How long does DNP effects last?

nervje

Member
Im wondering how long do ALL of the dnps effects last after the last dose?
Lets say on a dosage of 500mg a day, how long would it take for the system to work the same as before the DNP, meaning not only the sweats to stop, but also the glycogen and water in the muscle to fill back up, muscle recovery going back up, insulin production and all that being normal again (as Ive read a few posts 'proving' DNP stops muscle growth due to insulin inhibition etc), also how long would it take for thyroid to function normal again as DNP lowers that too (hence why one should supplement t3 during dnp), or is it literally the day u stop the sweats, your system is 'recovered'?
Before anyone bullshits, im just trying to learn about this drug
 
Just anecdotally from LOTS of self experimentation with dnp , the heat and lethargy usually completely dissappears within 48hrs.

Then within 3-4 days you start getting good pumps in the gym again. I personally hold a shit load of water on dnp , and it takes about 10 days to drop the water for me.

As far as your thyroid function i dont really have a solid answer for that , but you definitely dont need to supplement t3 while on dnp . Ive run it both ways and its makes zero difference in fat loss or energy levels . The action of the dnp is so strong that the suppressed thyroid is just a drop in the bucket so to speak when it comes to fat loss.

As far as insulin , i also dont have a definitive answer but id imagine it be once your atp production comes back to normal. Basically, how i understand , atp cant be elevated intracellularly (including pencreatic beta cells ) so the feedback system through the katp channels is basically turned off making you diabetic in essence while your on dnp . So im assuming once the dnp clears your system(or enough so that atp production becomes more efficient ) insulin production would return to normal.

Sorry thats mostly my own anecdotal experience with dnp , but hopefully that gives you an idea and place to start some further research..
 
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Just anecdotally from LOTS of self experimentation with dnp , the heat and lethargy usually completely dissappears within 48hrs.

Then within 3-4 days you start getting good pumps in the gym again. I personally hold a shit load of water on dnp , and it takes about 10 days to drop the water for me.

As far as your thyroid function i dont really have a solid answer for that , but you definitely dont need to supplement t3 while on dnp . Ive run it both ways and its makes zero difference in fat loss or energy levels . The action of the dnp is so strong that the suppressed thyroid is just a drop in the bucket so to speak when it comes to fat loss.

As far as insulin , i also dont have a definitive answer but id imagine it be once your atp production comes back to normal. Basically, how i understand , atp cant be elevated intracellularly (including pencreatic beta cells ) so the feedback system through the katp channels is basically turned off making you diabetic in essence while your on dnp . So im assuming once the dnp clears your system(or enough so that atp production becomes more efficient ) insulin production would return to normal.

Sorry thats mostly my own anecdotal experience with dnp , but hopefully that gives you an idea and place to start some further research..

Your answer was on point though and without any studies, it would make a lot of sense what you just said
 
Lets say on a dosage of 500mg a day, how long would it take for the system to work the same as before the DNP...

I am still on my first DNP cycle so I can't answer from personal experience. For what it's worth, the math says at at 500mg taken once each day the concentration peaks at 1,348mg. Seven days after you stop, it's down to 53mg. It would take 16 days for the concentration to drop to below 1mg.
 
I am still on my first DNP cycle so I can't answer from personal experience. For what it's worth, the math says at at 500mg taken once each day the concentration peaks at 1,348mg. Seven days after you stop, it's down to 53mg. It would take 16 days for the concentration to drop to below 1mg.
Whats the formula u had for that equation?
 
Whats the formula u had for that equation?

New Concentration = dose + (last total concentration * (0.5 ^ (Dosage Period / half life )))

Where:

- Dosage Period is in hours (24 if you take it once a day, 12 if you take it twice a day)
- Half life = 36 (it may not but that seems to be the consensus)

I have two spreadsheets, one for once daily and another for twice daily.

It's important to note that this only works if you take it at regular intervals. That is, something like once a day every day at 7:00PM. Or twice a day, always at 7:00AM and then at 7:00PM.

