constructing sarms

[Dema]

So I had a buddy on mine come to me cus I ran a lot of sarms asking for advice and I have no clue! I always bought my sarms online and ready to go. Well he has raw powder and he was wondering what kind of process he has to do to make it into liquid form. He asked if he could simply mix with food grade propylene glycol and be good to go? I thought that he might need to disinfect the raw powder or something before just throwing it into a liquid! Any help would be much appreciated thanks

 

[Dr JIM]

Why is he wanting to convert this powder into a liquid form?

God forbid if he is even thinking about pinning these SARMS.

I have no idea about generic or UGL grade SARMS but bc the oral bioavailability is relatively high the advantage from parenteral administration is minimal at best.

Besides that although there may be some theoretical benefit to SARMs use, their practical application as anabolic agents have yet to be proven IMO.

(I SUSPECT their primary MOA will eventually be proven to be anti-catabolic rather than anabolic)

 

[Dema]

He has raw powder and he want to make it into liquid form for oral administration!

 

[Dr JIM]

WHY?

Heck buy a pill press and use it!

 

[Dema]

Idk isn't there a reason mostly all sarms come in liquid form?

 

[Dr JIM]

From a therapeutic perspective not that I'm aware of bc it won't alter it's absorption.

 

[Dema]

anyone else have some insight as a pill press wouldn't be needed for the amount he has

 

[XKawN]

Yeah, it's better in oral liquid form if your selling to a large number of people. Not everyone will want to take the exact same amount of active ingredient. You'll have the ability to alter the dose to your liking. Your best bet is a cap-em-quick. It's easy and cost efficient.

 

[Morefyah]

Copy and pasted from another site.
Just do the math sarms should be no different.

Liquid oral recipes!!

1. 
   
   ANADROL
   Powder: per 1 gram of Oxymetholone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   1 gram of Oxymetholone powder
   1 Beaker suitable for holding the volume of liquids
   8.4ml of PEG 300
   10.5ml 190 Proof Grain Alcohol
   
   ANAVAR
   Powder: per 1 gram of Oxandrolone
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   1 gram of Oxandrolone powder
   1 beaker suitable for holding the volume of liquids
   9.8ml of PEG 300
   39.2ml of 190 Proof Grain Alcohol
   
   ARIMIDEX
   Powder: per 1 gram of Anastrozole
   Produces: Highest concentration made ***8211; 5mg/ml
   
   Requirements
   1 gram of Anastrozole powder
   1 beaker suitable for holding the volume of liquids
   19.9ml of PEG 300
   179.1ml of 190 Proof Grain Alcohol
   
   CLOMID (Version I)
   Powder: per 1 gram of Clomiphene Citrate
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   1 gram of Clomiphene Citrate
   1 beaker suitable for holding the volume of liquids
   7.6ml of Glycerol
   11.3ml of 190 Proof Grain Alcohol
   
   CLOMID (Version II)
   Powder: per 1 gram of Clomiphene Citrate
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   
   1 gram of Clomiphene Citrate
   1 beaker suitable for holding the volume of liquids
   8.4ml of PEG 600
   10.5ml of 190 Proof Grain Alcohol
   
   DIANABOL
   Powder: per 1 gram Methandrostenolone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   
   1 gram of Methandrostenolone powder
   1 beaker suitable for holding he volume of liquids
   19ml of 190 Proof Grain Alcohol
   
   FEMARA
   Powder: per 1 gram of Letrozole
   Produces: Highest concentration made ***8211; 5mg/ml
   
   Requirements:
   
   1 gram of Letrozole powder
   1 beaker suitable for holding the volume of liquids
   19.9ml of PEG 300
   179.1ml of 190 Grain Proof Alcohol
   
   NOLVADEX (Version I)
   Powder: per 1 gram of Tamoxifen Citrate
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   
   1 gram of Tamoxifen Citrate
   1 beaker suitable for holding the volume of liquids
   19.6ml of Glycerol
   29.4ml of 190 Proof Grain Alochol
   
