Bloodwork on Pitavastatin + Glutathione vs Without

[Deadpool99]

All 3 bloodwork have around the same dose of injectables, no orals other than clen/t3.

Updated Bloodwork:

I have 3 sets: Pre cut, Mid-cut, Post-cut

Pre-Cut Bloodwork cycle support that changed compare to now:
- For lipids: I had used a combo of Citrus Bergmot, Plant sterols, Red rice yeast + coq10
- For liver: 1-2g nac

- Also previous bloodwork was done on a rest day, 24 hours from my training session






Mid-cut Bloodwork:
- For lipids: Only 4mg pitavasatatin, only 1-2 weeks into it
- For liver: 1-2g nac,1g tudca, 400mg sam-e

- Using high dose t3/clen, aggressive cut.
- Also previous bloodwork was done on a rest day, 24 hours from my training session




Post-cut bloodwork:
- For lipids: Only 4mg pitavasatatin for 5 weeks
- For liver: 400mg Glutathione IM + 1g nac

- Blood test done during training session split, not rest day, which may cause slight elevations

Notes on GGT: Only did 2, one as a natural, one currently






Natty GGT:

Marker	Pre-Cut (No pita, Nac only)	Mid-Cut (2 weeks on Pita 4mg, Tudca/Nac/Sam-e)	Post-Cut (4mg Pita, Nac, Gluta 400mg)
Total Cholesterol	70	92	77
LDL-C	32	54	41
HDL-C	24	27	21
Triglycerides	49	57	68
AST (SGOT)	46	72	72
ALT (SGPT)	66	73	112
eGFR	105	114	121

 

[Deadpool99]

@Photon @Ghoul

I am interested on ur thoughts.

For Pita:

I got similar lipid values regardless of using it, do u think I should suspect my Indian pita or wait more time? 5 Weeks seems a good amount of time to assess. I was mainly looking for the HDL increase. @Ghoul.

I had all time low liver enzymes mid-cut when using nac/tudca/sam-e. Lower than my natural liver values, even during an aggressive cut of 1300 calories + 120-160mcg clen + 80mcg t3.

However 4 weeks on Glutathione 400mg yielded same values I had before adding tudca/sam-e. So do u feel like I'm doing smth wrong @Photon?

 

[Ghoul]

The numbers are what I’d expect.

The 3 supplement combo comes close to the LDL reduction Pita 4 is expected to achieve, so you swapped the combo for the roughly equivalent efficacy of Pitavastatin.

But that’s not the only thing to consider.

Supplements like citrus bergamot, plant sterols, and red yeast rice are unreliable. Red yeast rice IS a statin, but the very worst type with major off target effects. As a supplement that’s completely unregulated doses can and do vary wildly. When tests are performed, some batches have been found to be are contaminated, and it can still cause muscle or liver problems matching the rate of the worst 1st gen statins, a risk that grows with long term use as the compounds accumulate in your tissues. The EU has moved to ban it. The European Society of Cardiology said they found no reduction in heart attacks and strokes despite the cholesterol reduction. It also lacks proven anti-inflammatory effects what are a critical part of cardiovascular risk reduction.

Pitavastatin, by contrast, is a precisely dosed, “sniper rifle” molecule with a very low incidence of side effects, strong anti-inflammatory benefits, and clearly proven reduction in heart attacks, strokes, and overall cardiovascular risk. Its effects are predictable and manufacturing monitored, making it far safer and more effective than any supplement.

I suspect the cost of Pita is close to the combined 3 supplements.

So that single pill will reliably keep your cardiovascular system in good shape (hopefully HDL will recover over the next few weeks), with minimal risk of sides.

Doing a great job by the way. Your arteries will never be in as good shape as they are now, and your current numbers will keep them that way.

I would get Lipoprotein A checked, it’s crucial.

Also HS-CRP, to make sure vascular inflammation isn’t a problem.

 

[Deadpool99]

The numbers are what I’d expect.

The 3 supplement combo comes close to the LDL reduction Pita 4 is expected to achieve, so you swapped the combo for the roughly equivalent efficacy of Pitavastatin.

But that’s not the only thing to consider.

