0.45 filters are sufficient ?

Biggerp73

Member
Doing some research and I'm seeing scientists say that 0.45 micron filters are basically sufficient, and that while 0.2 & 0.22 micron filters are better, not even they can guarantee complete removal of all bacteria. Interestingly, scientists believed 0.45 was sufficient to guarantee complete sterility up until ~1994 when they discovered brevundimonas diminuta, a strain of bacteria small enough to get through. Which means injectable medicines produced before that time were never filtered with anything better than 0.45 micron filters
 
Doing some research and I'm seeing scientists say that 0.45 micron filters are basically sufficient, and that while 0.2 & 0.22 micron filters are better, not even they can guarantee complete removal of all bacteria. Interestingly, scientists believed 0.45 was sufficient to guarantee complete sterility up until ~1994 when they discovered brevundimonas diminuta, a strain of bacteria small enough to get through. Which means injectable medicines produced before that time were never filtered with anything better than 0.45 micron filters
I am interested if you have any info on any of this. When filtering by hand, these .22 filters are a PITA.

@JetsFan I totally understand your point of view, but if there is a simpler way, why not investigate? I know you're one of the resident experts of homebrewing, but I'd still like to get whatever info is out there
 
I am interested if you have any info on any of this. When filtering by hand, these .22 filters are a PITA.

@JetsFan I totally understand your point of view, but if there is a simpler way, why not investigate? I know you're one of the resident experts of homebrewing, but I'd still like to get whatever info is out there

Filtering with syringe filters by hand is indeed a PITA that's where a caulking gun comes into play. Yes it's a bit slow, but it's better than an abcess....now that's a real PITA, literally ;)
 
I am interested if you have any info on any of this. When filtering by hand, these .22 filters are a PITA.

@JetsFan I totally understand your point of view, but if there is a simpler way, why not investigate? I know you're one of the resident experts of homebrewing, but I'd still like to get whatever info is out ther
Just play it safe and use .22

Yeah so it's probably best to play it safe with a 0.2 or 0.22, especially if you are able to use a pump and a bottle top filter which makes it easy

As far as info, heres a link.. Defining a Pore Size and Sterile Filtering; 0.2 Micron vs. 0.22 Micron. What’s the difference?


"Before 0.2 and 0.22 micron filters became standard, it was thought that filters with an absolute rating of 0.45 micron were thought to be sufficient to strain out even the smallest bacteria. However, the discovery of Brevundimonas diminuta, showed that there were still bacteria capable of passing through a 0.45 micron filter in large quantities."


Also, the conversation on this reddit post in the comments is interesting..


View: https://amp.reddit.com/r/askscience/comments/14iaof/why_is_a_022_micron_pore_size_considered_tight/
 
Yeah so it's probably best to play it safe with a 0.2 or 0.22, especially if you are able to use a pump and a bottle top filter which makes it easy

As far as info, heres a link.. Defining a Pore Size and Sterile Filtering; 0.2 Micron vs. 0.22 Micron. What’s the difference?


"Before 0.2 and 0.22 micron filters became standard, it was thought that filters with an absolute rating of 0.45 micron were thought to be sufficient to strain out even the smallest bacteria. However, the discovery of Brevundimonas diminuta, showed that there were still bacteria capable of passing through a 0.45 micron filter in large quantities."


Also, the conversation on this reddit post in the comments is interesting..


View: https://amp.reddit.com/r/askscience/comments/14iaof/why_is_a_022_micron_pore_size_considered_tight/



I've used .22 forever now with zero issues so I guess it's personal choice really, but I see no reason for me to switch from .22 to .45.

Cheers :cool:
 
Nah, after reading through a little bit of that stuff, it made me feel like .22 is the way to go. Sure .45 is good enough for some things, but for an added layer of protection, I'll just stick with these (still a pain in the ass) .22 filters lol
 
Nah, after reading through a little bit of that stuff, it made me feel like .22 is the way to go. Sure .45 is good enough for some things, but for an added layer of protection, I'll just stick with these (still a pain in the ass) .22 filters lol
It's definitely safer that way I just think if medical products were made using 0.45 micron up until 1994, it's probably sufficient most of the time
 
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