MESO-Rx
Anabolic Steroids
GLPs and hiccups
- Thread starter Bigoldguy
- Start date
I and @BamaCrazy posted our personal stories about intolerable Reta hiccups in here. Where were you in the dosing titration?
Yep, had moved up from 0.25 to 0.5...afraid to even do it back at 0.25. I guess I missed the post by you two...my bad.
I'm probably going to try retatrutide again, but moving up in dosage more slowly, and with a lower dose ceiling. It could be that you just moved up in sema dose too far for your body to adjust. Standard schedule is to increase by 0.25 every 4 weeks, right?
Yeah, youre probably right...it was pretty damn miserable though.
I hear you, brother in hiccuping. Weirdly, the only time I wasn't hiccuping was asleep or when working out. So I never missed a day during that period
As weird as it sounds, sex stopped them for a couple hours at a time. Thanks goodness the fiance was a trooper! 8)I hear you, brother in hiccuping. Weirdly, the only time I wasn't hiccuping was asleep or when working out. So I never missed a day during that period
BamaCrazy
Banned
Almost two months after my hiccups stopped I tried some compound Tirz I had sitting unused in the fridge. 5mg week 1, 5mg week 2. 2 days after that 2nd injection I started having hiccups again. Not as frequent or as violent. Lasted 2 days. I waited a week and tried 2mg Reta. 2mg weeks one and two. 3mg week 3. I’ll be injecting 3mg again today. So far no issues. My goal is to get to 4mg and stay at that dose for a while.
I’m right behind you. My wife is nervous about my self-prescribed Chinese goods so she talked me into trying tirz for a couple of weeks, but I’m already feeling the same fatigue I got before.
Reta was so beneficial beyond weight management, I think it’s worth the risk of another hiccup episode. Depending on what phase I’m in, I may vary the dose, but I want to stay on Reta at least 9 months out of the year. I’m going to titrate up very slowly to see if I can get less of the HR increase and allodynia than last time. If not, there’s always ivabradine.
Try all the tricks. If they dont go, look into Reglan or Thorazine. Took thorazine to clear mine.I spoke to soon…fucking hiccups for 4 hours and counting
This is a real motherfucker of a problem. It's a common side effect, and the usual tricks -- breathing exercises or Valsalva, chewing gum, drinking water -- often don't work. To my knowledge, there isn't any published work on this, so clinicians are working a bit blind.
Anecdotally, some people have found baclofen (trade names Gablofen and Lioresal) to be effective. Starting dose is typically 5 mg 3x/day. If you get no relief you can titrate up to 25 mg 3x/day, but don't be an asshole with the increment. If it works, you can stay on it long-term. The most likely side effect is CNS depression, but it's typically not severe at starting doses.
Caveat - do not abruptly quit baclofen. Taper down by small increments every 5-7 days. If you are at a high dose and quit abruptly, the withdrawal can be life threatening.
There are two other medications that are sometimes used for medically induced or otherwise intractable hiccupping, but they have a higher risk profile, tend to speed up gastric emptying, and can only be used for a couple months in one case or a few days in another. If baclofen doesn't work, there probably isn't a medical solution.
Anecdotally, some people have found baclofen (trade names Gablofen and Lioresal) to be effective. Starting dose is typically 5 mg 3x/day. If you get no relief you can titrate up to 25 mg 3x/day, but don't be an asshole with the increment. If it works, you can stay on it long-term. The most likely side effect is CNS depression, but it's typically not severe at starting doses.
Caveat - do not abruptly quit baclofen. Taper down by small increments every 5-7 days. If you are at a high dose and quit abruptly, the withdrawal can be life threatening.
There are two other medications that are sometimes used for medically induced or otherwise intractable hiccupping, but they have a higher risk profile, tend to speed up gastric emptying, and can only be used for a couple months in one case or a few days in another. If baclofen doesn't work, there probably isn't a medical solution.
BamaCrazy
Banned
I had hiccups for 22 days straight this year from Reta. The doctors gave me Baclofen, Gabapentin, Chlorpromazine, Omeprazole, Pantoprazole and Metoclopramide. None of them stopped the hiccups. Baclofen paired with Gabapentin allowed me to fall asleep with hiccups, but I’d still occasionally wake up with hiccups.
One drug I wasn’t prescribed but have since purchased to have on hand is haloperidol. I’ve heard that works well for some.
BamaCrazy
Banned
A complete nightmare. The vagus nerve controls critical things like breathing, digestion and BP and that nerve was completely freaking out. The only good thing that came out of it was I got MRIs, Ultrasounds, CT scans, endoscopy, Echocardiogram and EKG of everything from my brain to my bunghole. They never found anything other than blaming Reta. But they also didn’t find anything wrong with my brain, heart, lungs, liver, kidney, etc.
BigDadd7
Member
Finger in your butt
pubmed.ncbi.nlm.nih.gov
Termination of intractable hiccups with digital rectal massage - PubMed
A 60-year-old man with acute pancreatitis developed persistent hiccups after insertion of a nasogastric tube. Removal of the latter did not terminate the hiccups which had also been treated with different drugs, and several manoeuvres were attempted, but with no success. Digital rectal massage...
pubmed.ncbi.nlm.nih.gov
BamaCrazy
Banned
Had I only known.Finger in your butt
Termination of intractable hiccups with digital rectal massage - PubMed
A 60-year-old man with acute pancreatitis developed persistent hiccups after insertion of a nasogastric tube. Removal of the latter did not terminate the hiccups which had also been treated with different drugs, and several manoeuvres were attempted, but with no success. Digital rectal massage...
