Need Help. Lower Lab Results on Higher Doses

[Civdiv]

Racking my brain trying to figure out what's going on. I don't want to write a novel but I'll try to be as thorough as possible.

Past labs: all pins 2x week, pinned 2 days before lab draw

April 4th - baseline trt labs
test dose 100mg/wk
No gh
Total t 1080
Free t 277. 9
E2 48 (range 0-56,not ultrasensitive)
Shbg 30.7
Igf1 232

June 6th
Dose test/primo 300/100
Gh dose 4iu
Total test 2421
Free 634
E2 ultrasensitive 39 (0-29)
No shbg test
Igf1 329

Aug 1st
Dose test/primo 500/200
Gh dose 5-6iu. (6iu 4days a week before fasted cardio)
Total test 1455
Free 476
E2 ultrasensitive 33 (0-29)
No shbg
Igf1 232

Here's the variables...
From my high responses to test doses earlier in April and June I was taking Pharma grade test. After June 6th I switched to SSA test C 250. I also added Proviron 50mg/day. The primo was sent to jano and test perfect. I didn't send the test c.

From the June 6th labs I've dropped 20 or more lbs of fat from around 15-18%bf to around 12% Aug 1st Last labs were also done in an extreme calorie deficit, specifically carb deficit.

My first response was bunk gear. I just have a hard time buying that. With SSA's high volume, there would be a lot more people complaining if it was bunk. Also, why did igf-1 also drop below baseline on a higher dose. Igf1 is from the same ssa H36 order. My wife is taking the same gh and hers increased with each higher dose so it's not the gh. I also started noticing that I'd get little to no response from pre-workout TNE. Took 100mg once and barely felt anything. Tried TNE from 2 different sources.

I was experiencing what I thought was low E2 symptoms and assumed crashed from primo. I rode it out just to see what labs showed. I could get hard when I needed to, I just didn't want to. Zero interest in sex. Also lost all happiness in the things I used to enjoy and totally emotionally flat.

My last primo and Proviron dose was taken July 30th, 2 days before last labs. I'm on test only now and dropped test to 250/wk. I'm retesting on the 15th including shbg to see if dropping primo and Proviron will swing my test levels at all. Depending on results I'll swap gear and retest in 4 weeks. I've noticed my emotions starting to return and I'm staring a little more at my wife's ass when she walks buy now.

Any ideas of what could cause such a drop in test and gh levels other than underdosed gear?
What else should I be looking for. I don't want to reach too far until labs on Friday, but I already can't sleep from this cut and this just racks my brain when I wake up at 2am.

 

[RockyP]

My first thought is the UGL Test C is under-dosed. There's no other reason for your Test and E2 to be lower on 8/1 compared to 6/6 unless the Primo is legit (it is, you tested it), and the test is under-dosed. This would also explain the sexual side effects. I would not expect this to happen at 500 test / 200 primo if you were ok on 300 test / 100 primo. As far as the IGF-1 levels, that's a bit more complicated given the half-life of IGF-1 and the varying levels of E2 impacting conversion of GH to IGF-1.

I'd suggest going back to pharma grade, switching brands, or upping the dosage of Test C and re-checking labs. I'm not familiar with SSA but even reputable vendors can have batches that are off (but they should also not sell those or offer them at a discount). One vendor I saw recently had Deca 300 that tested at 230 or so.

 

[Civdiv]

Thanks man. Appreciate the response. I really don't see any way it's not underdosed. I would just think there would be more people screaming since it's from March from a high volume vendor.

I have 2 20ml vials of this batch I filtered months ago. I went for the second vial to check it out and it looks like it's crashing a little. Just cloudy swirls from sitting in a colder closet. I wonder if the one I've been using now did the same and I didn't notice it. Maybe pulled some of the crystals coming out earlier on and left a lower concentration? First month or so I wasn't heating before drawing. Is that even a possibility. It makes more sense that I fucked it up somehow than I'm the only person in 1000 that got a bunk batch. I'm totally reaching here. Just trying to make sense of it.

I'm going to pin from the new vial tonight. It's only 48 hours before labs but at least should see if my results are moving in the right direction.

 

[buck]

You used the same lab for all tests?
Labs make errors more then people think they do.
Without another test to see if there was an error on not no way to know for sure but seems likely the gear is underdosed. But i have had pharmaceutical test that i got from a US pharmacy give me weird results on occasion. Seems the the bodies ability to clear things out and the bodies ability to produce the ester needed to cleave off the ester from the test molecule may fluctuate too to some degree.

 

[Civdiv]

You used the same lab for all tests?

Thanks for the response.

Baseline labs were a different lab but the last two were from the same lab. I swapped to a different supplier's test and getting labs done tomorrow to see if the needle is at least moving in the right direction. Unfortunately the only way to know for sure is send it out the suspect test to jano. Hopefully pull the cash together for it next week.

Still throws me off that my igf1 was below baseline too when my wife's increased using the same vial. That and I would assume much lower E2 from that primo dose if test was that underdosed to give me those low numbers. Too many weird things going on to rack my brain around. Next step is going to have to be jano I guess.

 

[Civdiv]

So just wanted to post a follow up. I sent the suspect test to janoshik and it was good right around 250mg/ml.

This pretty much confirms info I read in other posts about crashed shbg lowering TT. I followed up with more labs to include shbg. After 2 weeks off everything it was 18.6 nmol/L (16.5-55). My baseline is 30.7. I'm sure it was lower earlier while on primo and Proviron. My results make more sense now.

Appreciate everyone who offered me help with this. It also helps now to better understand how I respond when my shbg is low, and that I should probably include it in future labs to get the whole story.