Axl
New Member
Hi,
Take a look at this. Some of us have asked themselves how many times they should inject. This text seems to give the answer to that.
QUOTE:
"Long chain esters of anabolic steroids are not many more times potent than short chain, if indeed they are any more potent at all. Yet in the above study, the undecanoate ester was found to give 3.5 times the effect of the propionate ester. Why?
There is a difference in pharmacokinetics (the time course of the drug in the body). Although the same 1 mg dose is being given in each case, it is either present in the serum of the animal at a relatively high concentration for a relatively short time for the shorter chain esters, or at lower concentration for a longer time for the longer chain esters. This difference can be quite large: the undecanoate ester can be predicted to have a half-life 36 times longer than that of the propionate ester.3
With most drugs, response is not proportional to the dose, but to the log of the dose. Assuming that the dose is well into the effective range, taking the dose does not result in only the result, but in the result.
.....
This correlates with my observation that anabolic effect of testosterone esters is equal, so long as each is administered reasonably frequently: at least once per half-life, and preferably twice. (!!!!!!!!!!!!!) E.g., if testosterone propionate yielding some given amount of testosterone per week is administered daily, or at least every other day, it will give results comparable to testosterone cypionate administered at least once every week, and preferably twice per week, that yields the same amount of testosterone per week.
....
Testosterone cypionate has a half-life of 8 days5, the enanthate ester has a half-life of 4 days6, and nandrolone decanoate has a half-life of 8 days7. These figures are only approximate. The difference between these values for cypionate and enanthate probably includes difference attributable to different measuring techniques. The actual difference is probably not more than two days."
UNQUOTE
Source:
https://thinksteroids.com/articles/anabolic-steroid-esters/
Take a look at this. Some of us have asked themselves how many times they should inject. This text seems to give the answer to that.
QUOTE:
"Long chain esters of anabolic steroids are not many more times potent than short chain, if indeed they are any more potent at all. Yet in the above study, the undecanoate ester was found to give 3.5 times the effect of the propionate ester. Why?
There is a difference in pharmacokinetics (the time course of the drug in the body). Although the same 1 mg dose is being given in each case, it is either present in the serum of the animal at a relatively high concentration for a relatively short time for the shorter chain esters, or at lower concentration for a longer time for the longer chain esters. This difference can be quite large: the undecanoate ester can be predicted to have a half-life 36 times longer than that of the propionate ester.3
With most drugs, response is not proportional to the dose, but to the log of the dose. Assuming that the dose is well into the effective range, taking the dose does not result in only the result, but in the result.
.....
This correlates with my observation that anabolic effect of testosterone esters is equal, so long as each is administered reasonably frequently: at least once per half-life, and preferably twice. (!!!!!!!!!!!!!) E.g., if testosterone propionate yielding some given amount of testosterone per week is administered daily, or at least every other day, it will give results comparable to testosterone cypionate administered at least once every week, and preferably twice per week, that yields the same amount of testosterone per week.
....
Testosterone cypionate has a half-life of 8 days5, the enanthate ester has a half-life of 4 days6, and nandrolone decanoate has a half-life of 8 days7. These figures are only approximate. The difference between these values for cypionate and enanthate probably includes difference attributable to different measuring techniques. The actual difference is probably not more than two days."
UNQUOTE
Source:
https://thinksteroids.com/articles/anabolic-steroid-esters/
