Cyanidin-3-Glucoside as a nutrient partitioner

[Burntoutn3rd]

I went ahead and picked up some of Nootropic Depot's Cyanidin-3-Glucoside (C3G). I already take a large amount of anthocyanin supplements (French Maritime Pine Bark extract, blueberry extract etc) for the range of benefits they offer. Cognitive, energy, motivation, blood sugar, etc.

Going to run it at 250mg C3G/day along with 700mg of 95% Protoanthocyanin French Maritime Pine Bark extract.

The anthocyanin C3G apparently also offers serious nutrient partitioning effects, blocking the uptake of nutrients to fat cells and redirecting to skeletal muscle.

While I can find a TON of anecdote on this from both users and distributors, I haven't come across any study suggesting such.

It also functions as a notably efficacious MAOI, so watching stimulant intake is needed.

If anyone can dig up a relevant study though, I'd be very appreciative!
.

 

[Burntoutn3rd]

Nootropics Depot's blog where the nutrient partitioning effects are mentioned: nootropicsdepot.com/the-colorful-side-of-supplements

 

[AlexDavis43]

I went ahead and picked up some of Nootropic Depot's Cyanidin-3-Glucoside (C3G). I already take a large amount of anthocyanin supplements (French Maritime Pine Bark extract, blueberry extract etc) for the range of benefits they offer. Cognitive, energy, motivation, blood sugar, etc.

Going to run it at 250mg C3G/day along with 700mg of 95% Protoanthocyanin French Maritime Pine Bark extract.

The anthocyanin C3G apparently also offers serious nutrient partitioning effects, blocking the uptake of nutrients to fat cells and redirecting to skeletal muscle.

While I can find a TON of anecdote on this from both users and distributors, I haven't come across any study suggesting such.

It also functions as a notably efficacious MAOI, so watching stimulant intake is needed.

If anyone can dig up a relevant study though, I'd be very appreciative!
.

T-bag magazine has extensive write-ups on their flagship product:



I know some people think polyphenols are bullshit but I'm not one of them.

Just, there's zero evidence of benefits from supplements.

More studies showing no effect, but if you look long enough, can probably cherry pick a few positive findings.

 

[Burntoutn3rd]

Yeah. I read plenty on that one as well. There's just no actual high end human study data on them, lol. Just general anthocyanin studies for the most part

I'm going to use it fasted in the morning. Other polyphenols and flavonoids help the bioavailability a lot apparently, as well as Astragin and Piperine for cyp inhibition and p-glycoprotein inhibition.

250mg c3g
800mg Liposomal Quercetin
50ng Liposomal Fisetin
100mg Astragin
1400mg Circumin
700mg 95%protoanthocyanin French Pine Bark extract (Pycnogenol)
750mg Cacao Flavenols from Cocoavia Memory+
12.5mg Piperine

Stacked with 500ng IM l-carnitine and 100:150mcg Mod grf and Ipamorelin. Hit fasted cardio, then take the rest of my way too many morning time supplements, slam a mobile breakfast and protein shake, then hit my lifting routine.

 

[AlexDavis43]

Yeah. I read plenty on that one as well. There's just no actual high end human study data on them, lol. Just general anthocyanin studies for the most part

I'm going to use it fasted in the morning. Other polyphenols and flavonoids help the bioavailability a lot apparently, as well as Astragin and Piperine for cyp inhibition and p-glycoprotein inhibition.

250mg c3g
800mg Liposomal Quercetin
50ng Liposomal Fisetin
100mg Astragin
1400mg Circumin
700mg 95%protoanthocyanin French Pine Bark extract (Pycnogenol)
750mg Cacao Flavenols from Cocoavia Memory+
12.5mg Piperine

Stacked with 500ng IM l-carnitine and 100:150mcg Mod grf and Ipamorelin. Hit fasted cardio, then take the rest of my way too many morning time supplements, slam a mobile breakfast and protein shake, then hit my lifting routine.

I'd take it all with a big mixed meal. Sounds like you skip breakfast so fasted morning intake is most convenient for you. Kinda minutiae imo.

All those liposomals are designed for better absorption with a mixed meal (or least bad absorption when fasted).

 

[benfrankparkway]

I went ahead and picked up some of Nootropic Depot's Cyanidin-3-Glucoside (C3G). I already take a large amount of anthocyanin supplements (French Maritime Pine Bark extract, blueberry extract etc) for the range of benefits they offer. Cognitive, energy, motivation, blood sugar, etc.

Going to run it at 250mg C3G/day along with 700mg of 95% Protoanthocyanin French Maritime Pine Bark extract.

