Semaglutide and Metformin (HGH)

[dros]

I see alot of people nowadays incorporating Metformin (as well as T4/T3) with HGH to prevent insulin resistance

Can you use semaglutide instead. If I am reading correctly it does the same as metformin but better?

 

[hudson98]

No idea what that is, a datbtrue peptide?

You will be more than fine using berberine or metformin, many do. And track your AM glucose. Nothing else needed.

R-Ala, cardio, eating less carbs also improve insulin sensitivity. Fish oil too.

 

[HB_22]

Won’t work. Look, they dropped significant points in blood glucose levels in these semaglutide studies because of eating a LOT(!) less than before. Semaglutide itself does not lower blood glucose levels if you shuffle in the same high amount of carbs as you always did.

If you are dieting, however, it can be very helpful because you will feel full on very little food. If you are bulking or maintaining it will not provide a real benefit (if any benefit honestly).

 

[Rido]

Won’t work. Look, they dropped significant points in blood glucose levels in these semaglutide studies because of eating a LOT(!) less than before. Semaglutide itself does not lower blood glucose levels if you shuffle in the same high amount of carbs as you always did.

If you are dieting, however, it can be very helpful because you will feel full on very little food. If you are bulking or maintaining it will not provide a real benefit (if any benefit honestly).

No

Semaglutide increases insulin secretion and reduces glucagon secretion. Combining this with metformin can cause hypoglycemia.

Semaglutide can help with BG control...

Clinical potential of treatment with semaglutide in type 2 diabetes patients

Glucagon-like receptor agonists (GLP-1RAs) are included in current national and international guidelines as second-line treatment especially in patients with type 2 diabetes and concomitant cardiovascular disease (CVD). First-generation GLP-1RAs were ...

www.ncbi.nlm.nih.gov

Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial

Semaglutide is a glucagon-like peptide-1 analogue in development for the treatment of type 2 diabetes. Its effects on first- and second-phase insulin secretion and other measures of beta cell function and glycaemic control were assessed.In this single-centre, ...

www.ncbi.nlm.nih.gov

 

[Rido]

TBH I am currently using Semaglutide on a recomp because NPP made my appetite insatiable. It was hard to control.

MY BG has been under pretty solid control on 1mg of semaglutide and 6-8 units of HGH.

 

[HB_22]

TBH I am currently using Semaglutide on a recomp because NPP made my appetite insatiable. It was hard to control.

MY BG has been under pretty solid control on 1mg of semaglutide and 6-8 units of HGH.

Thanks for linking the studies. This is indeed interesting to know.