I log everything very carefully, including my body temp once a day. I have found that when the predicted concentration is at about 1,300mg or so is when I don't feel well. I'll get headache and be very tired, and sweat more. Tylenol helps with the headaches. Of course this is just for me, your mileage may vary.
 
New Concentration = dose + (last total concentration * (0.5 ^ (Dosage Period / half life )))

Where:

- Dosage Period is in hours (24 if you take it once a day, 12 if you take it twice a day)
- Half life = 36 (it may not but that seems to be the consensus)

I have two spreadsheets, one for once daily and another for twice daily.

It's important to note that this only works if you take it at regular intervals. That is, something like once a day every day at 7:00PM. Or twice a day, always at 7:00AM and then at 7:00PM.

I log everything very carefully, including my body temp once a day. I have found that when the predicted concentration is at about 1,300mg or so is when I don't feel well. I'll get headache and be very tired, and sweat more. Tylenol helps with the headaches. Of course this is just for me, your mileage may vary.
The only problem is that the half life doesnt really translate to much in terms of side effects with dnp . Not to say it isnt useful to know and understand . But At 4 days your under 200mgs concentration (at a 500mg daily dose ) , at which point basically all noticable sides other than maybe some water retention are gone . And i havent seen any studies to prove its even suppresive to the thyroid , other then a few conflicting studies in rats.

Plus side effects seem to swing pretty widely from person to person with dnp . So honestly the best course is to start at minimal doses with the drug and learn exactly how you personally react to it .
 
The only problem is that the half life doesnt really translate to much in terms of side effects with dnp . Not to say it isnt useful to know and understand . But At 4 days your under 200mgs concentration (at a 500mg daily dose ) , at which point basically all noticable sides other than maybe some water retention are gone . And i havent seen any studies to prove its even suppresive to the thyroid , other then a few conflicting studies in rats.

Plus side effects seem to swing pretty widely from person to person with dnp . So honestly the best course is to start at minimal doses with the drug and learn exactly how you personally react to it .
I 100% agree with everything @LordSamuilo has stated so far in this thread. It mimics my personal experience with DNP as well. Several factors really are user dependent and require you actually using it to see how you react.

The water retention is that last thing to clear. I'm typically side effect free (except for the water retention) with 2-4 days depending on the dosage I was running. Pretty much exactly as already stated. I've never experienced and noticeable thyroid suppression and my insulin sensitivity is restored pretty much as soon as the sides subside. The first thing I notice is better pumps and I fill back out.

DNP is a make a plan, take it according to that plan, do the work and don't over think it drug. Pretty much just try to put it out of your head that you're on it. When it's done and the water comes off you get to see what happened and by then you're already pushing forward with the rest of your plan. I only use it to kick off prep typically so it's just one of the many tools in the prep tool box.
 
I don't disagree with any of that, I was just pointing out how long it takes to clear completely, and providing the formula that was requested. I did say I'm new to this.

Being near the end of a 3 week DNP cycle, though, I have noticed something odd. The scale has gone down but the measurements have not changed much. I can't think of a good reason for that, other than perhaps as the fat goes, the water stays and its bloating. Does that make sense?
 
I can't think of a good reason for that, other than perhaps as the fat goes, the water stays and its bloating. Does that make sense?
Yeah its pretty typical , once your off 10 days or so your body will flush that water and you'll see a huge difference . I hate it because it screws with your mind , ill lose scale weight the first few dayz then it stalls and i just start looking watery and flat . But just be patient after you come off and youll start drying out , water really is the last thing to go!


. I only use it to kick off prep typically so it's just one of the many tools in the prep tool box.
Yeah i completely agree that is where dnp really shines . I tried using it late in my last prep and it made life 100x harder. The bloat , lethargy , and revenous hunger i got was terrible, and completely counter productive. But its a god send for getting you down under 10% ! Dnp is like an abusive spouse , it beats me mercilessly but i always end up going back for more:D
 
Yeah its pretty typical , once your off 10 days or so your body will flush that water and you'll see a huge difference . I hate it because it screws with your mind , ill lose scale weight the first few dayz then it stalls and i start looking watery and flat . But just be patient after you come off and youll start drying out , water really is the last thing to go!