The anthocyanin C3G apparently also offers serious nutrient partitioning effects, blocking the uptake of nutrients to fat cells and redirecting to skeletal muscle.

While I can find a TON of anecdote on this from both users and distributors, I haven't come across any study suggesting such.

It also functions as a notably efficacious MAOI, so watching stimulant intake is needed.

If anyone can dig up a relevant study though, I'd be very appreciative!
.

glad you are willing to try it out, but with so much other variables (other supplements) how will you know what effects you get from this and not from the other. As is the case with most naturall supplements, it takes a good amount of time to notice difference or at very least to rule out placebo effect.
Keep us posted as I too would have interest in this product as it is more of a novelty and not common.

 

[eery]

you think its superior to 500-1000mg of metforming and/or berberine?

 

[Burntoutn3rd]

glad you are willing to try it out, but with so much other variables (other supplements) how will you know what effects you get from this and not from the other. As is the case with most naturall supplements, it takes a good amount of time to notice difference or at very least to rule out placebo effect.
Keep us posted as I too would have interest in this product as it is more of a novelty and not common.

I already take everything else, it's the only real new addition to my stack. In fact I'm swapping out other Bayberry extracts for it.

 

[benfrankparkway]

I already take everything else, it's the only real new addition to my stack. In fact I'm swapping out other Bayberry extracts for it.

Like "eery" said above would you think its superior than berberine?

 

[Burntoutn3rd]

you think its superior to 500-1000mg of metforming and/or berberine?

Like "eery" said above would you think its superior than berberine?

Different kind of partitioner. I still will take berberine daily, as it shuttles/clears glucose. C3G shuttles fatty acids selectively to muscle cell mitochondria for fuel. It's a PPAR-a agonist. It makes your muscles draw more from fatty acids leading to better lipolysis and slightly enhanced muscle nutrient partitioning.

Then the compound is supposed to have WILD Nootropic effects too. Increases neural blood flow and oxygenation as well as working as a mild MAOI to boost monoamines (Dopamine, serotonin, norepinephrine, etc). Which will also make any other centrally active substance we use much stronger as well. Caffeine, Clen, theobromine, etc, so that's something to watch out for.

I'm about to take it for the first time right now. I'll report back after it kicks in, then again after the gym.

 

[Burntoutn3rd]

I'd take it all with a big mixed meal. Sounds like you skip breakfast so fasted morning intake is most convenient for you. Kinda minutiae imo.

All those liposomals are designed for better absorption with a mixed meal (or least bad absorption when fasted).

I know a couple of the guys at ND very well, they told me the feedback they're getting is taking it with food is very hit or miss, and most people complain about it unless taken in an empty stomach. He said the one exception is taking it down strictly with say like fish oil/flax oil supplements where no fiber holds it up in the stomach where pepsin dismantles it. Fats may help, but you want it to go through your stomach as fast as possible to get out of pepsin's reach

 

[eery]

Different kind of partitioner. I still will take berberine daily, as it shuttles/clears glucose. C3G shuttles fatty acids selectively to muscle cell mitochondria for fuel. It's a PPAR-a agonist. It makes your muscles draw more from fatty acids leading to better lipolysis and slightly enhanced muscle nutrient partitioning.

Then the compound is supposed to have WILD Nootropic effects too. Increases neural blood flow and oxygenation as well as working as a mild MAOI to boost monoamines (Dopamine, serotonin, norepinephrine, etc). Which will also make any other centrally active substance we use much stronger as well. Caffeine, Clen, theobromine, etc, so that's something to watch out for.

I'm about to take it for the first time right now. I'll report back after it kicks in, then again after the gym.

i see, so it acts similarly to cardarine in that regard?

let us know how it works out for you

 

[Burntoutn3rd]

i see, so it acts similarly to cardarine in that regard?

let us know how it works out for you

Very similar. The cool part is it doesn't touch PPAR delta or beta which is what drives tumor growth with Cardarine.

Dosed about 90 minutes ago. Ended up adding 50% on top because I like slightly megadosing new supplements to get a feel for the potential.

So I took 375mg of C3G
1400mg Circumin
100mg Astragin for bioavailability enhancement
Life Extension s Synolytic Activator (Liposomal Quercetin, Apigenin, and Fisetin)
10mg Piperine

It honestly mentally feels like a light amount of Ritalin or Adderall. I'd easily put it on par with 20mg Adderall in stimulation and drive. My heart rate is noticably raised, I feel my pulse in my chest and head at the moment.

Followed it with Greek yogurt, protein granola, raspberries, and bcaa's+Electrolytes.

