Corticosteroid Induced Adrenal Insufficiency

OldGHGuy

Member
Hey Meso,

I have a family member that just succeeded in defeating Stage 4 Lung Cancer that had spread to multiple areas of her body. Without getting into the amazing story of her battle and all that was involved, I will get right to the point of the post: she now has some very severe Adrenal Insufficiency due to all of the corticosteroids she used during her cancer treatment. In fact, the docs have told her now that she CAN'T stop the corticosteroids, or she will die. In the meantime, she is suffering from severe bloating from the corticosteroids (Cushings Syndrome) and her constant use has caused her adrenal insufficiency. It's one of these typical medical catch-22's: keep taking the steroids and die OR stop taking the steroids and die. Great choices.

She has tried to "wean" off slowly of the corticosteroids but always when she gets below a certain threshhold, she gets very sick. The weaning has been inneffective at getting her adrenals to start working again, too.

The endocrinologist doesn't seem to have any answers as far as getting her adrenals "jumpstarted" so I thought I would pose the question to Meso. Any ideas, pharma or otherwise?

@Type-IIx I know you have posted many times on the topic so I thought I would specifically include you just in case.
 
Last edited:
Hey Meso,

I have a family member that just succeeded in defeating Stage 4 Lung Cancer that had spread to multiple areas of her body. Without getting into the amazing story of her battle and all that was involved, I will get right to the point of the post: she now has some very severe Adrenal Insufficiency due to all of the corticosteroids she used during her cancer treatment. In fact, the docs have told her now that she CAN'T stop the corticosteroids, or she will die. In the meantime, she is suffering from severe bloating from the corticosteroids (Cushings Syndrome) and her constant use has caused her adrenal insufficiency. It's one of these typical medical catch-22's: keep taking the steroids and die OR stop taking the steroids and die. Great choices.

She has tried to "wean" off slowly of the corticosteroids but always when she gets below a certain threshhold, she gets very sick. The weaning has been inneffective at getting her adrenals to start working again, too.

The endocrinologist doesn't seem to have any answers as far as getting her adrenals "jumpstarted" so I thought I would pose the question to Meso. Any ideas, pharma or otherwise?

@Type-IIx I know you have posted many times on the topic so I thought I would specifically include you just in case.
Man, Cushings Syndrome is something for an endocrinologist. I actually sent a guy for cortisol labs recently with suspicions something was amiss, and they were insane. He was summarily diagnosed with it. I’m sorry she’s suffering brother, but she beat back cancer. That’s gangster!
 
Man, Cushings Syndrome is something for an endocrinologist. I actually sent a guy for cortisol labs recently with suspicions something was amiss, and they were insane. He was summarily diagnosed with it. I’m sorry she’s suffering brother, but she beat back cancer. That’s gangster!
Thank you brother. She's already a walking miracle but the fight's not over yet. She's going to a new endocrinologist next week so hopefully we can beat this too...

BTW - Don't sell yourself short. Most doctors I've experienced can't hold a candle to you
 

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