so I just learned something new, I've been on many regiments of prednisone and I understand a lot of people on here take it due to injury or any other complication. Turns it it can be reversed by supplementing chromium. I hate corticos and I'm sure you guys do too. But next time I have to take it I WILL be supplementing chromium.
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Reversal of corticosteroid-induced diabetes mellitis with supplemental chromium
DOI: 10.1046/j.1464-5491.1999.00004.x
Issue
Diabetic Medicine
Volume 16, Issue 2, pages 164–167, February 1999
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Aims To determine if the stress of corticosteroid treatment increases chromium (Cr) losses and if corticosteroid-induced diabetes (steroid diabetes) can be reversed by supplemental chromium.
Methods The effects of corticosteroid treatment on chromium losses of 13 patients 2 days prior to steroid administration and the first 3 days following treatment were determined. Since steroid-induced diabetes was associated with increased chromium losses and insufficient dietary chromium is associated with glucose intolerance and diabetes, we treated three patients with steroid-induced diabetes with 600 μg per day of chromium as chromium picolinate.
Results Urinary chromium losses following corticosteroid treatment increased from 155 ± 28 ng/d before corticosteroid treatment to 244 ± 33 ng/d in the first 3 days following treatment. Chromium supplementation of patients with steroid-induced diabetes resulted in decreases in fasting blood glucose values from greater than 13.9 mmol/l (250 mg/dl) to less than 8.3 mmol/l (150 mg/dl). Hypoglycaemic drugs were also reduced 50% in all patients when given supplemental chromium.
Conclusions These data demonstrate that corticosteroid treatment increases chromium losses and that steroid-induced diabetes can be reversed by chromium supplementation. Follow-up, double-blind studies are needed to confirm these observations.
Diabet. Med. 16, 164–167 (1999)
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Reversal of corticosteroid-induced diabetes mellitis with supplemental chromium
- A. Ravina1,
- L. Slezak1,
- N. Mirsky1,
- N. A. Bryden2 and
- R. A. Anderson2
DOI: 10.1046/j.1464-5491.1999.00004.x
Issue
Diabetic Medicine
Volume 16, Issue 2, pages 164–167, February 1999
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Keywords:
- chromium;
- corticosteroids;
- diabetes mellitis;
- glucose;
- insulin;
- steroid-induced diabetes mellitis;
- trace elements
Aims To determine if the stress of corticosteroid treatment increases chromium (Cr) losses and if corticosteroid-induced diabetes (steroid diabetes) can be reversed by supplemental chromium.
Methods The effects of corticosteroid treatment on chromium losses of 13 patients 2 days prior to steroid administration and the first 3 days following treatment were determined. Since steroid-induced diabetes was associated with increased chromium losses and insufficient dietary chromium is associated with glucose intolerance and diabetes, we treated three patients with steroid-induced diabetes with 600 μg per day of chromium as chromium picolinate.
Results Urinary chromium losses following corticosteroid treatment increased from 155 ± 28 ng/d before corticosteroid treatment to 244 ± 33 ng/d in the first 3 days following treatment. Chromium supplementation of patients with steroid-induced diabetes resulted in decreases in fasting blood glucose values from greater than 13.9 mmol/l (250 mg/dl) to less than 8.3 mmol/l (150 mg/dl). Hypoglycaemic drugs were also reduced 50% in all patients when given supplemental chromium.
Conclusions These data demonstrate that corticosteroid treatment increases chromium losses and that steroid-induced diabetes can be reversed by chromium supplementation. Follow-up, double-blind studies are needed to confirm these observations.
Diabet. Med. 16, 164–167 (1999)
View Full Article (HTML) Enhanced Article (HTML) Get PDF (248K)
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Copyright © 1999-2015 John Wiley & Sons, Inc. All Rights Reserved.
