Low Lh, Fsh, Testosteron And Thyroids And High Prolactin

[pepous]

Hello,

I would like to consult with you my case. I am looking for threating many years already. I will subscribe my history bellow. I would be glad for any help or ideas.

My stats:
Age: 24
Height: 180 cm
Weight: 76 Kg

My sympthoms: (I suffer from this from puberty)
1. Lethargy and low energy level (sometimes I have energy and sometimes I am really fatigued - excercising and good low fat diet helps very much in this)
2. Very fatigued after food (not just normal food comma)
2. Non agresitivy - I am really very non assertive. I am scared sometimes of people
3. Anxieties
4. Anemia symptoms
5. Can gaint muscles
6. Low libido
7. Coldness
8. Psoariasis on my face
9. Cold hands

My history:

Blood test 1 (2 years or more old) - Not any drugs - Measured in early morning

LH 2,5 U/L <1,2 - 8,6>
THS 3,32 mU/L <0,34 - 5,60>
Free T4 10,1 pmol/l <7,9 - 16,0>
Free T3 5,1 pmol/l <3,8 - 6,0 >
T4 total 90,01 nmol/l <78,00 - 157,00>
T3 total 1,68 nmol/l <1,34 - 2,73>
FSH 2,7 U/l <1,3 - 19,3>
Estradiol 130 pmol/l <0 - 173>
Prolaktin 408,7 mIU/l <56,0 - 278,0>
Testosteron 14,1 nmol/l <6,1 - 27,1>
SHBG 25,0 nmol/l <13,2 - 89,5>
FAI ( free androgen index ) 56,4 % <22,2 - 110,2>

Blood test 2 (2 years or more old) - Not any drugs - Measured in early morning

UREA = 6.7
KREAJ=92
EGFRM1=1,42
BIL = 8.3
ALT=0.59
AST=0.38
CRP=0.7
PGLU=4.51
CHOL=4.56
LDL=2.89
Prolactin=22.93 (ref. range is up to 15 doc sayed)
U-GLU=normal
U-PROT=stopy
U-BIL=negative
U-UBG=normall
U-PH5=5.5
U-Blood=Negative
U-NITR=Negative
U-LEURO=2 (higher than range)


Blood test 3 - This blood test was done 3 hours after I woke up - Prolactin is now lowered

IGF-1 290 <265-410>
STH 0,03 <0-20>
SHBG 38.1 <12-75>
LH 2.26 <1,5-9,3>
FSH 2.43 <1.4-18.10>
Prolactin 12.04 <2.1-17.7>
Estradiol <0.09 <0.04-0.19>
Korizol 504 <118-618>
Testosterone 12.5 <5.4-30.4>
T4 - free 15.9 <11.5-22.7>
TSH 1.707 <0.5-4.9
ACTH 28.2 <10-60>

MRI results

According to my PRL levels doc did MRI of my pituitary. There was found small 2mm pituitary microadenomas. But doc said becouse of my hormones are in range it is no needed to deal with it.

My doctor suspected prolactinomas due to higher prolaction levels. In the second blood test prolactin was re-checked and was increased again. Than doctor did MRI where was found small 2mm microadenomas on pituitary. On the third blood test doctor said I should go on test at least 3 hours after I wake up. On this third blood test prolactin was in range (so prolactin is not my problem according to my doc.


Blood test 4 (no drugs in the body)

Na 141 <136-145>
K 4,1 <3,5-5,1>
CI 104 <98-107>
Ca 2,35 <2.15-2.55>
Mg 0.8 <0.66-1.07>
Cu 10.9 <12.4-20.6>
Zn 17.7 <7-23>
Glukosa 4.63 <3.33-5.59>
Fe 12 <10.6-28.3>


Blood test 5 (no drugs in the body)