Yeah i completely agree that is where dnp really shines . I tried using it late in my last prep and it made life 100x harder. The bloat , lethargy , and revenous hunger i got was terrible, and cometely counter productive. But its a god send for getting you down under 10% ! Dnp is like an abusive spouse , it beats me mercilessly but i always end up going back for more:D


The term every competitor hates to hear or say. Flat and looking fat. That's DNP in a nut shell with regards to the look it produces while you're on it.


No way I'd use it at the end or even middle of prep. I'd be a wreck and looking to jump off a bridge thinking I've lost all my gainzzzz. LOL.
 
'd use it at the end or even middle of prep. I'd be a wreck and looking to jump off a bridge thinking I've lost all my gainzzzz. LOL.

Haha sounds exactly how i felt , it was a lesson learned the hard way for sure.

From here on out inside 8 weeks for me its only cardio, diet , and as much as hate crap probably a little clen as far as cutting drugs goes .
 
How long do you guys generally run DNP for? Let’s say you take 500 mg starting day 1.

This is not from personal experience, from what I have read looks like a lot of guys do 20 days. Some prefer a high dose for 7 or so days, others a low dose for 30 days. Based on research, I chose to do 3 days at 200mg, then work my way up to 500mg per day, taken once in the evening. Upon reflection, I probably should have just jumped from 200mg per day to 500mg per day, but I'm ultra paranoid and wanted to proceed carefully, especially since it was my first time.

I may extend it 3 days to make up for those first 3 days testing it out at 200mg.

But, from what I have researched, starting out right at 500mg is not a great idea unless (1) you know how you respond to it (regarding allergies and such) and (2) you have some on hand you used before and are confident it's legit and not overdosed. Bear in mind that even if your new stuff came from a source you have used in the past, the dosage and mixture (if any) could still be different than you had previously.
 
Yeah its pretty typical , once your off 10 days or so your body will flush that water and you'll see a huge difference . I hate it because it screws with your mind , ill lose scale weight the first few dayz then it stalls and i just start looking watery and flat . But just be patient after you come off and youll start drying out , water really is the last thing to go!

Thanks very much, I'll keep that in mind.
 
This is not from personal experience, from what I have read looks like a lot of guys do 20 days. Some prefer a high dose for 7 or so days, others a low dose for 30 days. Based on research, I chose to do 3 days at 200mg, then work my way up to 500mg per day, taken once in the evening. Upon reflection, I probably should have just jumped from 200mg per day to 500mg per day, but I'm ultra paranoid and wanted to proceed carefully, especially since it was my first time.

I may extend it 3 days to make up for those first 3 days testing it out at 200mg.

But, from what I have researched, starting out right at 500mg is not a great idea unless (1) you know how you respond to it (regarding allergies and such) and (2) you have some on hand you used before and are confident it's legit and not overdosed. Bear in mind that even if your new stuff came from a source you have used in the past, the dosage and mixture (if any) could still be different than you had previously.
Last time I ran it I did what you did. 250 mg first 3-5 days. 500 mg for 22 days. Total of 25 days. This time, I started at 500 mg from day 1 as 250 mg doesn’t do anything for me. 500 mg is pretty tolerable too but I’m not going to increase it. The plan is 25 days at 500 mg. The only thing that gets to me is the lethargy... it’s day 1 and I already feel tired lmao.. maybe it’s my mind fcking with me, but whatever. I think the results, if done SAFELY, are out of this world.
 
I think the results, if done SAFELY, are out of this world.

Last night, a few hours after I took it, I went for a 40 minute treadmill run, sweat like crazy, pushed way too hard but survived. This morning, the scale was down 1.6 pounds. So maybe I sweat out a lot of the water, but also, since it boost your metabolism, maybe the run kicked it into high gear.
 
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