It's already well known that orals are essentially liver poisons that confer the risk of many types of serious liver diseases, but now some (eg Scott Herman) are making the claim that injectables (even just test ester) can also cause it.
From what I've seen in pubmed, injectable nonbioidenticals, nandrolone in particular, have been shown many times to cause lots of liver stress. Nandrolone in particular does it via AR receptor signaling and by oxidative stress. However, just in the case of test-only usage causing serious liver disease, there doesn't seem to be much right now. The only thing there is for that is this case report:
pubmed.ncbi.nlm.nih.gov
This case report alone certainly isn't enough evidence, but there is lots of other literature about AAS and liver disease that has come out in the past few years. Doctors might encourage more thorough liver screening...and those of you taking trt or something might want to ask for it, especially if you've experimented with orals in the past or still do. Death by HCC or cholangiocarcinoma is worse than you can imagine.
Obviously people like Scott Herman have a vested interest in AAS not becoming even more popular than they already are, so you can't trust people like him either. It is a good idea to always be learning and quite literally "do your own research" about it...
From what I've seen in pubmed, injectable nonbioidenticals, nandrolone in particular, have been shown many times to cause lots of liver stress. Nandrolone in particular does it via AR receptor signaling and by oxidative stress. However, just in the case of test-only usage causing serious liver disease, there doesn't seem to be much right now. The only thing there is for that is this case report:
Development of Liver Cancers as an Unexpected Consequence of Anabolic Androgenic Steroid Use - PubMed
Although the relationship between androgens and hepatocellular tumor development has been noted since 1975, cases involving hepatocellular carcinoma (HCC) or cholangiocarcinoma development in patients on chronic androgen therapy or anabolic androgenic steroid (AAS) use are few, and far between...
pubmed.ncbi.nlm.nih.gov
This case report alone certainly isn't enough evidence, but there is lots of other literature about AAS and liver disease that has come out in the past few years. Doctors might encourage more thorough liver screening...and those of you taking trt or something might want to ask for it, especially if you've experimented with orals in the past or still do. Death by HCC or cholangiocarcinoma is worse than you can imagine.
Obviously people like Scott Herman have a vested interest in AAS not becoming even more popular than they already are, so you can't trust people like him either. It is a good idea to always be learning and quite literally "do your own research" about it...