Minerals
Na 142 <137 - 146>
K 4,3 <3,8 - 5,0>
CI 100 <97 - 108>
Ca 2,57 <2,00 - 2,75>
Fosfor anorg. 1,07 <0,65 -1,61>
Iron 26,1 <7,2 - 29>
Copper 15,3 <10,99 - 21,98>
Zinc 23,3 <9,1 - 13,7>
Osmolality 292 <275 - 295>
Ferritin 134,6 <22 - 322>
Glucose 4,6 < 3,9 - 5,6>

Urea 5,8 <2,8 - 8>
Kreatinin 95 <44 - 110>

Liver function tests
Bilirubin total 17,6 <2 - 17>
ALT 0,51 <0,1 - 0,78>
AST 0,37 <0,1 - 0,72>
GGT 0,25 <0,14 - 0,84>
ALP 1,01 <0,66 - 2,2>

Proteins

Albumin 50,6 <35 - 53>
Protein total 79,6 <65 - 85>

Lipids

Cholesterol 4,66 <2,9 - 5>
Triacylglyceroly 0,78 <0,45 - 1,7>
Cholesterol HDL 1,44 <1 - 2,1>
Cholesterol LDL 2,87 <1,2 - 3>

Hormones
IGF-I 342,9 <265 - 410>
STH 0,17 <0 - 20>
LH 1,41 <1,5 - 20>
FSH 2 <1,5-9,3>
Prolactin 16,59 <2,1 - 17,7>
Estradiol < 0,090 <0,04 - 0,19>
Progesteron 0,8 <0,9 - 3,9>
Cortizol 594 <118 - 618>
Testosteron 13,57 <5,4 - 30,4>

T3 total 1,45 <0,9 - 3>
T4 total 110,7 <60 - 150>
T4 Free 16,2 <11,5 - 22,7>
TSH 2,509 <0,5 - 4,9>
Anti Tg <15 <0,0 - 60>
Anti TPO 28 <0 - 60>

PSA 0,66 <0,0 - 1,4>
ACTH 40 <10 - 60>

Leukocyts 6,8 <4,1 - 10,2>
Erytocyts 5,44 <4,19 - 5,75>
Hemoglobin 164 <135 - 174>
Hematokrit 0,469 <0,390 - 0,510>

Blood test 6 (no drugs used - test was done at 3.2.2014)

Vit. B12 413 <141-489>
TSH 1,29 <0,27 - 4,2>
FT4 Free 16,5 <12 - 22>
FT3 Free 4,9 <3,1 - 6,8>
FSH 3,8 < 0 - 12,4>
LH 4,1 <1,7 - 8,6>
Estradiol 49,4 <28 -156>
Prolactin 10,79 <4,04 - 15,2>
Testosteron Total 15,25 <8,64 - 29>
Kortizol 292,6 <171 - 536>

MRI of my pituitary was done again and with no change. Still is there 2 mm microadenom.

Anastrozole experiment

At 6.2.2014 (February 6 2014)

I started using Anastrozole at dosing of 0,20 Mg / twice a week. My goal was to improve the testosterone and estradiol ratio, to boost LH, FSH and Testosterone levels .

At 17.3.2014 (March 17 2014)

Anastrozole dose: 0,2 MG / twice a week
Feelings: From the start of anastrozole test I felt much better, more asertive, more lean, had more energy, more libido.

I did new bloodwork test and results was: (The test was done at the same medical centre as a previsious one at 3.2.2014)

FT4 17,25 <12-22> +0,75 (compared to bloodwork done at 3.2.2014 - Before starding Anastrozole low dose protocol)
FT3 4,9 <3,1-6,8> +-0
FSH 4,5 <1,5-12,4> +0,7
LH 3,4 <1,7-8,6> -0,7
Estradiol 27,2 <28-156> -22,2
Testosterone 18,29 <8,64-29> +3,04

At 10.4.2014 (April 10 2014)

Feelings: Until this day I felt still much better (energy etc.). But at 10.4.2014 I started feeling anxiety, joint pain etd.
Anastrozole dose: 0,2 MG / twice a week up to the date 10.4.2014. Than skiped one dose and lowered dose to 0,15 / twice a week.

