How long until you feel sides from DNP?

[dfein]

Took 100mg then another 100mg 6 hours later. This is my first day. I don't really feel anything, but I think it might be increasing my heart rate.

 

[ericraven2003]

It can take a few days sometimes. Don't up the dose. Just be patient. I never go over 200 mg a day ,and it usually takes 2-3 days to see some sides. Example for me would be sweating at night.

 

[Conciliator]

but I think it might be increasing my heart rate.

Probably not. In 1945, Rosenblum looked at this specifically in his paper "Rate of Bloodflow in Patients Receiving Dinitrophenol." (1935, JAMA 104:1592). He concluded that in those on DNP, there's no significant change in the pulse rate.

Cutting and Tainter, in their watershed paper on DNP, "Use of Dinitrophenol in in Obesity and Related Conditions" (1933, JAMA 101:1472) reported that "In patients with normal blood pressure no important change in either systolic or diastolic pressure or in pulse rate has been demonstrated."

In a paper in 1934 entitled "Clinical Circulatory Effects of Dinitrophenol" (JAMA 103:912), Stockton and Cutting reported that hypertensive patients showed a definite fall of both systolic and diastolic pressures whereas hypotensive patients showed little or no further decrease of blood pressure.

Also, let me quote Simkins, who oversaw 181 subjects in the most extensive long term DNP trial to date, lasting from 4 months to over a year of DNP administration.

CARDIOVASCULAR SYSTEM

Dinitrophenol is remarkable for its lack of significant effects on the cardiovascular system even when the basal metabolic rate is raised to high levels... In the present series only one (who became toxic) developed tachycardia [of 159]. Otherwise the patients showed no significant change in pulse rate.

Many investigators in small series of cases, found no change in blood pressure. [8 references]. Others found a marked difference in the response of hypertensive and nonhypertensive patients...

In the present series (181 patients) were twelve hypertensive patients (ten female and two male), of whom ten were placed on dinitrophenol medication. Seven were so called essential hypertensives, two had chronic nephritis with hypertension dating from nephritic toxemias of pregnancy, and one had a malignant hypertension. In all ten, striking amelioration of the hypertension occured rapidly. The blood pressure dropped sharply within one to five weeks. One of the nephritic patients saw a drop from 200/156 to 120/80 in three weeks and to 144/88 at the end of two more weeks. Prior to this for eighteen months she had had a hypertension ranging from 180/110 to 230/156, accompanied by severe headaches, dyspenea and dizziness, and irreduccible by almost every drug and method in current use for hypertension. She now became asymptomatic for the first time in eighteen months. The blood pressure level stayed down for a few weeks after the dinitrphenol was stopped and then rose again, with a return of the original symptoms...

Typical of the response of the essential hypertension is one of the patients, a man of 39, who had been a hypertensive since the age of 19 and who had a familial history of hypertension. At the end of two weeks' treatment his blood pressure fell from 166/110 to 148/90 and in one more week to 116/82. In most of the patients the blood pressure rose gradually after the dinitrophenol was stopped, unless there were large, permanent losses of weight.

Bradycardia is an extremely unusual occurance. It was found in only two patients. No similar cases are reported in the literature. In one patient it was associated with latent icterus. The pulse rate dropped steadily from 88 to 56 at the end of four weeks' medication. During the third week the icteric index was 20 and the direct van den Bergh test showed a delayed, weakly positive reaction. The dinitrophenol was not discontinued and the pulse rate gradually rose to normal within a week and remained normal thereafter...

 

[dfein]

Well, I'm not sure if the DNP I have or not is bunk. I was on it for 2 days and took 200mg each day. I did not really feel any sides at all, except for the fact that I had to pee a lot more than usual. I was surprised at how much fluid I was peeing out. Much more than if I took caffeine. The scale has not changed too much. When I woke up today, I noticed my muscles were extremely flat. Another strange thing is that the persistant DOMS I had in my left arm disappeared. It looks like I might have actually lost some muscle too. I suppose I should expect something like that if it's going to put me in a highly catabolic/underfed state. I am worried though that maybe if it is bunk that if they just gave me T3 which eats away muscle and very little fat. I think I'm going to stop taking it today and maybe continue it another time.

 

[RovinC]

You took it for only 2 days?
You need to research DNP more as at only 200mg/day it will take several days to see/feel anything
And it actually makes you hold water, so you may appear less defined.
If it were T3, dont you think youd feel an effect of that?
And if it were, I dont think it would eat away your muscle in 2 days.

Give it a week or more at that dose and see any sides. Also crystal did nothing for me compared to powder.
Crystal took a week + to feel anything, powder about 3 -4 days.

What did you expect in 2 days?

 

[ericraven2003]

You took it for only 2 days?
You need to research DNP more as at only 200mg/day it will take several days to see/feel anything
And it actually makes you hold water, so you may appear less defined.
If it were T3, dont you think youd feel an effect of that?
And if it were, I dont think it would eat away your muscle in 2 days.

