When liver enzymes are worrisome?

[Tanaz]

Hello,
I would like to know your opinion about this "mild" values of GPT and GOT.
Can you keep these values for a couple of months?
GPT Transaminases: 183 U/l (recommended < 41)
GOT Transaminases: 162 U/l (recommended < 40)
Someone has experience with these values?

I am hearing discording opinions...
From what I read, under 5 times it is not so an urgent matter:


But I would like to ask from your experience if it is something doable and I am worrying for nothing or not...

 

[Rido]

Your transaminase are drug induced but your liver enzymes shouldnt be that elevated. As I said before, drop the anavar, alcohol, or drugs hard on your liver. Increase fluid intake. There are other drugs other than var.



Do what you want though. This is your first cycle. It's not like you are going to run harsher cycles down the road(sarcasm)

 

[Mindslave]

Drop the drugs wait 3 weeks and get bloods dune again and you’ll have your answer,you could have a bit of a fatty liver as well which would be worsened but the drugs if your liver is fighting of drugs it can t properly deal with the fats. Take a few weeks or months to get a handle on what’s going on once your off the drugs if your values are still up your Dr will most likely send you for a ultrasound good luck with it brother

 

[juicebro]

ALT and AST elevations up to 5 fold happen in health natural people who exercise hard (for weeks after). GGT doesn't increase with exercise so you might want to get more markers checked if you are worried.

 

[kosp]

Your transaminase are drug induced but your liver enzymes shouldnt be that elevated. As I said before, drop the anavar, alcohol, or drugs hard on your liver. Increase fluid intake. There are other drugs other than var.



Do what you want though. This is your first cycle. It's not like you are going to run harsher cycles down the road(sarcasm)

First, you gave him harm reduction advice.

Then you influence him with your B&C and TRT mindset, cool.

 

[M@NU]

ALT and AST elevations up to 5 fold happen in health natural people who exercise hard (for weeks after). GGT doesn't increase with exercise so you might want to get more markers checked if you are worried.

this
there are studies of marathon runners having values of over 1k after their run.
If you want somewhat reliable values, take 5-7 days off prior to your blood test.
Working out can scew a lot of values (ALT/AST/CK, stuff like myoglobin in urine, protein in urine etc.)
GGT is way more reliable since it is a almost exclusive liver specific enzyme while ALT/AST are specific to a lot of organs and muscle tissue

 

[Rido]

ALT and AST elevations up to 5 fold happen in health natural people who exercise hard (for weeks after). GGT doesn't increase with exercise so you might want to get more markers checked if you are worried.

AST more specific to exercise. ALT is not as much.

I look at blood work all the time and haven't seen that in people who workout.

First, you gave him harm reduction advice.

Then you influence him with your B&C and TRT mindset, cool.

You again?

Keep trolling posts.

I didn't suggest anything about blast/cruise or TRT.

I said don't drop the anavar. No reason to start laying out damage on the first cycle

 

[kosp]

AST more specific to exercise. ALT is not as much.

I look at blood work all the time and haven't seen that in people who workout.
You again?

Keep trolling posts.

I didn't suggest anything about blast/cruise or TRT.

I said don't drop the anavar. No reason to start laying out damage on the first cycle

AST more specific to exercise. ALT is not as much.

I look at blood work all the time and haven't seen that in people who workout.
You again?

Keep trolling posts.

I didn't suggest anything about blast/cruise or TRT.

I said don't drop the anavar. No reason to start laying out damage on the first cycle

Just because you ran those harsher cycles down the road doesn't mean we all are going to do that, I am not doing that, you feel so entitled to say such things but that is YOUR experience, and I don't care how old are you, those kind of assumptions are arrogant.

 

[Rido]

Just because you ran those harsher cycles down the road doesn't mean we all are going to do that, I am not doing that, you feel so entitled to say such things but that is YOUR experience, and I don't care how old are you, those kind of assumptions are arrogant.

I didn't say I did


Every harsher past cycle 1 are typically harder on the most than 1.

People rarely run less compounds than the previous cycle.

 

[M@NU]

AST more specific to exercise. ALT is not as much.

I look at blood work all the time and haven't seen that in people who workout.
You again?

Keep trolling posts.

I didn't suggest anything about blast/cruise or TRT.

I said don't drop the anavar. No reason to start laying out damage on the first cycle

both are enzymes which are also found in sceletal muscle tissue
check this study:

Muscular exercise can cause highly pathological liver function tests in healthy men - PMC

To investigate the effect of intensive muscular exercise (weightlifting) on clinical chemistry parameters reflecting liver function in healthy men. Fifteen healthy men, used to moderate physical activity not including weightlifting, performed an 1 h ...

www.ncbi.nlm.nih.gov

 

[Rido]

both are enzymes which are also found in sceletal muscle tissue
check this study:

Muscular exercise can cause highly pathological liver function tests in healthy men - PMC

To investigate the effect of intensive muscular exercise (weightlifting) on clinical chemistry parameters reflecting liver function in healthy men. Fifteen healthy men, used to moderate physical activity not including weightlifting, performed an 1 h ...

www.ncbi.nlm.nih.gov

Saying one is more specific and the other isn't doesn't mean both won't be elevated.


Look at this more recent study.

