Hunger is winning – Upping Reta or Adding Tirz?

[pewex]

Hey everyone,

I’m heading into week 13 of my cut, and it's starting to get really tough now that I'm down to mid single BF%. Up until now, I've been cruising on 5 mg of Reta a week, with barely any food noise or cravings. But over the last 2 weeks, the hunger and cravings have gone through the roof. I "crashed" last weekend and this one too.

I have 6 weeks of dieting left and my calories are pretty low.
I know it’s mostly a mental game for these last 6 weeks, but I want to make it as manageable as possible. So I'm thinking about either bumping up my Reta dose to 7.5 or 10 mg weekly, or maybe adding another GLP (I’ve got Tirz on hand) into the mix.

What do you guys think? Would upping the Reta or adding Tirz be better? I know the whole "just tough it out" mindset is ideal, but I’m struggling and I’m ready to increase the dose or stack if it’ll help.

My only concern is that I’m not exactly "obese" or overweight. I’m sitting at around 190 lbs and about true 7% BF, almost stage-ready.

Any input is appreciated!

 

[SpicyMeatball]

Add cagrilintide

 

[Ghoul]

Think of GLPs turning down the body fat / weight setting your body wants to maintain.

If you're above this setting, appetite suppression kicks in to bring you back down.

Below it, appetite stimulation occurs to drive you back up.

The further away you are from this "homeostasis" body fat / weight, the stronger the appetite suppression or stimulation will be.

An increased GLP dose turns the setting down lower.

Reta has a max dose of 12mg. I don't think it's necessary or advisable to add another compound since Reta has been working well for you, and you're no where near the max dose.

 

[MindlessWork]

OK what's the max dose for Semaglutide that can be safely used? If I read it correctly, isn't .25mg once a week a standard dose and can it be safely increased?

 

[pewex]

Add cagrilintide

Thanks for the suggestion. This is actually the first time I've heard about this compound, and after reading up on it, it sounds like it does exactly what I’m looking for and works synergistically with GLPs. The only problem is that my domestic sources don’t carry it, and ordering from CN (where I get my GLPs) would take 2-3 weeks. Still, I’ll definitely keep it in mind for the future.

Think of GLPs turning down the body fat / weight setting your body wants to maintain.

If you're above this setting, appetite suppression kicks in to bring you back down.

Below it, appetite stimulation occurs to drive you back up.

The further away you are from this "homeostasis" body fat / weight, the stronger the appetite suppression or stimulation will be.

An increased GLP dose turns the setting down lower.

Reta has a max dose of 12mg. I don't think it's necessary or advisable to add another compound since Reta has been working well for you, and you're no where near the max dose.

Thanks for the input!

You’re right, I have a feeling my body’s fighting back now that I’m so far from "homeostasis." I've cut down before, but this is my first prep where I'll be going on stage and my first time truly being mid singles BF%.

If I decide to up the Reta, do you think jumping to 7.5 mg from 5 mg is a good idea, or should I start with a smaller increase?

 

[pewex]

Another thing I’m worried about is when prep’s over I’ll probably eat myself sick if I drop the GLPs. So I need something for after prep is over as well in my back pocket.

I plan to rebound slow and steady, but let’s be real, we’re all human. I turn into a total cookie monster once carbs come back. Like today, I mentally crashed and ate 600g of carbs in one sitting, felt sick (but looked great) and was (I still am) burping acid all day!

The next few weeks are gonna be tough. Calories dropping even lower. Planning to do a PSMF for the last week or two to chase that Mike Mentzer level shredded look.

 

[Diixencider]

im at 5mg reta but i split that and pi 2x a week. reta has a half life of 5 days so the hunger suppression runs out fast and thats why i split my does which has worked incredibly well for me. i pin sunday night and thursday night

 

[pewex]

im at 5mg reta but i split that and pi 2x a week. reta has a half life of 5 days so the hunger suppression runs out fast and thats why i split my does which has worked incredibly well for me. i pin sunday night and thursday night

Thanks for the suggestion! I also split my doses but do it three times a week. I started splitting because I initially experienced acid reflux and an increased RHR. Once I began splitting the dose, those side effects subsided.