Give it a week or more at that dose and see any sides. Also crystal did nothing for me compared to powder.
Crystal took a week + to feel anything, powder about 3 -4 days.

What did you expect in 2 days?

Exactly. DNP works great, but its not freaking magic.

 

[dfein]

You took it for only 2 days?
You need to research DNP more as at only 200mg/day it will take several days to see/feel anything
And it actually makes you hold water, so you may appear less defined.
If it were T3, dont you think youd feel an effect of that?
And if it were, I dont think it would eat away your muscle in 2 days.

Give it a week or more at that dose and see any sides. Also crystal did nothing for me compared to powder.
Crystal took a week + to feel anything, powder about 3 -4 days.

What did you expect in 2 days?

That might explain why I was peeing alot. I don't know what T3 feels like since I've never taken it, but I do know that the majority of weight lost on T3 is muscle. It's just that I've never seen my muscle react this way. It looks like the diameter of my arms shrunk. This could be a normal reaction because of DNP raising the metabolism. It could be that glycogen was depleted causing muscle to get smaller or it could be protein loss. I'm just going to stop for a couple of days and see if my muscle returns back to size. Also, I came down with a bad throat infection. I don't think the DNP had anything to do with it, but I want that to go away before I start again.

 

[shm772]

Be patient. I was on 250 mg crystallized for 4 days then went up to 500 on 5th day on the 9th day the sides hit me. horrible body aches, headache, fatigue, very pronounced unwell feeling then came the rash. The only thing I felt prior to this was heat which wasn't to bad. The sides? well they were hell. I still have 100 or so more caps. If I do it again I am staying at 250 mg the whole time. It took 3-4 days to finally feel normal and the rash about a week to fully clear up. Keep asking for the sides and they will come and then you'll wish you never left your mothers womb. Conc. if I do a low dose (250mg) per day the entire time how long should I run it?

 

[dfein]

I'm about to start again tomorrow. I had a throat infection which went away and turned into a cold. This time I'm going to stick with it at 200mg a day.

 

[gstay]

Be patient. I was on 250 mg crystallized for 4 days then went up to 500 on 5th day on the 9th day the sides hit me. horrible body aches, headache, fatigue, very pronounced unwell feeling then came the rash. The only thing I felt prior to this was heat which wasn't to bad. The sides? well they were hell. I still have 100 or so more caps. If I do it again I am staying at 250 mg the whole time. It took 3-4 days to finally feel normal and the rash about a week to fully clear up. Keep asking for the sides and they will come and then you'll wish you never left your mothers womb. Conc. if I do a low dose (250mg) per day the entire time how long should I run it?

Just a note about your rash SHM.

I too have horrible horrible DNP allergies a few days after my cycles.

The first time, It was bad and lasted about 4 days.
No amount of benadryl would make it subside.

My second cycle was supposed to be a 20 day low dose cycle.
Took benadryl everyday to dimish the rash at the end.
Had to cut it after 8 days because the rash was so bad. It was 10 times worse than the first time.
rash lasted about 8 days.

Finally found Reactine. Which is the strongest OTC anti-histamine sold in canada.
It's called Zyrtec in the US.

This cleared up my rash in less than a day.

Just thought I'd share the news for those who have allergies and can't find anything to deal with them.

Back doing a 2 cap a day cycle now, at the first sign of itching, i pop a reactine and it goes away in a few hours. Good stuff.

 

[dfein]

Unfortunately, I think my DNP is bunk. I've been on it for 7 days at 200mg with absolutely no effect. I got it from 0318 labs. I took a look around on the forum, and it seems I'm not the only one who didn't feel anything from their stuff either.

 

[Lizard King]

A few people here were reporting that they were under dosed. Never used them myself so I cannot really comment. 200mg is not a huge dose. I do feel sides at 200mg of powder but they are not intense sides and I can still function through a daily routine.

Have you had any weight loss in the 7 days?

 

[dfein]

A few people here were reporting that they were under dosed. Never used them myself so I cannot really comment. 200mg is not a huge dose. I do feel sides at 200mg of powder but they are not intense sides and I can still function through a daily routine.

Have you had any weight loss in the 7 days?

I had slight weight gain actually, but nothing crazy (which is normal for me despite exercise & diet and the reason I wanted to try DNP). I really did not feel a thing. It was as if I was taking nothing at all. I may give it another try with a higher dose, but I don't think it'll matter.

 

[Conciliator]

I may give it another try with a higher dose, but I don't think it'll matter.

If you're not experiencing any effect, than it doesn't hurt to keep gradually increasing the dose (granted you're not talking something else that's toxic at higher doses). I'd keep increasing the dose (while you have no effects from it) until you're somewhere around a supposed 800-1000 mg/day. At that point, you can safely say that you got ripped off and next time you can use one of the more reputable sources.

 

[buddy1]

Right before the ambulance comes to pick you up.

j/k