   NOLVADEX (Version II)
   Powder: per 1 gram of Tamoxifen Citrate
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   
   1 gram of Tamoxifen Citrate
   1 beaker suitable for holding the volume of liquids
   9.8ml of PEG 600
   39.2ml of 190 Proof Grain Alcohol
   
   PROVIRON
   Powder: per 1 gram of Mesterolone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements
   
   1 gram of Mesterolone
   1 beaker suitable for holding the volume of liquids
   8.4ml of PEG 300
   10.5ml of 190 Proof Grain Alcohol
   
   WINSTROL
   Powder: per 1 gram of Stanozlol
   Produces: Highest concentration made ***8211; 25mg/ml
   
   Requirements:
   
   1 gram of Stanozlol
   1 beaker for holding the volume of liquids
   7.8ml of PEG 300
   31.2ml of 190 Proof Grain Alochol
   
   For all of the above conversions requiring PEG and 190 Proof Alcohol, use the following procedure;
   Place a sufficient amount of water in a pan and place on the stove
   Remove from heat when the water reaches boiling temperature
   Place the powder and the PEG in the beaker
   Immerse the beaker in the pan of water so that the water is level with the top of the contents of the beaker
   Gently swirl or stir the contents of the beaker until the solution is clear (reheat the water if necessary)
   Remove the beaker from the water
   Allow the PEG to cool down
   Slowly add the 190 Proof Alcohol to the mixture
   Gently stir until fully mixed.
   
   For all of the above conversions where PEG is not required, use the following procedure;
   Mix powder and 190 Proof Alcohol in the beaker
   Gently swirl or stir the contents of the beaker until the solution is clear
   The majority of powders which do not require PEG will dissolve rea dily but those that are troublesome, refer to the heating procedure as outlined above.
   In the event that 190 Grain Alcohol (EverClear) is unavailable, you could substitute Bacardi 151.
   List of Materials:
   190 Proof Grain Alcohol or Bacardi 151, PEG 300, PEG 600. Powder, beaker, stir rod, suitable container for holding finished preparation. Weighing scales accurate to 0.001g (if preparing yourself)
   
   You never want to be in a situation where you have to shake it up to use it. While it***8217;s good to shake a solution to ensure even distribution throughout the liquid, you should always prefer to have all of your powder dissolved and not to be able to see any crystals floating around in the liquid
   Ideally you want a solution, not a suspension. If you have a preparation which is little more than powder sitting in liquid, or where after swirling it visibly falls down to the bottom of the vial, it is utterly useless for getting any kind of consistency of dosing. Anything worthy of being called a suspension should be fairly stable after shaking such that you can take your time to draw it.

 

[Jimmyinkedup]

He has to look into what he has and see if they can be made into a solution or a suspension. For a solution probably they would be dissolved in ethyl alcohol (everclear 190). If they cannot be made into a solution they would have to be made into a suspension. Easiest way to do this IMO is to use something like Humco Oral Suspension Vehicle, which can be purchased online. He can probably research the compounds he has and find out the relative solubility in alcohol to see which route he would need to go. OR, as has been said, he can but a capping machine and empty caps and use something as a filler (ie protein powder) and cap them. Liquids are easier and imo more accurate than caps as you dont have to worry about even mixing filler and raw etc. Also it couldnt be easier to calculate as a liquid. Simply figure out the strength you want in mg/ml. Add the raw to a marked flask or beaker and fill to the appropriate amount.

 

[Dema]

Thanks guys for the info! This is exactly what he needed! Now let's see if he will let me sample some

 

[jp4355]

He has raw powder and he want to make it into liquid form for oral administration!

I'm pretty sure that Everclear (190 proof grain alcohol), can be used with any SARMS.
I waiting for a reply from a Source about using Bacardi 151 in lieu of Everclear.
It's not Legal in All States................................ JP
P.S.
It would be 40 Ml per 1 Gram for MK-677 to yield 25 Mg/Ml.
Not sure about the others.

