Chronic fatigue. What would you guys reccommend?

[Luke391]

I'm on tirz 10mg a week, methylene blue 5mg a day and a bunch of supplements.
I went from obese to healthy weight and I feel dead 24/7. Sleep is good and diet is very nutrient dense.
Training used to be great when I was fat, now it feels horrible, I wanna loose more fat but I'm plateaud because my activity level zero. I can get a bare minimim amount of lifting done but cardio or even 10k steps is out of the question. I even struggle with daily tasks due to low energy.
When I was obese I was way more active. I trained hard, I did 10-15k steps and did cardio consistantly (stairmaster/elliptical/rower). I was fat cause I ate like a garbage truck.
I'm not even lean, just normal looking, like 16-18%bf (I have abs a some muscle separation).

Would yall recommend me mithocondrial efficiency peptides? I got some carnitine on the way, would you say that will be enough to give me a boost or should I add something else?

idk if it's the tirz or the weightloss but I think the weightloss. I had lost weight naturally in the past and each time I felt tired af. I got on tirz because I wanna loose it once and for all this time.

 

[Bandern]

How long have you been in a deficit? I think diet breaks are over prescribed but you sound like a good candidate if you’ve spent significant time in a deficit and you’re struggling like that.

Put some food back in, drop fatigue, and maybe put on some size. You’ll wind up looking better when you start leaning out again.

 

[Ghoul]

Have you plateaued or still losing weight?

 

[Jaxino]

I'm on tirz 10mg a week, methylene blue 5mg a day and a bunch of supplements.
I went from obese to healthy weight and I feel dead 24/7. Sleep is good and diet is very nutrient dense.
Training used to be great when I was fat, now it feels horrible, I wanna loose more fat but I'm plateaud because my activity level zero. I can get a bare minimim amount of lifting done but cardio or even 10k steps is out of the question. I even struggle with daily tasks due to low energy.
When I was obese I was way more active. I trained hard, I did 10-15k steps and did cardio consistantly (stairmaster/elliptical/rower). I was fat cause I ate like a garbage truck.
I'm not even lean, just normal looking, like 16-18%bf (I have abs a some muscle separation).

Would yall recommend me mithocondrial efficiency peptides? I got some carnitine on the way, would you say that will be enough to give me a boost or should I add something else?

idk if it's the tirz or the weightloss but I think the weightloss. I had lost weight naturally in the past and each time I felt tired af. I got on tirz because I wanna loose it once and for all this time.

I would just take a week of break from diet and training.

 

[Luke391]

Have you plateaued or still losing weight?

I'm plateaud. on 10mg tirz I'm feeling no more appetite suppression than on 5mg, tho my activity level is very low. I am a bit worried about immunogenicity with tirzepatide. I have small filters on the way and I dilute to 1ml per dose

 

[Luke391]

How long have you been in a deficit? I think diet breaks are over prescribed but you sound like a good candidate if you’ve spent significant time in a deficit and you’re struggling like that.

Put some food back in, drop fatigue, and maybe put on some size. You’ll wind up looking better when you start leaning out again.

I was in a deficit for 3 months and then I've been plateaud for about 2 months because my activity level is super low so I can't sustain the deficit with just less food.
Not that my calories are super low, I'm at 2600-2800. but I'm doing zero cardio and maybe 2-4k steps per day because I have no energy.

 

[sliderke]

Lower the tirz dose back to basic 2,5 mg and make sure you eat more.
When you’re not taking in enough calories you don’t have energy. It’s not rocket science.

 

[BamaCrazy]

I’d rest from training for a week and increase caloric intake.

As far as peptides, look at MOTS-c, Cardarine, GH and 5-Amino-1MQ.

 

[Luke391]

Lower the tirz dose back to basic 2,5 mg and make sure you eat more.
When you’re not taking in enough calories you don’t have energy. It’s not rocket science.

I really would rather not lower the tirz dose. If I do I will 100% regain the weight. initially I felt nothing on 2.5mg and then it suppressed my appetite a lot on 5mg. it faded as I lost weight and I'm not at 10mg to look to keep loosing, but my calories aren't very low, I'm at 2600-2800

 

[Bandern]

I was in a deficit for 3 months and then I've been plateaud for about 2 months because my activity level is super low so I can't sustain the deficit with just less food.
Not that my calories are super low, I'm at 2600-2800. but I'm doing zero cardio and maybe 2-4k steps per day because I have no energy.

So 5 months total in a deficit? 2 month plateau is no bueno. You need a reset.

My first push from being a fatass I dropped 50lbs in about 6 months. I got to what is technically a healthy bf % but I looked like a melted bag of trash. I had to bulk and cut a few times to actually look good when I got leaner.