Very interesting one as AAS and bodybuilding is part of to

Body Building and Aminotransferase Elevations: A Review

In addition to liver injury, elevation of aminotransferases can be caused by strenuous exercise and use of muscle-building and weight-loss supplements. The purpose of this review is to discuss the various mechanisms of elevation of aminotransferases related ...

www.ncbi.nlm.nih.gov

 

[Deezznutzz]

1200mg nac daily dramatically lowers my liver enzymes. Over 20 labs to back mine up on nac. Only over 1-8 points over once or twice in 2 years now with nac.... on orals and blast. Before Nac I'd test over all the time just training natty. I don't lift 3 days before labs nowadays.

 

[M@NU]

Saying one is more specific and the other isn't doesn't mean both won't be elevated.


Look at this more recent study.

Very interesting one as AAS and bodybuilding is part of to

Body Building and Aminotransferase Elevations: A Review

In addition to liver injury, elevation of aminotransferases can be caused by strenuous exercise and use of muscle-building and weight-loss supplements. The purpose of this review is to discuss the various mechanisms of elevation of aminotransferases related ...

www.ncbi.nlm.nih.gov

you are right.
I guess ive misinterpreted your post. I thought you wanted to express that ALT is not but you said "not as specific as AST"
Interesting study indeed.
I am also pretty sure that there are huge individual differences on how impactful excersise is on those values.
Me for example:
lets say bloodtest is friday.
If i train Friday-Thursday and then go to the bloodtest, i know that my ck will not be below 3000 and my ALT/AST will be above 200.
Other guys can workout with the same intensity/split/volume etc, go to bloodwork and come out with Ck of 500 and ALT/AST of 70

 

[Millard]

If you want somewhat reliable values, take 5-7 days off prior to your blood test.

It only takes me 2-3 days to return to normal range but my ALT/AST are never quite more than 2x normal from heavy training.

 

[M@NU]

It only takes me 2-3 days to return to normal range but my ALT/AST are never quite more than 2x normal from heavy training.

yeah, thats what ive meant with individual differences.
not sure if this has to do with regeneration capabilities or if there are individual differences between indcuded muscle damage during a workout or whatever.
Ive had this topic some years ago on PM board and it is fascinating how different people react to working out.
Same with myoglobin / protein in urine. Some get ++ on the combur test strips after a workout, some get nothing

 

[Pounds23]

Hello,
I would like to know your opinion about this "mild" values of GPT and GOT.
Can you keep these values for a couple of months?
GPT Transaminases: 183 U/l (recommended < 41)
GOT Transaminases: 162 U/l (recommended < 40)
Someone has experience with these values?

I am hearing discording opinions...
From what I read, under 5 times it is not so an urgent matter:
View attachment 250861

But I would like to ask from your experience if it is something doable and I am worrying for nothing or not...

Hey brother first I would drop any orals then if ur running any toxic injectables like tren also drop that. You wanna make sure ur drinking fluids but u also don't wanna over do fluids. Before u pull anymore blood again I would take atleast 5-10 days off the gym let ur body fully recover. I would look into getting on some health supps they aren't magic but there worth taking things like omega-3 dhea, you also should grab a liver supp that has stuff like milk thistle,tudca/udca,nac and a few other supporting supps. You could also have a scan done to see if u have non alcoholic fatty liver. It's actually something I'm dealing with and I don't drink any alcohol or do any drugs. But when covid hit I went into a pretty bad depression and got pretty out of shape cause I was also dealing with a pretty bad injury to my back thankfully which has recovered not 100 percent but 95-98 percent. But my diet went to shit and I just added bodyfat more then usual for me. Another supp that honestly does azing things for the liver is gluthione. Alot of places have it but only in 600mg vials in lypolized powder. They do make kits you have to ask and look around but get urself some of that and start pinning it there was some recent study's of people with liver damage really bad damage and they used gluthione is high doses iv and it regenerated there liver and brought numbers way down. It is definitely something worth using iv noticed a pretty big difference in my numbers and I have a scan coming up in a month buty numbers are back down from 80 to 40 since I incorporated everything.... I do use revivesupps then for the gluthione the best one I could find and for the price was amino-asylum. I would prefer to get pharma grade lypolized powder gluthione but I haven't really been able to find a src that has kits that I trust. And alot of others only have one lypolized vial of 600mg for like 20$+ a vial.... For me that about 3 days worth so not worth it really for me. I don't think if u come down to say trt it'll effect ur numbers it didn't with me. I stayed on 125mgs of test cyp and was able to bring things back down the big thing fore also was dropping the body fat.... Now I'll know more when I go for the scans and they compare before to after...... Also there is some clinics now that offer just injectable vitamins and amino therapy treatment. So u could actually get ur gluthione from there it'll be alil more but it'll be pharma grade and quailty. Also there is plenty of other brand then revivesupps that off liver and kidney products that are just as good. But give urself atleast a month off the orals and if it using any rec drugs or drinking cut that out as well for atleast a month and leading up to the bloods take atleast a week off of the gym and get them redone and see how they come back. If they haven't improved then go see ur doctor and ask for a MRI or sonogram of liver and really u could do ur kidneys as well that will give u a better idea of the size multiple things.... It's probably just from using orals and training hard and if ur drinking or taking anything else cut those out and u should see some improvements in a 4-6 weeks....

 

[trengod1992]

I don’t cycle extremely hard on my last blast before I got off everything to get my fertility. My alt and ast was in the 80s. That was on 300mg test 225mg tren e and 50mg of anavar. After seeing that on my mid cycle blood work I started taking liv52 two pills a day for a month and all my levels went down to the normal mid 30s

 

[Fat]

I would try 500mg TUDCA AM and PM and retest your bloods in 4 weeks.