I understand that one of Metformin's mechanisms of action is the activation of AMPK and thus inhibition of mTOR, which theoretically could attenuate muscular adaptations to resistance training (i.e. blunting muscle hypertrophy). I also understand that Metformin has a potentially suppressive...
Metformin: Risk vs. Reward Profile
Author: Type-IIx
Here are the basic contours of risks versus rewards for the practical use of Metformin, a biguanide, for bodybuilding, that I will build out with more depth and breadth if readers want to delve deeper:
Metformin: anti-hyperglycemic and an...
Just coming off a PCT after a 15 week cycle of Test E, NPP and Mast E but sitting at relatively high body weight. Next I am looking to get lean as possible, keeping as much gains from the cycle as i can.
I am thinking of 20 weeks "shred" cycle and looking at stacking 1mg Semaglutide a week and...
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