HGH 40 +

[eryximachus]

GH is the one thing that will change how your body looks like nothing else. Especially when the doses get up around 8-10iu or more.

What have you experienced over what time period?

 

[lilhawk]

I’d agree though those dosages take time to acclimate / build up to and often do come with some side effects whether it be CTS / water retention, insulin resistance, lethargy, etc.

Also, I believe it was readalot who posted an article studying the impact of supraphysiological HGH doses, and 0.03 mg / kg was the upper limit where cardiac changes did not occur. That translates into 9 iu a day for a 100 kg person. So if you’re under 220 lbs and taking more than 9 iu daily you’re playing with fire in that regard.

Chase Irons likes to talk about how he had a cardiac MRI after his 18 iu / day Serostim experiment and per his report there were no changes. I’d like to see a repeat study in 5-10 years along with an echocardiogram. It reminds me of the man who jumped from a 100 story building and when he got past the 30th floor he yelled out “so far so good!”

8-10 iu is where I think the best dose is for me, I won’t go above that, and unless dieting hard I usually stay at 6iu. I’m around 235-240 right now dieting hard for the last 2 months. I’ve never had a cardiac MRI, but have had echos’s, EKGs, etc and everything is normal. I only ever use Serostim and have been for a decade, with breaks here and there. Only recently started upping the dose and it definitely makes a difference. I will always use Reta as it keeps my BG perfect no matter the GH dose.

 

[Ghoul]

. I’d like to see a repeat study in 5-10 years along with an echocardiogram. It reminds me of the man who jumped from a 100 story building and when he got past the 30th floor he yelled out “so far so good!”

That's what I think of when I hear "I haven't ever (fill in the precaution) and don't have any issues".

Back when they were still using cadaver based hgh, they found out that deformed CJD proteins only started causing symptoms 5 to 30 YEARS after injecting.

Randomly formed protein aggregates from UGL peptides or rHGH can accumulate and linger in tissues for years, or forever in some cases, with absolutely no idea of their long term effects.

 

[RockyP]

8-10 iu is where I think the best dose is for me, I won’t go above that, and unless dieting hard I usually stay at 6iu. I’m around 235-240 right now dieting hard for the last 2 months. I’ve never had a cardiac MRI, but have had echos’s, EKGs, etc and everything is normal. I only ever use Serostim and have been for a decade, with breaks here and there. Only recently started upping the dose and it definitely makes a difference. I will always use Reta as it keeps my BG perfect no matter the GH dose.

Sounds like a very well thought out plan - Chase was running 18+ iu Serostim for a year I think prior to that cardiac MRI - i don't think it's necessary for most of the people on the planet using HGH. Per that study (see attached - originally shared by another member so don't give me the credit), 9 iu (0.03 mg / kg) was the max dose for a 100 kg person where changes in cardiac morphology / function were not observed. I too plan to ramp up as high as I can tolerate. I'm about the same weight as you and currently just went from 3 to 4 iu at bedtime - have blood work coming next week and if all is well, will likely add 2 iu in the AM (or maybe just go to 6 at bedtime idk). Prior to my 15 year hiatus from PEDs, I ran 4 to 6 iu daily of Jintropin and 6 iu of UGL blue tops daily with really great results, though i was in my 20's and blasting a good amount of gear. I'm looking mostly for recovery, sleep, fat loss, and longevity. That said, for us 100+ kg folks I do think 6 iu daily and above is where the magic happens.

Supraphysiological doses of GH induce rapid changes in cardiac morphology and function - PubMed

GH is an agent widely used in sport to improve physical performance and has been proposed as adjunctive therapy in several clinical conditions. However, its short-term effects on the normal human heart are poorly understood. Sixty young normal volunteers (30 males and 30 females) were enrolled...

pubmed.ncbi.nlm.nih.gov

 

[Mick]

I have a question for you guys. So I have been running 2 iu am and 2 iu pm. I am in really good visible shape. 6ft. 195-205. Around 10percent I would say. I have been checking my “fasted” blood sugar. Ussually I wake up. Get a glass of water. Let the dog out. Then take it like that. I would say maybe 15 min after actually waking. It is ussually some where between 79-85. This morning I did something diff and it went as followed. I woke up and took it within like 2min of waking. It was 110!!! I retested in 5min. It was 101. Then I waited about 15 more min and it was 79. Is this a normal am spike?? Is this why I wake up with anxiety?? lol. I wake up with an alarm that slowly lights like the sun idk if that attributes. Basically it scared me, I never seen a number that high fasted. Nowhere near.

 

[roofer22]

I'm 51 been on for a couple years now except a couple months off after my insulin sensitivity went to shit on 9iu. For the last several months I've been running 4.

