Kinda lengthy, but:
1. Pre-workout drinks without stim and stim have been tried (the former being dosed with nitric oxide and other stimulating compounds with the stim of caffeine and other herbal extracts) - compared to TNE kinda different, the TNE doesn't give a blood rushing kind of feeling in my chest. Several times, stim pre-workouts felt like my blood is rushing around my head, and like what Dirthand experienced, jittery feeling for period of time and then it felt like my heart was slowing down. Instead of my heartrate increasing and giving me the pump of "yeah, do this workout with the utmost strength and focus" I actually have mine slowing down when consuming caffeinated products of any kind, like it becomes a creeping feeling of anxiety rather than focus.
Only explanation for the decreased HR I saw that could possibly explain my case is this:
"Moderate doses of coffee have been shown to reduce resting heart rate due to a moderate increase in BP.[7,8] The decrease in heart rate is generally associated with vagally mediated slowing as the baroreceptors respond to BP elevations after caffeine administration. [1] Higher doses can produce heart rate acceleration, but such effects are not commonly associated with typical patterns of consumption." Cardiovascular Effects of Coffee: Is It a Risk Factor? - Page 3 ?form=fpf (locked behind a login requirement, kinda annoying)
TNE or no ester blends of any kind did give me a feeling a power, focus, and drive and sometimes powerlessness at the same time (dosage based, find the best and stick to it without the immediate sides), with the latter affecting performance, no improvement but still maintained strength.
2. I have tried TNE (100 mg/mL), TrNE (50 mg/mL), TNE + metribolone (5mg) (105mg/mL) and even a mix of the 2 at 50 mg/mL along with Metribolone at 5 mg/mL (105mg/mL) (so that's 4 different PWO vials, the 3rd and 4th being a blend mix and the latter being the one with the most painful after injection even with dilution).
3. If you workout everyday I would recommend taking breaks using it, like 5/4days on 2/3days off. If you are pushing for a PR or simply want to move the weights, use it. I use it MT-ThFriSat 0.5 mL before workout. (5 days/week, upper-lower x2, arms & shoulders), would decrease depending on my mood (like do I want to pin another one today).
4. Inject 30 mins to 1 hour before your workout. If you plan to use base blends (test + tren or test + metribolone) please eat something (rice,bread, some meat/fish and eggs) before exercising or you will feel hypo (happened twice, not a good experience, great I had maltodextrin powder sachet at hand). You got less than 3.5 hours. I generally take an AI (aromasin) after exercise.
5. Same as BamaCrazy, but it is temporary. Lightheadedness, spots in vision, dehydration (I do feel more dehydrated and consume 3L in a leg workout vs 2L in a leg workout w/o TNE, kinda subjective tho). Feel whether you can proceed or take meds for that (never experienced the point I cannot continue working out).
6. Regarding PIP: Only the 4th type did I experience this. I started at 0.2 mL diluted with 0.4 mL, still fucking painful if injected anywhere but the glutes. Only increasing it to 1:4 ratio (0.2 and 0.8 mL) Pain after injection lasts for 1 minute and you could feel it as you are moving but slowly fades away in less than 30 mins. Would not recommend injecting at the quads, I could feel the burning sensation crawl past my knees before fading like it was a nightmare. Carrier is not oil, the seller is using a Propylene glycol (MEG) base.
1st, 2nd, and 3rd types: no pain injecting, unless I mixed it with another oil suspension when I was rushing. Diluted with 1:0.2 ratio (0.5 mL of the compound + 0.1 mL MEG base). Currently using the 3rd type since it was the one I had a good experience with in terms of effect and injection, and I still have 3 whole vials left, gift from a friend.
The day after, the injection site will feel slightly sore, but if you did leg day it will be masked. Just inject in the Ass and properly follow sterilized injection protocols. Massage guns are your friend.
7. If using solo or a blend, always try the lowest you can go and go up from there, feel it while working out. Currently 50 mg TNE + 2.5 mg metribolone is great. Might try mixing TNE and TrNE 50 mg ea next time once my current blend is finished.
8. Regarding liver markers nothing changed much, just take your liver supplements religiously. Lastly, listen to your body.