DNP and Metformin

[Empire Boy]

I recently finished PCT, and I have currently finished a 4 week cycle if insulin w/ a GHRH/GHRP combo (that I am continuing) PWO, followed 30mins later by 8ui of insulin. This of course is based off Dat's protocol. I also used 100mcg of T4 to compensate for any thyroid depression.

I only ran the 'slin (humalog) PWO, and I used a liquid diet of 200grams of whey, while adjusting my dextrose (high GI) and oats (low GI) according to BG measurements for the first 3 hours with 100 grams of animal protein at the 3 hours mark w/ additional high GI carbs if needed. I was able to drop a % of bf while maintaining my weight that I gained while on a cycle of AAS.

Now that I am finished with the 'slin, I am regaining sensitivity by running 2000mg ed of metformin. I have also got my hands on DNP. My plan is to run a low dose of the DNP 200mg ed for 10 days alongside the metformin. I do not plan on running a keto diet of any sorts, rather just maintain my a maintenance diet with a good balance of macros. I will also continue to use 100mcg of T4 (again, for any depression of thyroid). I know and understand what DNP is, I know the risks, I understand the biochemistry of the drug, and it is not as dangerous as it is often made out to be. In fact a friend actually had his 85 year old grandmother do a cycle of DNP @ 200mg ed for 3 weeks...she enjoyed the weight loss! He himself ran it at 1500mg ed...and besides the extreme discomfort, did not 'fry himself'.

But, I'm curious if anybody has ran metformin with DNP and what the results might have been? I was planning on using it with my 'slin cycle, but things changed...

 

[whitegato777]

metformin isnt worth the side, hgh plus dnp and hgh would be better. tren would help to keep cortisol down

 

[Ragin8]

1500mg of DNP... goodness.

On a separate note, I'm inclined to agree with this guy about DNP and hgh. Can't really comment on metformin

metformin isnt worth the side, hgh plus dnp and hgh would be better. tren would help to keep cortisol down

 

[Empire Boy]

I'm running a GHRH/GHRP combo x3 daily with niacin, clonidine, melatonin and huperzine a to intensify the pulse, so I am getting an endogenous amount of GH equal to about 4-6ui of synthetic HGH, and your own GH is far superior!

So far on 2000mg of metformin w/ 200mg DNP ed there are no sides, and am day 3 (DNP 'builds' so fully expect sides soon, and can tell the mitochondria are working harder as I feel a bit more 'tired' just sitting. I also had a big carb meal tonight (am in UK) and 30mins later BG was 6.4 (in UK, 5.6 is considered a fasted state)...so thats pretty good! The only thing that concerns me is that metformin blocks the release of IGF-1 from the liver...

 

[Ragin8]

As far as the DNP goes, it took me about 3 days at 200mg before I noticed the sides (mostly night sweats and easy fatigue). Planning on running it again in another week or so when I have the time I need to dedicate to training and have a proper diet

Guess i need to do some more research on GHRH and GHRP; Sounds interesting though. Keep us updated on your results.

 

[whitegato777]

side from liver damage from metformin what be noticable right away and most guys ive known to use it say there is no benifit. are u using cjc 1295?

 

[Empire Boy]

side from liver damage from metformin what be noticable right away and most guys ive known to use it say there is no benifit. are u using cjc 1295?

Using Mod Grf 1-29 w. GHRP-2 each at saturation x3 daily.

I agree on metformin, am using to regain sensitivity after a 'slin cycle based on Dat's protocol, But I agree. The long term effects look bleak, even though metformin is voraciously advocated by the anti-ageing set!

 

[Empire Boy]

As far as the DNP goes, it took me about 3 days at 200mg before I noticed the sides (mostly night sweats and easy fatigue). Planning on running it again in another week or so when I have the time I need to dedicate to training and have a proper diet

Guess i need to do some more research on GHRH and GHRP; Sounds interesting though. Keep us updated on your results.

I really like the GHRH/GHRP combo, I feel a lot better physically, the GH release has made me leaner, and I feel more rested. I plan on running the peptides for 6 months on a x5 a week, x3 a day protocol. Resting the pituitary is probably a good idea, hence the 2 days off, and these are simply my non-WO days.

Its good to hear this on the DNP. Its my first run with DNP, and as I have a background in biochemistry, I was quite worried about the whole prospect of ingesting such a powerful oxidative uncoupler (although aspirin is a mild uncoupler as well, most forget that it is for this reason it is included in ECA stacks....if DNP were legal we would have ECD stacks, lol)...But it is tempting to up the dose of DNP as it takes time....I think this is where those new to DNP fall in to a trap...they don't 'feel' it after a few days so take more, than day 4-5, they are miserable!

