ITPP

[heady muscle]

Subbed to be edjumacated.

 

[Nutpuncher]

I am sure you either found this by now..... There's handful of products from this website that looks interesting.

https://racehorsemeds.com/product-category/itpp-2/.

 

[Bob Dole]

Well if you change your mind, there's not much to making a solution. It's water soluble so you can use some ba water and then transfer it to a sterile vial with a millipore:
Whatman 6900-2502 GD/X 25 Sterile Syringe Filter, 25mm, 0.2 Micron, PVDF Filtration Medium, Pack of 50: Science Lab Syringe Filters: Amazon.com: Industrial & Scientific
There are cheaper syringe filters but those are the cleanest and nice to have on hand.

I have considered it, but those filters are a big investment for something I am just looking to try for now to see if I get good results.

 

[Bob Dole]

I am sure you either found this by now..... There's handful of products from this website that looks interesting. https://racehorsemeds.com/product-category/itpp-2/.

I have seen that, I have found a source (not in America) that currently makes a liquid version not intended for horses, just on the fence about ordering it still.

 

[Pomacanthidae]

I have seen that, I have found a source (not in America) that currently makes a liquid version not intended for horses, just on the fence about ordering it still.

I'll order and be a Guinea pig lol

 

[Dr JIM]

My only concern is does/should it be kept cold once its been converted into a solution form?

ALL peps oxidize quite readily and should be refrigerated after recon.

But if that's your only concern think again.

Like how about its efficacy, safety and or sterility for starters.

It's shocking how some so willing to accept the risk associated with such compounds when Big Pharma has been sued for much less.

You might also want to know the dose used in mice ranged in the GRAM/KG range!

 

[Bob Dole]

ALL peps oxidize quite readily and should be refrigerated after recon. But if that's your only concern think again. Like how about its efficacy, safety and or sterility for starters. It's shocking how some so willing to accept the risk associated with such compounds when Big Pharma has been sued for much less.

@Dr JIM, thanks for replying, I always hope you will chime in when I post. Your points are very valid and a big factor with why I haven't ordered yet. So what would your suggestion be? To be honest I have never tried to do something like convert a substance like this into a liquid version so I am very hesitant and to be blunt afraid to try. lol

 

[Dr JIM]

Now let's see I just noted it's being sold at 20mg/ml aliquot vials so IF you weighed on 70kg you would require a whopping 3500 VIALS to reach the transgenic mice study 1g/kg dosage.

Now why do you think those mice were SACRIFICED at the studies conclusion, LMAO!

 

[Bob Dole]

Now let's see I just noted it's being sold at 20mg/ml aliquot vials so IF you weighed on 70kg you would require a whopping 3500 VIALS to reach the transgenic mice study 1g/kg dosage. Now why do you think those mice were SACRIFICED at the studies conclusion, LMAO!

My plan is 500mg every 7 days to see how that works.

 

[Dr JIM]

Of course another VALID concern would be how does this substance effect oxygen ON LOADING?

Does it remain attached to hemoglobin for "4-5" days and prevent the "on loading" of O-2 as the RBC reaches the lung?

If such was the case it would eventually result in a reduction of hemoglobins ability to bind O-2!

 

[Dr JIM]

My plan is 500mg every 7 days to see how that works.

It won't do squat based on the mice studies I just reviewed the dose they used STARTED at ONE GRAM/KG and reached a "plateau" at 2-3 gms/Kg

Good luck.

 

[Dr JIM]

I would also state on an unequivocal basis oral use of this PEP (and most others) is an absolute waste of money as degradation is essentially guaranteed upon exposure to stomach acid with an average PH of TWO!

 

[RobGreene]

ITPP is not a peptide. It can be taken orally. myo-Inositol Trispyrophosphate Hexasodium Salt | CAS 23103-35-7 | Santa Cruz Biotech

I can also attest to its efficacy orally.

 

[Dr JIM]

Yep it's not a PEP (but rather a pyrole salt) and can be orally ingested but your anecdotal evidence proves what exactly?

You won the Olympics bc of it, I know better, bc available evidence suggests this compound may improve exercise tolerance in those with cardiac dysfunction.

Just another supplement awaiting those willing to pay for its minimal "benefits" at best.

 

[heady muscle]

I would also state on an unequivocal basis oral use of this PEP (and most others) is an absolute waste of money as degradation is essentially guaranteed upon exposure to stomach acid with an average PH of TWO!

Is this the same with SARMS?

 

[RobGreene]

Anecdotes provide bayesian evidence. @heady muscle, no.

 

[Dr JIM]

Anecdotes provide bayesian evidence.

That's an oxymoron if there ever was one LMFAO!

Awaiting your next sales pitch!

 

[RobGreene]

So that's a good point. If your prior is that I'm trying to sell you something. Then the bayesian inference would tell you to disregard what I'm saying. If I have no obvious motivation for lying, it's fair to infer I'm telling the truth or at least that I believe what I say from which you can draw further inferences.

This is much less black magic than p<.05.

 

[Dr JIM]

Sorry but your anecdote of ONE is NOT EVIDENCE, but junk science that is a far cry from a "P value of 0.5" by any measure, except yours!

To that end if you want to attest to the efficacy of ITPP, post a human study exclusive of YOUR experience of ONE.

 

[RobGreene]

I totally agree with the need for clinical research. I just don't see the need for an emotional reaction every time someone says they had a good experience with X.