol 96% v/v (slightly). Practically insoluble in most other organic solvents.

***

Sooooooo it looks like DMSO is the winner for T3 (sodium salt). Its important to note this is for sodium salt, if you had freebase it may not apply. Is DMSO safe to ingest orally i wonder? I know its great for transdermal. *googles*

Answer: yes it is safe for oral use. But how safe? According to wikipedia its safer than ethanol for the LD50: DMSO is a non-toxic solvent with a median lethal dose higher than ethanol (DMSO: LD50 Oral-Rat-14,500 mg/kg,[31] Ethanol: LD50 Oral-Rat-7,060 mg/kg [32]).

Things to note: DMSO in your eye will blind you, so definitely wear eye protection although that should be a given for anything. Gloves too, obviously.

20 L alcohol LMAO!
But that would work for binge drinkers

DMSO might work but I'd still dilute it a lot.
Stay away from drop measurement. They aren't accurate and you may end up in a hospital with a racing heart rate. T3 ain't no joke.

Does 50% Ammonium Hydroxide even exists?
No it does't:
At 15.6 °C (60.1 °F), the density of a saturated solution is 0.88 g/ml and contains 35% ammonia by mass, 308 g/l w/v, (308 grams of ammonia per litre of solution) and has a molarity of approximately 18 mol L−1. At higher temperatures, the molarity of the saturated solution decreases and the density increases.
Ammonium hydroxide - Wikipedia

May I ask where did you get this info from?
Not saying you did a bad job researching, in fact you did great but this just isn't accurate at all.

I'm also interested in making high-quality liquid T3 as well.

 

[Megadick3000]

Came from L-3,3′,5-Triiodothyronine, Sodium Salt, CAS 55-06-1 under the technical information tab.

Id never use a dropper to measure anything. Just use a U-100 syringe to measure and then squirt it into a shot glass with some random amount of chaser in it, slam it, voila.

 

[master.on]

Some underground T3 is suspended in Polyethylene Glycol

Guru peptides
Liothyronine (T3) 200mcg per ml x 30ml - Guru Peptides

Peptides warehouse
Liothyronine (T3) 100mcg per ml x 60ml - Peptides Warehouse

Has anyone tried them?