how much does t3 increase bmr?

Branco

Banned
say you take 50mg split into 12,5mg at differemt points of the day

how much would that increase your calorie output if your baseline t3 was at the middle of the reference range
 
I guess this is the best data there is to answer this question:

A trend was also seen for a direct correlation between REE/LBM and increases in fT3 levels, with an average 0.11 kcal/kg/d increase in REE/LBM for each 10 pg/dL increase in fT3.

Now try to guestimate the corresponding increase in fT3 by t3 supplementation and you're good to go.
 
fT3-50mcg-dose-T3.png

Nice, this is interesting! This is the average time-course for fT3 in healthy euthyroid adults given a single 50µg oral dose of T3 (Liothyronine) [1]. You should tie this in with Peter Bond's REE/LBM findings.

This is just an average, one PK paper from Goede et al. shows how individualized responses are [2].
_____
References:
[1] Jonklaas, J., Burman, K. D., Wang, H., & Latham, K. R. (2015). Single-Dose T3 Administration. Therapeutic Drug Monitoring, 37(1), 110–118. doi:10.1097/ftd.0000000000000113
[2] GOEDE, S. L., LATHAM, K. R., LEOW, M. K.-S., & JONKLAAS, J. (2017). HIGH RESOLUTION FREE TRIIODOTHYRONINE-THYROTROPIN (FT3-TSH) RESPONSES TO A SINGLE ORAL DOSE OF LIOTHYRONINE IN HUMANS: EVIDENCE OF DISTINCT INTER-INDIVIDUAL DIFFERENCES UNRAVELED USING AN ELECTRICAL NETWORK MODEL. Journal of Biological Systems, 25(01), 119–143. doi:10.1142/s0218339017500073
 
View attachment 150848

Nice, this is interesting! This is the average time-course for fT3 in healthy euthyroid adults given a single 50µg oral dose of T3 (Liothyronine) [1]. You should tie this in with Peter Bond's REE/LBM findings.

This is just an average, one PK paper from Goede et al. shows how individualized responses are [2].
_____
References:
[1] Jonklaas, J., Burman, K. D., Wang, H., & Latham, K. R. (2015). Single-Dose T3 Administration. Therapeutic Drug Monitoring, 37(1), 110–118. doi:10.1097/ftd.0000000000000113
[2] GOEDE, S. L., LATHAM, K. R., LEOW, M. K.-S., & JONKLAAS, J. (2017). HIGH RESOLUTION FREE TRIIODOTHYRONINE-THYROTROPIN (FT3-TSH) RESPONSES TO A SINGLE ORAL DOSE OF LIOTHYRONINE IN HUMANS: EVIDENCE OF DISTINCT INTER-INDIVIDUAL DIFFERENCES UNRAVELED USING AN ELECTRICAL NETWORK MODEL. Journal of Biological Systems, 25(01), 119–143. doi:10.1142/s0218339017500073
Ug ? You mean mcg.
 
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