But I do really enjoy these peptides...

 

[whitegato777]

I really like the GHRH/GHRP combo, I feel a lot better physically, the GH release has made me leaner, and I feel more rested. I plan on running the peptides for 6 months on a x5 a week, x3 a day protocol. Resting the pituitary is probably a good idea, hence the 2 days off, and these are simply my non-WO days.

Its good to hear this on the DNP. Its my first run with DNP, and as I have a background in biochemistry, I was quite worried about the whole prospect of ingesting such a powerful oxidative uncoupler (although aspirin is a mild uncoupler as well, most forget that it is for this reason it is included in ECA stacks....if DNP were legal we would have ECD stacks, lol)...But it is tempting to up the dose of DNP as it takes time....I think this is where those new to DNP fall in to a trap...they don't 'feel' it after a few days so take more, than day 4-5, they are miserable!

But I do really enjoy these peptides...

so you think ECA stack with dnp would be a good combination?

 

[Empire Boy]

so you think ECA stack with dnp would be a good combination?

Lots of people use ECA while on DNP for the boost...I prefer caffeine. The effects of aspirin as an oxidative uncoupler compared to DNP is like comparing Curious George to King Kong...

 

[GeorgeWBush]

metformin has been proven to only be effective in those with diabetes or with insulin resistance and insulin usage in and of it self will not produce insulin resistance or diabetes.

metformin is a nasty drug, i wouldn't mess with it for a lot more reasons than because of it being unnecessary and redundant and i'd especially not touch that shit alongside dnp. that is a dangerous combination in which i can very well imagine serious problems arising

 

[Ragin8]

I really like the GHRH/GHRP combo, I feel a lot better physically, the GH release has made me leaner, and I feel more rested. I plan on running the peptides for 6 months on a x5 a week, x3 a day protocol. Resting the pituitary is probably a good idea, hence the 2 days off, and these are simply my non-WO days.

I have heard of a few people running this protocol and a guy on another forum gave me a link to read up. At least anecdotally, it sounds promising.

so you think ECA stack with dnp would be a good combination?

Lots of people use ECA while on DNP for the boost...I prefer caffeine. The effects of aspirin as an oxidative uncoupler compared to DNP is like comparing Curious George to King Kong...

LOL, well said.

 

[nunya.bizness]

I believe Lyle and some other big diet names looked into Metformin some time ago, and the verdict was that it wasn't useful. It had a very brief appearance on a few of the forums as well. I considered it myself when I determined that I couldn't take DNP due to quick onset of histaminic symptoms while even taking a low dose. Very disappointing since I like to eat and hate cardio.

 

[JSB]

I really like the GHRH/GHRP combo, I feel a lot better physically, the GH release has made me leaner, and I feel more rested. I plan on running the peptides for 6 months on a x5 a week, x3 a day protocol. Resting the pituitary is probably a good idea, hence the 2 days off, and these are simply my non-WO days.

Its good to hear this on the DNP. Its my first run with DNP, and as I have a background in biochemistry, I was quite worried about the whole prospect of ingesting such a powerful oxidative uncoupler (although aspirin is a mild uncoupler as well, most forget that it is for this reason it is included in ECA stacks....if DNP were legal we would have ECD stacks, lol)...But it is tempting to up the dose of DNP as it takes time....I think this is where those new to DNP fall in to a trap...they don't 'feel' it after a few days so take more, than day 4-5, they are miserable!

But I do really enjoy these peptides...

do you prefer it to mod1-29/ghrp

 

[PillarofBalance]

so you think ECA stack with dnp would be a good combination?

Ephedrine and DNP is a fantastic stack... Ephedrine frees up the fatty acids faster allowing more to be burned at a staggering rate by the DNP.. Plus the energy helps.

 

[PillarofBalance]

metformin has been proven to only be effective in those with diabetes or with insulin resistance and insulin usage in and of it self will not produce insulin resistance or diabetes.

metformin is a nasty drug, i wouldn't mess with it for a lot more reasons than because of it being unnecessary and redundant and i'd especially not touch that shit alongside dnp. that is a dangerous combination in which i can very well imagine serious problems arising

Like what...

 

[benchingover500]

I would avoid met because the last thing you want is to throw off you insulin cycle. When your insulin cycle is thrown off, your body either secretes insulin too early or too late & you began to see metabolic syndrome, diabetes, irreversible renal damage, cardiovascular disease, & PVD.