Can any antiallergic agent be used with Clenbuterol or just ketotifen?
MESO-Rx
Anabolic Steroids
Ketotifen and Clenbuterol
- Thread starter gilmarpersonal
- Start date
For what? Receptor re-regulation?
Yes, if that is what he is asking, i just use the Zquil form of benadryl... cheap, easy, effective.
Yeah, it's for preventing desensetize b2 receptors but from what i can find even if b2 receptors desensetize and you lost the jitters and the CNS stimulation, b3 receptors do not desensitize and lipolysis continue even without ketotifen or benadryl. I'm planning to run it 20mcg for 2 weeks and then 40mcg for another 4-6 weeks without ketotifen and benadryl in about a or so month, to end it along with my cutting.
Ive heard it has to be ketotifen. Kurt haven & Dr dean st mart have a video on clen talking about why benadryl doesnt work. Unfortunately real ketotifen seems pretty hard to find. Using it now but not sure it's legit same with the ketotifen I got last year from somewhere else.
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It certainly works. No need to dump money on Ketotifen when Benadryl is roughly 2 pennies a dose.
bighunanballs
Well-known Member
i dont believe Diphenhydramine has been shown to increase β2 receptor density on lymphocytes same as Ketotifen has. which is specifically what we are after with Clen/Keto use.
Bumpygooch
Well-known Member
Last I read about the receptor issue with clen, from Lyle McDonald who quoted a study(I’m actively trying to find it). It was mentioned previously, in layman’s, it’s doesn’t lose effectiveness, you just stop feeling the sides. Again, I’m trying to locate the study, just passing along what I read recently.
Ghoul
Well-known Member
Correct. Asthma patients don't "take breaks" or other drugs to resensitize receptors in order for clen to keep air passages open, which contributes to faster metabolism.
The enhanced lipolysis is a direct effect of clen on fat cells, which isn't subject to desensitization.
You lose the extra couple hundred calories burned off from your heart racing and trembling like you've got parkinson's.
bighunanballs
Well-known Member
its the shakes that the Keto directly effects if i remember from Todd Lee and also the kurt havens/dean st martin video. the shakes are the anti-catabolic/anabolic affects of clen but im possibly remembering that incorrectly
If i remember correct they were saying until you exceed a certain dosage of around 80mcg there's no downregulation at all, beyond that some downregulation occurs but only to one receptor, i think the b2, while b3 continues the lipolysis, or vice versa for the receptors, i don't remember exactly.
With simple words, even without ketotifen or benadryl and even if you go very high in dosage most likely after some time you won't feel the jitters and the CNS stimulation that much but the fat burning effect continues.
Ghoul
Well-known Member
The anabolic effect's been demonstrated in denervated and immobilized muscles to stop muscle wasting and even increase mass (with no associated increase in strength), and the sensitivity to this effect is greater the less stimulated the muscle is. So it could be useful for keeping an immobilized patient from wasting away spending months bedridden.
How much there is to gain for someone who's exercising, or just functioning normally with their nerves keeping muscles stimulated hasn't been demonstrated in anything I've been able to find.
^This.
If the "receptors are tired of the drug" thing worked like this there would be massive swaths of pharmaceuticals that simply would stop working with their patients dying due to the effect.