 

[Dr JIM]

Copy and pasted from another site.
Just do the math sarms should be no different.

Liquid oral recipes!!

1. 
   
   ANADROL
   Powder: per 1 gram of Oxymetholone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   1 gram of Oxymetholone powder
   1 Beaker suitable for holding the volume of liquids
   8.4ml of PEG 300
   10.5ml 190 Proof Grain Alcohol
   
   ANAVAR
   Powder: per 1 gram of Oxandrolone
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   1 gram of Oxandrolone powder
   1 beaker suitable for holding the volume of liquids
   9.8ml of PEG 300
   39.2ml of 190 Proof Grain Alcohol
   
   ARIMIDEX
   Powder: per 1 gram of Anastrozole
   Produces: Highest concentration made ***8211; 5mg/ml
   
   Requirements
   1 gram of Anastrozole powder
   1 beaker suitable for holding the volume of liquids
   19.9ml of PEG 300
   179.1ml of 190 Proof Grain Alcohol
   
   CLOMID (Version I)
   Powder: per 1 gram of Clomiphene Citrate
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   1 gram of Clomiphene Citrate
   1 beaker suitable for holding the volume of liquids
   7.6ml of Glycerol
   11.3ml of 190 Proof Grain Alcohol
   
   CLOMID (Version II)
   Powder: per 1 gram of Clomiphene Citrate
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   
   1 gram of Clomiphene Citrate
   1 beaker suitable for holding the volume of liquids
   8.4ml of PEG 600
   10.5ml of 190 Proof Grain Alcohol
   
   DIANABOL
   Powder: per 1 gram Methandrostenolone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements:
   
   1 gram of Methandrostenolone powder
   1 beaker suitable for holding he volume of liquids
   19ml of 190 Proof Grain Alcohol
   
   FEMARA
   Powder: per 1 gram of Letrozole
   Produces: Highest concentration made ***8211; 5mg/ml
   
   Requirements:
   
   1 gram of Letrozole powder
   1 beaker suitable for holding the volume of liquids
   19.9ml of PEG 300
   179.1ml of 190 Grain Proof Alcohol
   
   NOLVADEX (Version I)
   Powder: per 1 gram of Tamoxifen Citrate
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   
   1 gram of Tamoxifen Citrate
   1 beaker suitable for holding the volume of liquids
   19.6ml of Glycerol
   29.4ml of 190 Proof Grain Alochol
   
   NOLVADEX (Version II)
   Powder: per 1 gram of Tamoxifen Citrate
   Produces: Highest concentration made ***8211; 20mg/ml
   
   Requirements:
   
   1 gram of Tamoxifen Citrate
   1 beaker suitable for holding the volume of liquids
   9.8ml of PEG 600
   39.2ml of 190 Proof Grain Alcohol
   
   PROVIRON
   Powder: per 1 gram of Mesterolone
   Produces: Highest concentration made ***8211; 50mg/ml
   
   Requirements
   
   1 gram of Mesterolone
   1 beaker suitable for holding the volume of liquids
   8.4ml of PEG 300
   10.5ml of 190 Proof Grain Alcohol
   
   WINSTROL
   Powder: per 1 gram of Stanozlol
   Produces: Highest concentration made ***8211; 25mg/ml
   
   Requirements:
   
   1 gram of Stanozlol
   1 beaker for holding the volume of liquids
   7.8ml of PEG 300
   31.2ml of 190 Proof Grain Alochol
   
   For all of the above conversions requiring PEG and 190 Proof Alcohol, use the following procedure;
   Place a sufficient amount of water in a pan and place on the stove
   Remove from heat when the water reaches boiling temperature
   Place the powder and the PEG in the beaker
   Immerse the beaker in the pan of water so that the water is level with the top of the contents of the beaker
   Gently swirl or stir the contents of the beaker until the solution is clear (reheat the water if necessary)
   Remove the beaker from the water
   Allow the PEG to cool down
   Slowly add the 190 Proof Alcohol to the mixture
   Gently stir until fully mixed.
   