At 16.4.2014

Anastrozole dose: 0,15 MG / twice a week
I started feeling good again (energy, libido etc.)

At 28.4.2014

Anastrozole dose: still on dose 0,15 MG / twice a week
Feelings: I started feeling letargy etc.

At 2.5.2014
Anastrozole dose: still on dose 0,15 MG / twice a week
Feelings: I still felt the same. Anxieties etc.

Blood work results:

Estradiol 26,6 <28-156>
Testosteron 16,77 <8,64-29>

At 3.5.2014

Anastrozole dose: lowered dose to 0,1 MG / week
Feelings: Few days I felt better but ... Than it was wrong again.

Tried changing doses but never found sustainable dose where I have the benefits I had in first 2 monts of usage.

At 11.7.2014

From the date of 14 of June I didnt take any drugs. My blood work results are bellow:

Testosteron 18,85 <8,64-29>
Estradiol 79,2 <28-156>
LH 2,9 <1,7 - 8,6>
SHBG 32 <14,5 - 48,4>



At 28.7.2014

After few months of my anastrozole test I wantet to try it again. Due to it worked for 2 monts initially. So at 28.7.2014 I started using anastrozole again at the dose of 0,1 mg / 3 time a week

At 4.8.2014

I started feeling no benefits of anastrozole again. But still used the same dose of 0,1 mg / 3 times a week

At 7.8.2014

Feld still bad.
Anastrozole still the same

Blood test results:

Testosteron 20,88 <8,64-29>
Estradiol 29,2 <28-156>
Prolactin 8,83 <4,04 - 15,2>

From this moment I stopped anastrozole testing. Becouse I was not able to find right dose and becouse for me it probably worked only short term.


Next blood work results (no drug usage from 7.8.2014) - I was about one week after I had some viruss infection

TSH 2,1 <0,27 - 4,2>
FT4 free 14,9 <12 - 22>

LH 2,6 <1,7 - 8,6>
Testosteron 11,13 <8,64-29>
Estradiol 47,6 <28-156>
Prolactin 8,28 <4,04 - 15,2>
Early morning Cortisol 568 <171 - 536> (doctor checked as a possible culprit of my fatigue).

All these values were supressed. I believe it is due to I was not due to viruss infection not excecising and dieting.


What do you think about it? What do you recommend? I would be very glad if someone will review my case.

Thank you very much!

 

[tendency]

you ain't gonna like the answers pal..

 

[pepous]

?

 

[Dr JIM]

Now why don't you HIGHLIGHT those tests which fall out of the labs NORMAL REFERENCE RANGES, bc I failed to note ANY. But more importantly tell us what probably ALL of your DOCTORs have already said . . . . . . .. ????

 

[Dr JIM]

Fella has a 10 year history of complaints and is looking for answers" about whether a "virus" could be the cause of his NORMAL labs?

How about posting that all to important psychosocial history OP!

 

[pepous]

Fella has a 10 year history of complaints and is looking for answers" about whether a "virus" could be the cause of his NORMAL labs?

How about posting that all to important psychosocial history OP!

You believe my LH/FSH is not supressed or what are you talking about?

 

[Dr JIM]

I'm not sure what your referring to? Yes the LH and FSH levels DECLINED but they remain within the labs NORMAL RANGES, do they not?

Bc if that's the case your chasing a number fella and THAT is time wasted.
What have your doctors told you?

 

[Hormonal_Damage]

Pepous do you have sexual dysfunction? Can you get an erection?

If so don't waste your time thinking you have a hormonal problem because you obviously do not.

You need to go back to your gp and ask for a prescription of antidepressants.

 

[pepous]

My doctor told me that my testosterone is a little maybe supressed. But who know this can cause my sympthoms. As well as with thryoids.

You believe these values are normal? But it is true that sometimes my values are OK.

