Interesting. I have had itching or arms and legs recently of unknown origin. After trying to evaluate what I have done different in the last few months since it started, I was still clueless. Im not a cosmetic type user but I had to start using lotions with minimal help but tanning seem to take care of most of it. After your question it finally came to me. I take 500-750 week of hcg with trt and continue it on blasts. I decided to change my source of hcg to go along with my prescription meds for convenience sake. I have only taken pregnyl and chormion brands in the past. I recently switched to Fertigyn and Sifasi like I said for convenience sake. Im not certain but I m pretty sure the itching started about the time I switched brands. I don't know if its an additive/filler or even if it truly is the hcg causing it. I will be re stocking soon on necessities and will only order chormion ( I hear pregnyl is discontinued???) from here on out and see if it makes a difference. Will follow up to let you know. What brand are you using?