   For all of the above conversions where PEG is not required, use the following procedure;
   Mix powder and 190 Proof Alcohol in the beaker
   Gently swirl or stir the contents of the beaker until the solution is clear
   The majority of powders which do not require PEG will dissolve rea dily but those that are troublesome, refer to the heating procedure as outlined above.
   In the event that 190 Grain Alcohol (EverClear) is unavailable, you could substitute Bacardi 151.
   List of Materials:
   190 Proof Grain Alcohol or Bacardi 151, PEG 300, PEG 600. Powder, beaker, stir rod, suitable container for holding finished preparation. Weighing scales accurate to 0.001g (if preparing yourself)
   
   You never want to be in a situation where you have to shake it up to use it. While it***8217;s good to shake a solution to ensure even distribution throughout the liquid, you should always prefer to have all of your powder dissolved and not to be able to see any crystals floating around in the liquid
   Ideally you want a solution, not a suspension. If you have a preparation which is little more than powder sitting in liquid, or where after swirling it visibly falls down to the bottom of the vial, it is utterly useless for getting any kind of consistency of dosing. Anything worthy of being called a suspension should be fairly stable after shaking such that you can take your time to draw it.

SARMS are no different really! What is that comment based upon? The fact is while the MAJORITY of AAS are soluble in a 95% ethyl alcohol solution some are NOT such as T-bol, Var and Halo.

SERMS are BEST solubilized in DMSO and NOT ETOH while SARMS, bc of their polar nature, require a combination of DMSO and ETOH.

 

[ebkallday]

Idk isn't there a reason mostly all sarms come in liquid form?

This is because if a research chem company put it in capsules, it would be hard to explain the intended use was no for human consumption. There have been RC companies in the past that put SERMS and SARMS in capsules and have been busted. I don't know if it was directly for that reason but they no longer are around.

 

[Dema]

This is because if a research chem company put it in capsules, it would be hard to explain the intended use was no for human consumption. There have been RC companies in the past that put SERMS and SARMS in capsules and have been busted. I don't know if it was directly for that reason but they no longer are around.

Now that makes since! Thanks for the info guys! My buddy followed the recipe to make nolva up above and gave me some of his supply to try and I'm loving it! Put on some water weight but that dropped after a few days!

Ps. This is the worst tasting sarm/research liquid I've ever tried!

 

[dmore]

why not cap the powder as suggested above?
Just look at Olympus Labs offerings:
http://olympusuk.com/product-category/sarms/
sarms, capped, don't fool around.

 

[Joeblack]

got an easy way

measure out the powder, get some vg vegetable glycerin. Heat it up and mix. BAM done

or get a little 24 capsule maker size 0. use 1g powder and 30g coffee creamer and mix the crap out of it. Then cap. That will make 10mg capsules ( or about )

 

[gui2015jnd]

WHY?

Heck buy a pill press and use it!

Good morning friends, I have 1gr of yk11 (sarms) and also possess some capsules in the hands, I would like to know to make the product in capsular and necessary mix with starch? or can I just get the yk11 powder and put into the capsules? as 5mg for example?

 

[XKawN]

Good morning friends, I have 1gr of yk11 (sarms) and also possess some capsules in the hands, I would like to know to make the product in capsular and necessary mix with starch? or can I just get the yk11 powder and put into the capsules? as 5mg for example?

I posted a thread called "how to cap 101". It is on the second page of the homebrew section. Read that and if you have any questions post there and I'll help.

 

[Dr JIM]

Wrong you have 1 gram of POWDER and until it undergoes formal analytical testing that's all it is, an UNKNOWN POWDER!

Another bathtub brewer, believing what they want or need to believe.