Supplements like citrus bergamot, plant sterols, and red yeast rice are unreliable. Red yeast rice IS a statin, but the very worst type with major off target effects. As a supplement that’s completely unregulated doses can and do vary wildly. When tests are performed, some batches have been found to be are contaminated, and it can still cause muscle or liver problems matching the rate of the worst 1st gen statins, a risk that grows with long term use as the compounds accumulate in your tissues. The EU has moved to ban it. The European Society of Cardiology said they found no reduction in heart attacks and strokes despite the cholesterol reduction. It also lacks proven anti-inflammatory effects what are a critical part of cardiovascular risk reduction.

Pitavastatin, by contrast, is a precisely dosed, “sniper rifle” molecule with a very low incidence of side effects, strong anti-inflammatory benefits, and clearly proven reduction in heart attacks, strokes, and overall cardiovascular risk. Its effects are predictable and manufacturing monitored, making it far safer and more effective than any supplement.

I suspect the cost of Pita is close to the combined 3 supplements.

So that single pill will reliably keep your cardiovascular system in good shape (hopefully HDL will recover over the next few weeks), with minimal risk of sides.

Doing a great job by the way. Your arteries will never be in as good shape as they are now, and your current numbers will keep them that way.

I would get Lipoprotein A checked, it’s crucial.

Also HS-CRP, to make sure vascular inflammation isn’t a problem.

Will do, I can draw blood tomorrow.

Any other blood test I should need? Rest of my CBC/CMP is normal
- Stack is 825mg test, 720mg tren, 480mg mast, 6ius hgh, 15mg reta, 4.5mg cagri

Pita is def cheaper, I went with pita mainly for 4 reasons:
- Consistent qulaity control
- Lower pills count (8 pills vs 1 pill)
- Cheaper $28 + tax vs $15
- Most likely more effective and probably going to be more beneficial long term

 

[220]

Will do, I can draw blood tomorrow.

Any other blood test I should need? Rest of my CBC/CMP is normal
- Stack is 825mg test, 720mg tren, 480mg mast, 6ius hgh, 15mg reta, 4.5mg cagri

Pita is def cheaper, I went with pita mainly for 4 reasons:
- Consistent qulaity control
- Lower pills count (8 pills vs 1 pill)
- Cheaper $28 + tax vs $15
- Most likely more effective and probably going to be more beneficial long term

Thanks for the wisdom.

 

[Elektrobot]

Will do, I can draw blood tomorrow.

Any other blood test I should need? Rest of my CBC/CMP is normal
- Stack is 825mg test, 720mg tren, 480mg mast, 6ius hgh, 15mg reta, 4.5mg cagri

Pita is def cheaper, I went with pita mainly for 4 reasons:
- Consistent qulaity control
- Lower pills count (8 pills vs 1 pill)
- Cheaper $28 + tax vs $15
- Most likely more effective and probably going to be more beneficial long term

How did you get your pita prescription?

 

[Deadpool99]

How did you get your pita prescription?

Indian pharma

 

[Elektrobot]

Indian pharma

I might have to go to there

I was on my way to getting a pita insurance approval, but then my cardiologist ordered bloodwork and my creatine kinease was super elevated, likely from training. He told me to stop all statins and wrote me a script for repatha

So now I'm waiting on insurance to agree with that

I'm thrilled to hopefully have repatha, but I'd still like to incorporate pita

 

[Ghoul]

I might have to go to there

I was on my way to getting a pita insurance approval, but then my cardiologist ordered bloodwork and my creatine kinease was super elevated, likely from training. He told me to stop all statins and wrote me a script for repatha

So now I'm waiting on insurance to agree with that

I'm thrilled to hopefully have repatha, but I'd still like to incorporate pita

Repatha is a BIG win. Pita is easy. Telehealth or India Pharma.

 

[Ghoul]

Thanks for the wisdom.

I had no idea how bad the red yeast rice is for the liver. It’s flat out hepatoxic. No wonder the EU is banning it.

 

[Photon]

Pre-Cut Bloodwork cycle support that changed compare to now:
- For liver: 1-2g nac
- Also previous bloodwork was done on a rest day, 24 hours from my training session

Mid-cut Bloodwork:
- For liver: 1-2g nac,1g tudca, 400mg sam-e
- Using high dose t3/clen, aggressive cut.
- Also previous bloodwork was done on a rest day, 24 hours from my training session

Post-cut bloodwork:
- For liver: 400mg Glutathione IM + 1g nac
- Blood test done during training session split, not rest day, which may cause slight elevations

Notes on GGT: Only did 2, one as a natural, one currently
Natty GGT:

Marker	Pre-Cut (No pita, Nac only)	Mid-Cut (2 weeks on Pita 4mg, Tudca/Nac/Sam-e)	Post-Cut (4mg Pita, Nac, Gluta 400mg)
Total Cholesterol	70	92	77
LDL-C	32	54	41
HDL-C	24	27	21
Triglycerides	49	57	68
AST (SGOT)	46	72	72
ALT (SGPT)	66	73	112
eGFR	105	114	121

Dam your ALT is horrendous even pre-cut.
Do you have NAFLD?