TSH 2,1 <0,27 - 4,2>
FT4 free 14,9 <12 - 22> (this should be according to guides higher than on half of the scale -> more than 17 should be OK -> it is bellow)
LH 2,6 <1,7 - 8,6> (this value is OK if my testosterone is not that low)
Testosteron 11,13 <8,64-29> (should be in higher one third of the scale)

My erections are weak. No morning wood. When I do have morning wood I feel better overal.

There are three possibilities:
1. I have some sympthoms but they are not related to hormones and I am only idiot looking for hormones as a culprit for 5 years which is not true. I am 5 years looking for something which is not true :-(. It is possible I cant be objective in this. If it is so it is hard to admint I am wrong.

2. My problems are related to hormones. I believe so becouse I know how I feel with more testosterone etc. that all my symthoms are gone etc. I know that I cant objectively gain muscles in compare to others do etc. (but honestly who doest feel better on testosterone -> but for me it is like day and night)

3. My problems are partly hormone related and partly in my brain. This is very probable.

So what should I do? Why anastrozole worked for me for few months?

 

[Hormonal_Damage]

pepous, when you say all symptoms disappear on testosterone does your libido improve do you get better erections?

What dose T do you take?

Your test level is great (20,88 <8,64-29>)

Do you masturbate a lot?

 

[pepous]

I did 250 mg / week cycle and felt great. Yes my testosterone was 20,88 but it is my all time high. Usually I have bellow 15. For example 7.8.2014 I had values:

Testosteron 11,13 <8,64-29>

I believe sport helps me to increase testosterone as well as good diet. But that doesnt mean that problem dissapear.


Also I personaly believe that my problem is combined. I have little supressed thyroids. If you have supressed thyroids than body cell are less sensitive to hormones. And I have also supressed testosterone which in altogether cause me my symthoms.

Testosterone alone as well as Thyroids alone can cause lethary etc. issues which I suffer from.

I am not hypogonadal either hypothyroids. But I have desclined both values which altogether can cause my symthoms I believe.

That is my theory. Am I wrong? My symthoms are real. I dont believe it is depression. It is physical (subjectively of course)

 

[blazinshotguns]

Your thyroid is fine . Your free t3 is at a good spot .
Do you masterbate the night before these test because that can raise prolaction

 

[pepous]

Your thyroid is fine . Your free t3 is at a good spot .
Do you masterbate the night before these test because that can raise prolaction

No I dont. My thyroids are sometimes good and sometimes are low. It is often bellow 50% of the scale (where it is supposed to be low).

 

[blazinshotguns]

No I dont. My thyroids are sometimes good and sometimes are low. It is often bellow 50% of the scale (where it is supposed to be low).

You should start supplementing iodine and start checking morning and afternoon temperature . You should hit 98.6 in the afternoon

 

[pepous]

I am usually 97,16 in the morning and 97,88 before I go to the bed. Sign of hypo. Hmm?

 

[blazinshotguns]

I am usually 97,16 in the morning and 97,88 before I go to the bed. Sign of hypo. Hmm?

Check it in the mid afternoon I think somewhere I read temperature drops before bed . Like check it now

 

[blazinshotguns]

Check it in the mid afternoon I think somewhere I read temperature drops before bed . Like check it now

Should be like mine

 

[Hormonal_Damage]

I believe this guy has a problem with his testosterone axis. I don't doctor by numbers.

He has symptoms at only 24 years of age.

Say bullshit to your labs. I believe you. You need help.

 

[toolman]

You should start supplementing iodine and start checking morning and afternoon temperature . You should hit 98.6 in the afternoon

Blazing I thought we told you to stop playing doctor. Doogie Howser you are not other than being a half pint in age...as in not even legal to buy a pint...and your focus on masturbation questions which leads me to believe you share a sexual orientation with the older Neil Patrick Harris

 

[blazinshotguns]

Blazing I thought we told you to stop playing doctor. Doogie Howser you are not other than being a half pint in age...as in not even legal to buy a pint...and your focus on masturbation questions which leads me to believe you share a sexual orientation with the older Neil Patrick Harris

Dude your not my dad , so kindly fuck off and quit riding my dick because it's really starting to hurt