No caffeine or anything yet, and honestly I'm probably not going to slap that on top with the energy level already present.

Lastly my field of vision is greatly opened up. I used to get that effect with stuff like phenylpiracetam before getting a tolerance to cholinergic nootropics. It's definitely attributable to Increased neural blood flow.

In hindsight I'm really glad I didn't throw the cacao Flavenols on top. Those alone are already pretty potent stimulants/entactogens in the doses provided in Cocoavia.

 

[benfrankparkway]

Very similar. The cool part is it doesn't touch PPAR delta or beta which is what drives tumor growth with Cardarine.

Dosed about 90 minutes ago. Ended up adding 50% on top because I like slightly megadosing new supplements to get a feel for the potential.

So I took 375mg of C3G
1400mg Circumin
100mg Astragin for bioavailability enhancement
Life Extension s Synolytic Activator (Liposomal Quercetin, Apigenin, and Fisetin)
10mg Piperine

It honestly mentally feels like a light amount of Ritalin or Adderall. I'd easily put it on par with 20mg Adderall in stimulation and drive. My heart rate is noticably raised, I feel my pulse in my chest and head at the moment.

Followed it with Greek yogurt, protein granola, raspberries, and bcaa's+Electrolytes.

No caffeine or anything yet, and honestly I'm probably not going to slap that on top with the energy level already present.

Lastly my field of vision is greatly opened up. I used to get that effect with stuff like phenylpiracetam before getting a tolerance to cholinergic nootropics. It's definitely attributable to Increased neural blood flow.

In hindsight I'm really glad I didn't throw the cacao Flavenols on top. Those alone are already pretty potent stimulants/entactogens in the doses provided in Cocoavia.

So walk me through dosing time. You are taking it on empty stomach preworkout. As in fiber holds it up. Maybe best protocol would be empty stomach 1st thing in morning prior to cardio?

 

[Avies48]

Id die… thats a lot of stuff to take erry morning plus what ever else u take…

But my body is different and stimulant type effects fuck me up…

 

[Burntoutn3rd]

Id die… thats a lot of stuff to take erry morning plus what ever else u take…

But my body is different and stimulant type effects fuck me up…

I was going to post my full stack last month, but I knew I was about to change up a solid 40% of it at the end of June (I make about an 800 dollar order every 60 days) from a host of cancer preventatives and side effects mitigators back into straight enhancement again. Obliviously kept some of the stuff I added in for cancer like high dose Sulfloraphane from Jarrow's.

Now that I got everything in to change it up I was going to type the full list out finally.
.it a lot, and it's honestly annoying because it's enough to cause noticable nausea a couple times a day) I'm taking like 12 pills AM fasted, 30 pills breakfast, 25 more at noon. 20 at 5 and another 10 at bed. Plus bulk powders and stuff I mix into shakes/pres/nightcaps or just dump sublingually.


At the same time, my lab values are immaculate and I feel on top of the world on a day to day basis physically and cognitively.

Quite a few of the things I take are just general anti-aging so there no objective feel to them, just a lot of data showing enhanced autophagy and increased lifespan (NMN, Fisetin, Spermadine, etc)

Then peptides and such.


Stimulants do really hit me hard and I have to be careful with them. Yesterday that was purely pleasant though, perfect level of stimulation and edge.

I'm not sore in the slightest today after hitting heavy weight legs last night. That wouldn't have happened a week ago which I can give an acute success example of.

 

[AlexDavis43]

I'm taking like 12 pills AM fasted, 30 pills breakfast, 25 more at noon. 20 at 5 and another 10 at bed.

Jesus.

 

[Burntoutn3rd]

Jesus.

In fairness it's a lot of single ingredient minerals, vitamins, cofactors etc. A majority are legitimate supplements, only a few really get into the realm of playing with polypharmacy.

 

[Avies48]

In fairness it's a lot of single ingredient minerals, vitamins, cofactors etc. A majority are legitimate supplements, only a few really get into the realm of playing with polypharmacy.

Just list em!! Along with what they do!! Im sure @NotHuman would love to see ur list and drop some knowledge!

 

[AlexDavis43]

In fairness it's a lot of single ingredient minerals, vitamins, cofactors etc. A majority are legitimate supplements, only a few really get into the realm of playing with polypharmacy.

Just list em!! Along with what they do!! Im sure @NotHuman would love to see ur list and drop some knowledge!

That's a pretty big ask! I wouldn't expect anyone to do that for free.

Hey @Burntoutn3rd this could be a side hustle for you. Start a patreon and write a few paragraphs per compound every week. You have like 2 years of content already.