Pull CMP again on a rest day.

 

[Deadpool99]

I had no idea how bad the red yeast rice is for the liver. It’s flat out hepatoxic. No wonder the EU is banning it.

I just realized as I increase my tren, my eGFR increases, lol.

 

[Elektrobot]

Repatha is a BIG win. Pita is easy. Telehealth or India Pharma.

I have a prescription sitting at cvs that could be filled. Was just waiting for insurance to do it.

I might just transfer it to costplus and fill it there

 

[Photon]

I'm thrilled to hopefully have repatha, but I'd still like to incorporate pita

Just ask for it.
I mean if she's willing to give repatha, i don't see why she wouldn't give a statin..

 

[Ghoul]

Will do, I can draw blood tomorrow.

Any other blood test I should need? Rest of my CBC/CMP is normal
- Stack is 825mg test, 720mg tren, 480mg mast, 6ius hgh, 15mg reta, 4.5mg cagri

Pita is def cheaper, I went with pita mainly for 4 reasons:
- Consistent qulaity control
- Lower pills count (8 pills vs 1 pill)
- Cheaper $28 + tax vs $15
- Most likely more effective and probably going to be more beneficial long term

Coq10 if you haven’t checked before.

Some people are poor Ubiquinone → Ubiquinol converters.

I don’t know which form you’re taking, but if Ubiquinone, and it isn’t converting efficiently, you’ll want to switch to Ubiquinol since any statin can cause a deficiency, impairing mitochondrial function.

Pita does this the least, but still, you’re putting more demand on Coq10 than a sedentary person.

As for other tests, TSH FT4 FT3. When messing with thyroid I like to keep a close eye on it.

A1C - because on GH it can sneakily get worse.

Lipids in a month.

 

[Elektrobot]

I just realized as I increase my tren, my eGFR increases, lol.

Do you know what your igf-1 is when you aren't in a deficit?

 

[Deadpool99]

Dam your ALT is horrendous even pre-cut.
Do you have NAFLD?

Pull CMP again on a rest day.

For reference my natty AST/ALT were always 55/75. Ofc no supplementation.

Do you know what your igf-1 is when you aren't in a deficit?

sadly I don’t, however I will be following my IGF1 as I bulk.

 

[Ghoul]

I have a prescription sitting at cvs that could be filled. Was just waiting for insurance to do it.

I might just transfer it to costplus and fill it there

With the Repatha copay card, I have it filled mail order, 3 months at a time for $25 (have him resubmit the prescription as 3 months mentioning it’s much cheaper for you that way).

Amgen® SupportPlus Enrollment | Repatha® (evolocumab)

Enroll in Amgen® SupportPlus to access financial support and helpful resources to help you through your Repatha® treatment. See Full Prescribing & Safety Info.

www.repatha.com

 

[Deadpool99]

Coq10 if you haven’t checked before.

Some people are poor Ubiquinone → Ubiquinol converters.

I don’t know which form you’re taking, but if Ubiquinone, and it isn’t converting efficiently, you’ll want to switch to Ubiquinol since any statin can cause a deficiency, impairing mitochondrial function.

Pita does this the least, but still, you’re putting more demand on Coq10 than a sedentary person.

As for other tests, TSH FT4 FT3. When messing with thyroid I like to keep a close eye on it.

A1C - because on GH it can sneakily get worse.

Lipids in a month.

I stopped taking Ubiq, is it true that I need to be taking fat alongside it? If so, how much? I’ve read that without fat it doesn’t get absorbed but I haven’t dug deep to see if it’s rly trye

A1C at 5.0

Will re-take thyroid after 8 weeks from cutting off t3 and supplementing with t4 to see how my thyroid is taking it

 

[Elektrobot]

Just ask for it.
I mean if she's willing to give repatha, i don't see why she wouldn't give a statin..

My creatine kinase was 773 on my last labs. They put in my chart to discontinue statins.