I mix a 10mg vial with 2ml of bacteriostatic water and inject 0.33ml on M-W-F. Since switching to this schedule, all side effects have gone away, and I’ve noticed the dosage seems to last longer compared to taking it once a week.

 

[Ghoul]

OK what's the max dose for Semaglutide that can be safely used? If I read it correctly, isn't .25mg once a week a standard dose and can it be safely increased?

Standard Sema pharma protocol is 4 weeks at each level of;

.25mg, .50mg, 1mg, 1.7mg, 2.4mg.

If weight loss and/or sides are still happening at any dose it can be extended until weight stops dropping or sides subside.

As far as "Safe" max dose. Doses up to 7.2mg have proven safe and effective in recent trials by Novo Nordisk and about to be FDA approved. Earlier studies showed doses up to 16mg, incredibly, are also safe, but with rapidly diminishing benefits.

There are only so many GLP receptors and once fully saturated there's no more weight loss or glucose control to be gained.

Sema has the most potent appetite suppression of the GLPs, works great, and a bargain compared to the others. But it's the only one imo that MUST be started at the minimum dose and titrated carefully, because too much too soon for the wrong person can cause some brutal sides. Not life threatening, just a really bad time for a few days.

Tirz and Reta can often be started at the 2nd level pharma dose (especially by men) without much risk of that happening by comparison,

If you feel ANY effects, don't increase until after the second shot of the same dose, then decide whether to increase the following week. It takes 2 doses to experience 80% of what that dose is capable of.

If you feel absolutely nothing, you might consider increasing to the next titration level on the next dose.

 

[Ghoul]

Thanks for the suggestion. This is actually the first time I've heard about this compound, and after reading up on it, it sounds like it does exactly what I’m looking for and works synergistically with GLPs. The only problem is that my domestic sources don’t carry it, and ordering from CN (where I get my GLPs) would take 2-3 weeks. Still, I’ll definitely keep it in mind for the future.
.
Thanks for the input!

You’re right, I have a feeling my body’s fighting back now that I’m so far from "homeostasis." I've cut down before, but this is my first prep where I'll be going on stage and my first time truly being mid singles BF%.

If I decide to up the Reta, do you think jumping to 7.5 mg from 5 mg is a good idea, or should I start with a smaller increase?

Eli Lily has settled on 2.4,8,12 as the titration doses in their trials. That tells us a jump from 4 to 8 is considered tolerable for everyone from large young men to little old ladies, so you can be confident 5 to 7.5 won't be an issue at all.

 

[pewex]

Eli Lily has settled on 2.4,8,12 as the titration doses in their trials. That tells us a jump from 4 to 8 is considered tolerable for everyone from large young men to little old ladies, so you can be confident 5 to 7.5 won't be an issue at all.

Thanks! I'll increase the dose to 7.5mg next week and see how it goes. Hopefully, the slight bump will help me avoid gluttoning out and if not next step is 10mg.

 

[Rotary1199]

Thanks! I'll increase the dose to 7.5mg next week and see how it goes. Hopefully, the slight bump will help me avoid gluttoning out and if not next step is 10mg.

Hey brother, I want to chip in for eoq testing but can’t contact you, can you dm me please

 

[pewex]

Hey brother, I want to chip in for eoq testing but can’t contact you, can you dm me please

Feel free to leave your email or Discord, and I'll reach out to you. Please keep the conversation within the relevant thread.

