Are there any studies that show how many weeks off the receptors return to normal?
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2-4 weeks at a time if you look at the PowerPoint that @Type-IIx made. It doesn't mention how long the break should be but usually time on equals time off. It's in his drop box files on his discord. Join the Gear, Growth, and Gains Hosted by Type-IIx @ Ampouletude.com Discord Server!
The fat burning stops quickly because of rapid B2AR tachyphylaxis (desensitization). Ketotifen is an adjuvant that might be used in combination with it to permit continued lipolysis but whether hypertrophy continues isn’t known because of the involvement of myostatin cross-talk that is not under B2AR control.2-4 weeks at a time if you look at the PowerPoint that @Type-IIx made. It doesn't mention how long the break should be but usually time on equals time off. It's in his drop box files on his discord. Join the Gear, Growth, and Gains Hosted by Type-IIx @ Ampouletude.com Discord Server!
I think @Ghoul mentioned you can take clen forever and it won't lose it's fat burning properties, just the shakes. And of course you would have to worry about any potential heart damage accruing over time since you aren't taking breaks to heal or minimize damage