increase the absorption of oral AAS?

[DinoBB76]

Hello everyone

does anyone have experience on how to increase the absorption of oral AAS?

empty stomach or after a meal?

with caffeine? , with piperine?

any suggestions? Thanks everyone

 

[tcri]

Sublingual adminstration is one way that this is accomplished. I wouldn't have any data about how much this increases absorption, but it works with many medications.

 

[laclark89]

Grapefruit juice?

 

[mochul]

Grapefruit juice?

It doesn’t affect the absorption. It lower metabolism rate so you are getting more out of the same mg.

 

[laclark89]

It doesn’t affect the absorption. It lower metabolism rate so you are getting more out of the same mg.

So u are basically absorbing more mg’s or concentrations than u would without the juice?

Absorption and being bio available is basically the same thing to me in my basic understanding.

 

[mochul]

So u are basically absorbing more mg’s or concentrations than u would without the juice?

Absorption and being bio available is basically the same thing to me in my basic understanding.

At the end yes higher absorption and lower metabolism rate achieve higher blood concentration. But the mechanism is different.
The juice is inhibiting enzymes responsible for the metabolism of drugs, mostly from cyp family and that can effect other drug metabolism too.

 

[nolan554]

There are some reports claiming that using higher percentages of magnesium stearate as an excipient might interfere with the absorption of certain compounds. I remember someone complained about Cialis regarding this issue

 

[SenorSuperdrol]

If you want more drugs out of your drugs, just take more drugs.

 

[Ghoul]

Taken with a high fat meal. Eggs and cheese, for instance.

AAS are fat soluble, like many drugs, and absorption goes up significantly in the presence of fats.

 

[laclark89]

Taken with a high fat meal. Eggs and cheese, for instance.

AAS are fat soluble, like many drugs, and absorption goes up significantly in the presence of fats.

makes sense, at least I will make sense of it because I like some fats in my diet they are essential after all. Plus I think a well balanced diet is where it’s at for most people, and not exactly the bs nutritional pyramid we all leaned in school or health and nutrition class, that diet is for obese people or marathon runner’s.
Should be imo for muscle and strength building look more like this for most , of course some will need more carbs depending. “ sorry for my bootleg white board example lol.
Testosterone is, but also estrogen and cortisol are also lipid derived hormones , or “coming from cholesterol”?

So the estrogen and cortisol are also slightly elevated with a higher fat diet?

 

[Liter O' Test]

Taken with a high fat meal. Eggs and cheese, for instance.

AAS are fat soluble, like many drugs, and absorption goes up significantly in the presence of fats.

so grinding up pills and parachuting them with 2 sugar free monsters is not ideal?

We should be putting our pills inside of a piece of cheese like how you give a dog its medication?

 

[DECLAN]

If you want more drugs out of your drugs, just take more drugs.

Hence, why his handle is not just your regular Mr.Superdrol.

 

[DECLAN]

Taken with a high fat meal. Eggs and cheese, for instance.

AAS are fat soluble, like many drugs, and absorption goes up significantly in the presence of fats.

Then just chase it with a glass of EVO or MCT lol

 

[bigboy420]

Doesnt L-carnatine do something like that?

 

[AlexDavis43]

Should be imo for muscle and strength building look more like this for most , of course some will need more carbs depending. “ sorry for my bootleg white board example lol.View attachment 291223

For bodybuilders, carbs are gonna be the base of that pyramid by far.

I don't know of many other than low carb dieters who eat more protein than carbs. Maybe some BBers pre-competition.

 

[Methyltst1993]

on an empty stomach before meals like many other medicines. Basically, it's the same: tablet steroids are always absorbed even after a meal and on an empty stomach.

 

[Spaceman Spiff]

I would check the bioavailability of orals, if it's 97%. It's not gonna be that big of a difference to "maximize" it

 

[OldGHGuy]

Coffee (caffeine) likely increases the uptake of Oxandrolone according to my own personal experience as well as studies such as this:

https://www.adop.pt/media/4114/Oxandrolone_excretion_effect_of_caffeine_dosing_.pdf