Factors that decrease AAS effectiveness?

[jakethepig67]

I’m a little curious if there is any environmental or biological factors that could affect AAS absorption/effectiveness. If so what are some lifestyle choices you can make to get the most out of your AAS usage.

 

[eery]

getting enough quality sleep, eating enough micro, macronutrients and antioxidants, lower stress/cortisol/oxidative stress, good cardiovascular health, thats what pops up first in my mind. Basically being healthy and having an effective working body.

Outside of that theres theoretical things like carnitine that is said to upregulate androgen receptor density.

 

[jakethepig67]

That’s what I was already kind of thinking. Being in good metabolic health seems like a no brainer. Im curious if there are any hormones that might inhibit absorption.

 

[Palifter]

Things that negatively effect AAS effectiveness are typically well within one’s control - diet and exercise. Most fall short here.

Don’t overthink this. Cover the basics and you’ll be better off than 90%.

 

[lukiss96]

Things that negatively effect AAS effectiveness are typically well within one’s control - diet and exercise. Most fall short here.

Don’t overthink this. Cover the basics and you’ll be better off than 90%.

I wanted to say this. But you did first just better.

 

[DinoBB76]

quality sleep , training and eat less protein ; take a break , fix your sleep eat more protein and less carb and restart

 

[TribulusMax]

Alcohol is bad for gains even worse with AAS

 

[Ghoul]

Pot usage has far more of an impact on hormones than many realize, though it's very well documented.

 

[eery]

Pot usage has far more of an impact on hormones than many realize, though it's very well documented.

any good resources on this? does this go for all cannabis strains and CBD as well?

 

[Ghoul]

any good resources on this? does this go for all cannabis strains and CBD as well?

The endocannabinoid system interacts with the HPG axis significantly.

Minireview: Endocannabinoids and Gonadal Hormones: Bidirectional Interactions in Physiology and Behavior

Endocannabinoids act as a major neuromodulatory system in a variety of physiological and behavioral functions. Three major lines of evidence suggest that t

academic.oup.com

 

[emogothtiddy]

Low e2 is the worst for me.

 

[TribulusMax]

Low e2 is the worst for me.

What do you consider low E numbers wise?

 

[bigboy420]

HPG axis

EHh thoes were natty rats. Beliveee

 

[Deleted member 59947]

I’m a little curious if there is any environmental or biological factors that could affect AAS absorption/effectiveness. If so what are some lifestyle choices you can make to get the most out of your AAS usage.

Blocking aromatase. E2 is essential to androgen receptors activation.

Melatonin also downregulates androgen receptors.

Being surrounded by plastic EDC that occupy both androgen and estrogen receptors.

That's it. All other bro advice about cardio and sleep are missing your point about making hormones effective, you weren't asking about general health advice.

As one of the older vets of this forum, I apologize about the comprehension skills of the newer members.

 

[eery]

Blocking aromatase. E2 is essential to androgen receptors activation.

Melatonin also downregulates androgen receptors.

Being surrounded by plastic EDC that occupy both androgen and estrogen receptors.

That's it. All other bro advice about cardio and sleep are missing your point about making hormones effective, you weren't asking about general health advice.

As one of the older vets of this forum, I apologize about the comprehension skills of the newer members.

Do you have more information on melatonin down regulating androgen receptors? That's not something I've heard before