Milk thistle

Ok Thanks Buddy is it ok to take it on top of these products as I have sum lying a round any way. Thanks 001
 
There is actually no proof that milk thistle or any other supplement protects your liver from aas. I think milk thistle reversed some of the damage from Tylenol, but thats it.. If there was a way to repair or protect your liver then every guy with hep c would be buying basket fulls.
 
Yeah but must be better then nothing is their any thing else like liv-52 I hear is good or any med's you recommended ?
 
Unless you're running orals you don't have a big concern over liver heath and even then unless you're running higher doses or for extended periods of time, imo you usually don't have much to worry about. Always exceptions to that but in general, either NAC or TUDCA would be good choices, Liv52 could be thrown in as well but isn't a replacement for either of those other two.
 
Ok Im only taking 30mg of debol a day and 250ml Test ,its my first cycle just thought you can never be to careful right. Plus this just start for me , I doubt it will be something I grow out of quickly. So I might as well learn and take best of care as much as I can. I wasn't always into fitness if you get me. Though im sure my liver is fine but any way.
 
How much to Take to Help protect your liver is one 1000 mg a day ok. Thanks 001

ZERO if your otherwise healthy and limit oral AAS to no more than 4-6 weeks on AND at least the same amount time off you will be fine mate. It's really much to do about nothing, IME. The fact is AAS associated hepatic injury is so damn rare, I wonder why anyone uses those "supplements"?

Did you "protect" your liver before you went out drinking?

Well the toxicity of AAS are very similar in many respects to ETOH and there is absolutely no evidence liver protectors provide any benefit whatsoever.

Regs
jim
 
^^^^
He's right..Tylenol maybe aas not so sure!!

I've not seen any studies on MT for APAP probably bc the antidote for TYLENOL toxicity is NAC.

That's not to say MT may not be beneficial in those patients whom have missed the optimal 24 hr therapeutic window for NAC.

(Some Toxicologists and Hepatologists believe NAC my be helpful for up to 72 post ingestion and in that respect MT might also be worth a try)

Understand I'm referring to patients with TOXIC APAP ingestions, in which the end result absent appropriate TX is fulminant liver failure necessitating a liver transplant.
 
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I was quite suprised to discover Acetaminophen overdose is the leading cause of acute liver failure in the developed world today. All in all , some of the possible effects at therapeutic doses are too much for me , never mind children, to whom its frequently prescribed. Inhibition of test production gentleman....

therapeutic acetaminophen dosages can still increase the blood concentrations of liver enzymes (markers of liver damage) (Watkins 2006). Other potential negative consequences of acetaminophen include increased fracture risk (Vestergaard 2012), inhibition of testosterone production (Kristensen 2011; Kristensen 2012), and kidney toxicity (Bessems 2001).
 
In spite of those side effects it's probably the most widely used analgesic, antipyretic to date. The hepatic toxicity is rarely a signiicant problem (does not result in fiver failure) in patients with chronic APAP "toxicity".

The treatment is to recognize the cause (the histology results are pathagonamonic) which is usually noted by reviewing all of a patients meds including OTC drugs, and discontinue it's use.

I doubt the other adverse effects you listed were derived from controlled studies, yet admittedly I've never investigated them as potential complications of APAP use,
 
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