 

[Ghoul]

I have a question for you guys. So I have been running 2 iu am and 2 iu pm. I am in really good visible shape. 6ft. 195-205. Around 10percent I would say. I have been checking my “fasted” blood sugar. Ussually I wake up. Get a glass of water. Let the dog out. Then take it like that. I would say maybe 15 min after actually waking. It is ussually some where between 79-85. This morning I did something diff and it went as followed. I woke up and took it within like 2min of waking. It was 110!!! I retested in 5min. It was 101. Then I waited about 15 more min and it was 79. Is this a normal am spike?? Is this why I wake up with anxiety?? lol. I wake up with an alarm that slowly lights like the sun idk if that attributes. Basically it scared me, I never seen a number that high fasted. Nowhere near.

It's the normal pattern for GH induced insulin resistance. Consider adding Reta or Tirz to your protocol to protect your beta cells. The longer 100+ fasted morning glucose goes on, the more your risk of developing diabetes (now or years in the future, even off GH) increases.

 

[Mick]

It's the normal pattern for GH induced insulin resistance. Consider adding Reta or Tirz to your protocol to protect your beta cells. The longer 100+ fasted morning glucose goes on, the more your risk of developing diabetes (now or years in the future, even off GH) increases.

I have been looking into Reta a lot. Problem is I feel like I won’t eat at all on a drug like that. I have a hard time getting my meals in as it is. Appetite has never been my thing. But when are you suppose to prick yourself for fasted glucose. Like as soon as I get out of bed. Or 15 or 20 min later. Because I have been thinking my fasting glucose is low 80s. But that’s 20 min after waking. 1 min after waking is totally diff number? I’m going to monitor before and after meals and all that see what’s actually going on. As far as Reta I’m def thinking about trying a very very low dose eod just for the health benefits

 

[Mick]

Honestly this whole ped thing after a certain point can become a real pain in the ass. Checking bp. Checking blood sugar. My morning protocol looks like a hospital stay lmfao

 

[AlexDavis43]

I have been looking into Reta a lot. Problem is I feel like I won’t eat at all on a drug like that. I have a hard time getting my meals in as it is. Appetite has never been my thing. But when are you suppose to prick yourself for fasted glucose. Like as soon as I get out of bed. Or 15 or 20 min later. Because I have been thinking my fasting glucose is low 80s. But that’s 20 min after waking. 1 min after waking is totally diff number? I’m going to monitor before and after meals and all that see what’s actually going on. As far as Reta I’m def thinking about trying a very very low dose eod just for the health benefits

The normal pattern for GH-induced insulin resistance?

I don't know if that's just plain misinformation or maybe a poorly prompted ChatGPT reply.

Anyway, just measure FBG again at the same time a few more days. The actual time doesn't matter much.

If it's consistently 110+ then the next conversation is how much do you like running GH? Enough to need other drugs to treat the side effects of GH?

No need to bring a GLP1 on board until you have established consistently elevated FBG, in which case that's not your only option.

 

[Mick]

The normal pattern for GH-induced insulin resistance?

I don't know if that's just plain misinformation or maybe a poorly prompted ChatGPT reply.

Anyway, just measure FBG again at the same time a few more days. The actual time doesn't matter much.

If it's consistently 110+ then the next conversation is how much do you like running GH? Enough to need other drugs to treat the side effects of GH?

No need to bring a GLP1 on board until you have established consistently elevated FBG, in which case that's not your only option.

I meant what is the normal time to measure fbg. Because my results vary greatly from literally waking up to my alarm and testing within 2 min of waking. Vs checking 15min after waking. This morning from 110 to 79. I’ll check again tomorrow but it seems as if my body is using a blood sugar spike to wake me up. I also ate sugar before bed last night. That is way out of the norm for me but I don’t think that should matter. I could care less about the gh. But I’m going to make sure I’m measuring right before I drop it.

 

[AlexDavis43]

I meant what is the normal time to measure fbg. Because my results vary greatly from literally waking up to my alarm and testing within 2 min of waking. Vs checking 15min after waking. This morning from 110 to 79. I’ll check again tomorrow but it seems as if my body is using a blood sugar spike to wake me up. I also ate sugar before bed last night. That is way out of the norm for me but I don’t think that should matter. I could care less about the gh. But I’m going to make sure I’m measuring right before I drop it.

Fasting blood glucose in the morning shouldn't be over 100 regardless if it's 2 minutes or 15 minutes after waking up

Keep measuring it for a few more days to make sure it isn't a weird acute anomaly or something

 

[Ghoul]

I have been looking into Reta a lot. Problem is I feel like I won’t eat at all on a drug like that. I have a hard time getting my meals in as it is. Appetite has never been my thing. But when are you suppose to prick yourself for fasted glucose. Like as soon as I get out of bed. Or 15 or 20 min later. Because I have been thinking my fasting glucose is low 80s. But that’s 20 min after waking. 1 min after waking is totally diff number? I’m going to monitor before and after meals and all that see what’s actually going on. As far as Reta I’m def thinking about trying a very very low dose eod just for the health benefits

It's fasting glucose at any point 8 hours after last eating.

