Anyone run SS-31

I am obviously really just guessing, and leaving aside that MB might boost the efficacy of SS-31, but at 40 days I would not expect a long term repair effect of SS-31 yet.
Do you feel like there is, or at least was, a lasting effect after you ended the 40 daycycle of SS-31? Because what you describe otherwise is not far off from how I would describe the effect of 10-15mg of MB alone.
TBH, I didnt feel like it was a lasting effect. But maybe I didn’t run it long enough. This time I’m going to run it for at least 100 days and possibly longer depending on how it goes during the 100 days. I just reconned the first vial and will start tomorrow. I saw a news report on this kid that has Barth Syndrome that is using it. Not sure what his daily dose was but according to him and his mother he was down really bad and couldnt hardly leave the house to him going outside and doing all types activities like cycling, soccer and basketball. So no doubt, it works. Just not sure what it does for us without that issue. I was really happy to see an actual real world case where this kid had such a great life changing improvement.
 
TBH, I didnt feel like it was a lasting effect. But maybe I didn’t run it long enough. This time I’m going to run it for at least 100 days and possibly longer depending on how it goes during the 100 days. I just reconned the first vial and will start tomorrow. I saw a news report on this kid that has Barth Syndrome that is using it. Not sure what his daily dose was but according to him and his mother he was down really bad and couldnt hardly leave the house to him going outside and doing all types activities like cycling, soccer and basketball. So no doubt, it works. Just not sure what it does for us without that issue. I was really happy to see an actual real world case where this kid had such a great life changing improvement.
I would assume that kid took 40mg a day, based on the studies discussed in the previous posts of @gainslol and me. Keep in mind mitochondrial function can apparently be down by 95% in Barth-syndrome-patients. I would not assume more than 15-20%, in severe cases *maybe* 30%, of reduction for someone being able to live an active life and being decently athletic.

If you haven't started the run yet, maybe consider running the SS-31 as hypothesised by me in the above posts? I would be super curious what you will report back to us!
I currently can't afford a run of 1000mg (or more) of SS-31, so I will leave my 10*50mg kit in the freezer for now.

What was and will be your MB dose in the first and second run?
 
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I would assume that kid took 40mg a day, based on the studies discussed in the previous posts of @gainslol and me. Keep in mind mitochondrial function can apparently be down by 95% in Barth-syndrome-patients. I would not assume more than 15-20%, in severe cases *maybe* 30%, of reduction for someone being able to live an active life and being decently athletic.

If you haven't started the run yet, maybe consider running the SS-31 as hypothesised by me in the above posts? I would be super curious what you will report back to us!
I currently can't afford a run of 1000mg (or more) of SS-31, so I will leave my 10*50mg kit in the freezer for now.

What was and will be your MB dose in the first and second run?
I will take a look at your protocol. My MB will be 20mg. You have a suggested dosing protocol for MB?
 
Here is the post with my write up.
SS-31 Journey
Thanks, will read it when I get to it!

I will take a look at your protocol. My MB will be 20mg. You have a suggested dosing protocol for MB?
Keep in mind, the idea for this high peak and then slow tapering off is hypothetical and speculative based on assumptions, but you will be able to read up on my reasoning, starting at this post.

Regarding the MB, not really. I was not able to even remotely correlate the of MB to SS-31, other than it could perhaps increase the efficacy of the mitochondrial repair process.
AFAIR the general recommendations seem to be to stay below 15mg, but YMMV. I tried up to 23mg, but I felt like I was on a stimulant. Didn't like it and had a hard time to shut it down in the evening. Around 13mg is my sweet spot.
 
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Thanks, will read it when I get to it!


Keep in mind, the idea for this high peak and then slow tapering off is hypothetical and speculative based on assumptions, but you will be able to read up on my reasoning, starting at this post.