 

[BigDadd7]

Hey brother, I want to chip in for eoq testing but can’t contact you, can you dm me please

Classic scammer move

 

[Rotary1199]

Feel free to leave your email or Discord, and I'll reach out to you. Please keep the conversation within the relevant thread.

rotary11

 

[xrayphoton13]

I've run reta for a few months. Currently at 8mg. I've never noticed it do shit to my appetite unfortunately. I had XCE, then QSC. Both tested in testing groups fine. Everyone says sema is king of appetite suppression but for me it's tirzepatide. I came from 10mg tirzepatide so maybe that's why I'm disappointed by 8mg reta after two months but it feels like nothing to me. I don't feel like going up in dose due to cost so I actually went down to 6mg and threw in 2mg semaglutide. It definitely helped some but swapping semaglutide to 5mg tirzepatide was the magic ticket. No lethargy like higher dose tirz alone but now I'm feeling suppression again.

So this was just a long way of saying the answer will be individual to you.

 

[Ghoul]

I've run reta for a few months. Currently at 8mg. I've never noticed it do shit to my appetite unfortunately. I had XCE, then QSC. Both tested in testing groups fine. Everyone says sema is king of appetite suppression but for me it's tirzepatide. I came from 10mg tirzepatide so maybe that's why I'm disappointed by 8mg reta after two months but it feels like nothing to me. I don't feel like going up in dose due to cost so I actually went down to 6mg and threw in 2mg semaglutide. It definitely helped some but swapping semaglutide to 5mg tirzepatide was the magic ticket. No lethargy like higher dose tirz alone but now I'm feeling suppression again.

So this was just a long way of saying the answer will be individual to you.

I really question the trial results that show Reta results in greater weight loss, faster , than Tirz. The other possibility is UGL Reta differs in some way to what pharma is producing and less effective.

 

[pewex]

I've run reta for a few months. Currently at 8mg. I've never noticed it do shit to my appetite unfortunately. I had XCE, then QSC. Both tested in testing groups fine. Everyone says sema is king of appetite suppression but for me it's tirzepatide. I came from 10mg tirzepatide so maybe that's why I'm disappointed by 8mg reta after two months but it feels like nothing to me. I don't feel like going up in dose due to cost so I actually went down to 6mg and threw in 2mg semaglutide. It definitely helped some but swapping semaglutide to 5mg tirzepatide was the magic ticket. No lethargy like higher dose tirz alone but now I'm feeling suppression again.

So this was just a long way of saying the answer will be individual to you.

Did you notice any other benefits from Reta compared to Tirz/Sema? Like better morning blood glucose levels or anything else? What made you decide to stick with Reta?

Personally, I've tried Tirz and yeah it absolutely crushed my appetite. But I was still in a push phase and eating quite a bit, so I actually had to pull back even though I was only on a low dose (like 2-3mg, if I remember right).

I switched to Reta because of all the hype around improved insulin sensitivity and other benefits, but honestly, the only things I noticed were reduced food noise and a slight drop in appetite.

I think going forward, Reta will be something I use during the off season, while Tirz will be my go to for hunger control during cutting phases.

 

[xrayphoton13]

Did you notice any other benefits from Reta compared to Tirz/Sema? Like better morning blood glucose levels or anything else? What made you decide to stick with Reta?

Personally, I've tried Tirz and yeah it absolutely crushed my appetite. But I was still in a push phase and eating quite a bit, so I actually had to pull back even though I was only on a low dose (like 2-3mg, if I remember right).

I switched to Reta because of all the hype around improved insulin sensitivity and other benefits, but honestly, the only things I noticed were reduced food noise and a slight drop in appetite.

I think going forward, Reta will be something I use during the off season, while Tirz will be my go to for hunger control during cutting phases.

I'm just using it at this point due to how great people say it is, bc it doesn't make me tired, and bc I still have 4-5 vials. Once I run out I'll switch back to tirz for weight loss and sema for maintenance.
My blood glucose is great on it but it always has been. Only thing I can really contribute to it is the increase in RHR over even tirzepatide

 

[Naralol]

Have some self control man, you're already on reta