Low dose reta has the best reputation for not inducing appetite suppression while improving insulin sensitivity. Most people have to titrate it up to a certain point before getting suppression. Not everyone, some are very sensitive, but can't hurt to try .5mg / week which is unlikely to reduce your appetite and will still boost sensitivity intensity.

 

[RockyP]

Honestly this whole ped thing after a certain point can become a real pain in the ass. Checking bp. Checking blood sugar. My morning protocol looks like a hospital stay lmfao

assuming you run intelligent / low dosages and don’t keep pushing when you see aberrant lab values or vital signs, I actually think that PED users have a much greater handle on their health than 99% of the population. The whole issue of course is what do you do with the information?

 

[aliikamz]

Just curious, how many of us 40 + y/o are running HGH.
If so, at what dose and for how long ?

Turned 42 this year. Started at 2iu 7 months ago and gradually increased to 8iu now. Daily. I do it all in the AM for convenience.

Tbh, I feel like it does help but Im also on 250mg test e, 6mg reta, 10mg MOTS-C, and 10mg GLO weekly. So I cant really isolate which does which. Size is still decent. Wouldn't say I was jacked but it keeps my weight under control. Bloods are good. Workouts and recovery is fine.

 

[Mick]

assuming you run intelligent / low dosages and don’t keep pushing when you see aberrant lab values or vital signs, I actually think that PED users have a much greater handle on their health than 99% of the population. The whole issue of course is what do you do with the information?

Your right. It was a joke. More like the more I learn the more I’m checking shit. I also believe at a certain point checking to much shit and obsessing about it is negative to health as well. It’s a fine line. Also most ppl who run intelligent doses at one point did not. I’m sure there is some exceptions. But I wasn’t one lol.

 

[bigdaddyandfriends]

I’d agree though those dosages take time to acclimate / build up to and often do come with some side effects whether it be CTS / water retention, insulin resistance, lethargy, etc.

Also, I believe it was readalot who posted an article studying the impact of supraphysiological HGH doses, and 0.03 mg / kg was the upper limit where cardiac changes did not occur. That translates into 9 iu a day for a 100 kg person. So if you’re under 220 lbs and taking more than 9 iu daily you’re playing with fire in that regard.

Chase Irons likes to talk about how he had a cardiac MRI after his 18 iu / day Serostim experiment and per his report there were no changes. I’d like to see a repeat study in 5-10 years along with an echocardiogram. It reminds me of the man who jumped from a 100 story building and when he got past the 30th floor he yelled out “so far so good!”

I've capped my dose at 7.5iu/day for this reason. Just turned 57 yo, about 95kg.

 

[RockyP]

Your right. It was a joke. More like the more I learn the more I’m checking shit. I also believe at a certain point checking to much shit and obsessing about it is negative to health as well. It’s a fine line. Also most ppl who run intelligent doses at one point did not. I’m sure there is some exceptions. But I wasn’t one lol.

Agreed. Imy gear use in my 20’s was idiotic. Now my health is number 1 and I’m very careful and methodical. For me that means no orals and total weekly doses under 500 mg. I also agree about obsessing. BP levels can fluctuate for various reasons. But if I add in say deca and the numbers stay elevated all week then I know I have an issue. There’s always a sweet spot in there

 

[Mick]

Fasting blood glucose in the morning shouldn't be over 100 regardless if it's 2 minutes or 15 minutes after waking up

Keep measuring it for a few more days to make sure it isn't a weird acute anomaly or something

I will. I’m going to check about 5 min after waking. One of my points is that if I continued my normal routine this morning I would have checked fasted. About 15 min after waking and saw 79. And think I’m fine. When actually if I checked 10 min before that I’m high. That’s important or I wouldn’t have any idea. Also no one has answered is a spike in glucose what wakes ppl up? Something with that along with cortisol. I’m going to check for the next 7 days. Keeping gh the same. If it’s high I’ll just drop it for a while. Or try one 2iu dose either am or pm I appreciate the answers guys. Thanks

 

[Mick]

Agreed. Imy gear use in my 20’s was idiotic. Now my health is number 1 and I’m very careful and methodical. For me that means no orals and total weekly doses under 500 mg. I also agree about obsessing. BP levels can fluctuate for various reasons. But if I add in say deca and the numbers stay elevated all week then I know I have an issue. There’s always a sweet spot in there

Exactly. I struggle with that balance in my entire life. I swear that balance is the definition of health lol. And of course being preventative etc