Regarding the MB, not really. I was not able to even remotely correlate the of MB to SS-31, other than it could perhaps increase the efficacy of the mitochondrial repair process.
AFAIR the general recommendations seem to be to stay below 15mg, but YMMV. I tried up to 23mg, but I felt like I was on a stimulant. Didn't like it and had a hard time to shut it down in the evening. Around 13mg is my sweet spot.
I am very sensitive to stimulants as well. I will consider going with a smaller dose of the MB. I will your post now and see your thoughts behind your dosing protocol.
 
I am very sensitive to stimulants as well. I will consider going with a smaller dose of the MB. I will your post now and see your thoughts behind your dosing protocol.
I start at around 4mg and then escalated the dose by 1-2mg every few days, until I felt comfortable with the dose at around 13mg.
I then went up higher, but felt as described and went back to the dose I deemed to be optimal.
 
I start at around 4mg and then escalated the dose by 1-2mg every few days, until I felt comfortable with the dose at around 13mg.
I then went up higher, but felt as described and went back to the dose I deemed to be optimal.
I was looking at maz and saw that you are using it. I’m going to go over to your post and ask my questions.

Sorry mixed you and @bananafeet with each other.
 
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I ran ss-31 for 2 months on the second run, was planning on running longer but life happened and I got off track, my highest dose was 16.5mg.
Given your sex, is it safe to assume that the equivalent dose to your 16.5mg would be quite a bit higher for me at 90-100kg, let alone even heavier men?

I had a look at your thread, but my I still couldn't really say what the outcome of your 2 runs of SS-31 was.
You mention weight loss and not feeling well (during the 1st run?) because you didn't think of adding a methyl donor.
Did you overall performance increase in some way, can you quantify it in a way like being able to run faster or for longer, being stronger, etc.?

I was looking at maz and saw that you are using it. I’m going to go over to your post and ask my questions.

Sorry mixed you and @bananafeet with each other.
No worries, the guy is just trying to ride the Banana brand name, that I have so successfully established. But you can be assured, that there is and only will ever be one @Banana Joe !
I still can't make out what you could mean with "maz", maybe MB?!
 
Given your sex, is it safe to assume that the equivalent dose to your 16.5mg would be quite a bit higher for me at 90-100kg, let alone even heavier men?

I had a look at your thread, but my I still couldn't really say what the outcome of your 2 runs of SS-31 was.
You mention weight loss and not feeling well (during the 1st run?) because you didn't think of adding a methyl donor.
Did you overall performance increase in some way, can you quantify it in a way like being able to run faster or for longer, being stronger, etc.?


No worries, the guy is just trying to ride the Banana brand name, that I have so successfully established. But you can be assured, that there is and only will ever be one @Banana Joe !
I still can't make out what you could mean with "maz", maybe MB?!
Maz= Mazdutide. It’s a GLP-1
 
Thanks for the report.
Do you have blood work, to support the assumption your mitochondria work better afterwards? And can give a rough estimate, even if it just feelz, how long that effects lasts, before you have to repeat the cycle.

No bloods specifically for this sadly. I left a 3 month gap from my previous cycle and I would say the effect from this one wasn't as apparent as the first one so maybe some benefit was already still present 3 months later
 
I’m on the last week of a 4-week run SS-31, first 3 weeks at 4mg/d and this last week at 8mg/d. Following this protocol that’s been passed around which includes NAD+ and MOTS-C.

Started it right after a DNP run to see if it would help heal some of the mitochondrial damage, and I’m pretty happy with the results so far.

Excited to see how MOTS-C works out - will try to remember to post an update after a few weeks on that.
So it seems like SS-31 + MOTS-c really did help restore my energy levels after I was feeling fatigued from a DNP run. About a week after I stopped the SS-31 and started MOTS-c, I was back to doing rest pause / drop sets whereas before I was having trouble even finishing a session.

MOTS-c I ran at 10mg 2x/week, then 5mg 3x/week, and now doing 2mg/day. I don't feel that immediate burst of energy from it that some people report, so it could also be that most of the benefit I got was from SS-31.

Will definitely keep this protocol in my back pocket.
 
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