If you truly went from being obese to “normal looking”, then that’s incredible progress. Allow yourself a break. Enjoy eating a little more food, just keep it clean and don’t be an idiot. Keep training hard and progressing your lifts. You’ll be in a better spot when you start leaning out again in a few months.

 

[Musmadar]

Try to take some iron for a few days .... Just to see it it let's better.

 

[Ghoul]

What you're describing is common after any significant weight loss. .

Since you're not in a deficit any number big things could be the cause, but a change in hormone levels is very likely and easy to check.

Thyroid can down regulate a lot when there's major weight loss, and it's easy to slip into hypothyroidism or sub-clinical hypothyroidism.

It's worth checking, fairly easy to address with T4, and the change in energy levels can be dramatic once thyroid hormones are optimized. I'd start with something like ultalabtests.com and get a quick basic thyroid panel, then take it from there. Ideally you want to be in the 75-80th percentile of Free T4 for your age.

 

[Luke391]

What you're describing is common after any significant weight loss. .

Since you're not in a deficit any number big things could be the cause, but a change in hormone levels is very likely and easy to check.

Thyroid can down regulate a lot when there's major weight loss, and it's easy to slip into hypothyroidism or sub-clinical hypothyroidism.

It's worth checking, fairly easy to address with T4, and the change in energy levels can be dramatic once thyroid hormones are optimized. I'd start with something like ultalabtests.com and get a quick basic thyroid panel, then take it from there. Ideally you want to be in the 75-80th percentile of Free T4 for your age.

I didn't think about checking my thyroid, thanks. When I was a kid/teen I was put on thyroid meds for some time but at 16/17 I think the doctor had me stop, idk why. I will look into that, thank you

 

[Ghoul]

I didn't think about checking my thyroid, thanks. When I was a kid/teen I was put on thyroid meds for some time but at 16/17 I think the doctor had me stop, idk why. I will look into that, thank you

Optimizing thyroid with 100mcg Thyroxine (T4) from 25th percentile to 75th boosted my energy a TON after dropping 40lbs. No exaggeration to call it damn near life altering, and brand name pharma, Abbot labs, is less than $5 for 4 months worth.

Brain fog cleared...appetite dropped and ended up inadvertently losing another 10 lbs in a couple of weeks.

 

[Luke391]

Optimizing thyroid with 100mcg Thyroxine (T4) from 25th percentile to 75th boosted my energy a TON after dropping 40lbs. No exaggeration to call it damn near life altering, and brand name pharma, Abbot labs, is less than $5 for 4 months worth.

Brain fog cleared...appetite dropped and ended up inadvertently losing another 10 lbs in a couple of weeks.

sounds amazing. where did you get the T4 from? do you have a prescription or does anyone on here sell pharma thyroid hormones?

 

[buck]

Post your stats.
Diet
Workout.

 

[Ghoul]

sounds amazing. where did you get the T4 from? do you have a prescription or does anyone on here sell pharma thyroid hormones?

India PCT sellers sell it at all doses.

Be sure to start with and stick to a reputable brand. Variations in potency between batches, or switching brands once you have the right dose dialed in can lead to very inconsistent results.

Abbot, the original developer of synthetic T4 is the largest manufacturer of it in the world, and known for remaining consistant over decades.

If you want to get a head start, since it's cheap enough and will take a few weeks to arrive, you could order a couple of bottles (120tabs) each of 25mcg and 50mcg.

Typical starting dose is 1.6mcg/kg, 150mcg for 200lbs. But the conservative approach is to start with 50mcg, and titrate up after a month by 25-50mcg, and repeat until you hit the numbers on testing and/or feel better, without going supra-physiological.

You should notice the type of improvement you can expect within the first week of 50mcg. Even if that turns out to be insufficient, as it likely will, it takes a while for endogenous production to downregulate, so it's an immediate, if temporary boost to Free T4. It takes about 6 weeks for a given dose to stabilize.

Had I started using the guideline 150 (I had low but normal range Free T4) it would've been way too much for me.

"Thyroid optimization clinics", especially in the context of anti-aging, have been following the trajectory TRT has over the last decade.

 

[Demondosage]

First place I’d look at is a nutrient deficiency, such as if the diet is too carb starved or not enough healthy fats (whichever is lacking add back in) and if that doesn’t fix it I would get my thyroid tested, maybe change the workout routine to less weights and more cardio

 

[Luke391]

First place I’d look at is a nutrient deficiency, such as if the diet is too carb starved or not enough healthy fats (whichever is lacking add back in) and if that doesn’t fix it I would get my thyroid tested, maybe change the workout routine to less weights and more cardio

I'll get my thyroid checked and lower volume and try to add a bit of cardio back in, thanks.
I doubts it's a nutrient deficency since I put a lot of tought into making sure every micronutrient intake is covered.I take supplements for what I don't get trough diet (omega 3, vitamin d3, k2, and so on)

 

[DugPrime]

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