SubQ vs IM injection

Thanks for the info. I only started using test, so scar tissue hasn’t been a concern. Unfortunately I don’t think the subq injections are agreeing with me. 24 hours after injection the site swells up and is a little tender for a few days. I’ve done 4 low dose injections, .33ml test 250, same result. I used a 30 gauge 1/2 insulin pins.

Yesterday I did an Im injection in my delt and have had no issues. If this holds I might be switching over? I used a 25 gauge 1 inch pin injecting same dose.
Usually delta are the way to go, rotate them… i do sub q into stomach fat and rarely have an issue
 
Usually delta are the way to go, rotate them… i do sub q into stomach fat and rarely have an issue
I did a few Im injections in my delts and had zero issues, no inflammation or anything. Went back to doing subq in stomach, and ass, and the inflammation is hit and miss. I even added another injection day, 1/3ml Monday, Wednesday, and Friday. The issues Arent bad enough to lose sleep over but enough to contemplate switching to im injections permanently.
 
I tried Sub Q, the result is hard sometimes painful lumps that last for at least a week, even with small 0.1-0.25mL injections.

I made the mistake of trying Tren A sub q in the stomach fat, that lump took 3 weeks to go away and hurt the whole time.

Fuck sub q for oil based injections.
 
I did a few Im injections in my delts and had zero issues, no inflammation or anything. Went back to doing subq in stomach, and ass, and the inflammation is hit and miss. I even added another injection day, 1/3ml Monday, Wednesday, and Friday. The issues Arent bad enough to lose sleep over but enough to contemplate switching to im injections permanently.

How do you tell if u got inflammation? What are the signs and symptoms?
 
How do you tell if u got inflammation? What are the signs and symptoms?
For me, the subq, 30 gauge 1/2 inch, injection site swells up and is red and itchy. Almost like an allergic reaction. Fairly certain it’s an immune response similar to welts from bug bites. The site then gets sore for a few days, not horribly painful but tender. Think tender like a bruised spot. The symptoms dissipate within 5 days to a week.

When I did the Im injections, a couple in the delts and one in the glute, 25 gauge 1 inch needle, there were no symptoms at all. No itching, soreness, nothing. Call me crazy, and maybe it is mental, but I seem to feel the test kicking in. Subq is so gradual I don’t notice any onset.

Im not advocating one way or another. I wanted to do subq because I have the needles and read reports claiming it is better/more stable. Thats kind of why I’m sticking to that injection style even though Im doesn’t give me the same issues.

All this is new to me so don’t read into it too much. Hell maybe a have a slight allergy to the carrier oil? Just sharing my experience to help others and learning from those with more experience.
 
All this is new to me so don’t read into it too much. Hell maybe a have a slight allergy to the carrier oil?
I was actually to ask if you tried another carrier or ester while reading through the thread.

I haven't been doing this long at all but subQ in the glute for me is vitrtually painless and zero PIP, inflammation, or irritation at all. I know everyone is different and all, but I do wonder if it's a carrier or ester, or if your body just isn't a fan.
 
I was actually to ask if you tried another carrier or ester while reading through the thread.

I haven't been doing this long at all but subQ in the glute for me is vitrtually painless and zero PIP, inflammation, or irritation at all. I know everyone is different and all, but I do wonder if it's a carrier or ester, or if your body just isn't a fan.
I’ve been using mct test c 250. I honestly dont have enough experience to say there is a definitive issue. My initial thought was if I was allergic to the oil, wouldn’t I have some symptom with an im injection to? Maybe someone else that stumbles into the thread can educate us?
 
My initial thought was if I was allergic to the oil, wouldn’t I have some symptom with an im injection to? Maybe someone else that stumbles into the thread can educate us?
I would think you'd feel something IM if you were, but I don't know enough about how the body works to know if both sites would be handled the same way from a response perspective. Depending on the source, perhaps there could be something in the test that is causing mild irritation, but not enough at IM levels to notice maybe?

I have only ever had a response like that with GHK-Cu and chucked the vial before I knew it was prone it PIP. Same symptoms you described to a T, FWIW.
 
PIP. Same symptoms you described to a T, FWIW
I was curious about that. I heard test c 250 was borderline for pip in people sensitive. I’m not ruling anything out. At some point I’ll try another batch or a lower mg/ml dose and see if I have the same results. It’s like anything else in life, get through the learning curve and see what’s what.
 
I tried Sub Q, the result is hard sometimes painful lumps that last for at least a week, even with small 0.1-0.25mL injections.

I made the mistake of trying Tren A sub q in the stomach fat, that lump took 3 weeks to go away and hurt the whole time.

Fuck sub q for oil based injections.

Damn, that's bad luck. In my previous cycle i was pinning 0,3ml of Tren Ace everyday subc in my glutes/hips and had zero lumps or discomfort. Some guys handle it, some not. Obviously if your body doesn't like it there's no reason to force it.
 
I was initially going to utilize IM injections for my self prescribed TRT. I then saw people referencing a study that showed SubQ injections were more beneficial. Higher test levels, lower estradiol and hematocrit levels. After seeing this, and having a couple hundred insulin needles, I decided to go the SubQ route. Just for reference…my first time with peds, using test c 250, starting low with 1/4 ml Monday/Thursday to see how I handle it for a few weeks then bumping to 1/2 ml twice a week

I understand I can inject a higher volume with an IM injection, but I’m not at that point. Am I missing anything that should factor in to the equation? Also curious if I can inject deca the same way when I get to that stage. Thanks in advance
SubQ with low doses of test c works fine – often gives more stable levels, sometimes lower E2 and HCT. Downside is that larger volumes can cause lumps or irritation, so for bigger doses IM is better. For deca it’s usually recommended IM, since it’s more oil and can be uncomfortable SubQ.
 
I envy all of you that can do subq. I just get a gigantic rash and literally crashed hormone levels. I've tried so many times throughout the years and it just doesn't do shit.

3x3month runs with barely in-range TT at 150-250mg/w (dose devided to MWF) TE/TC. I've tried MCT, GSO and sesame as carriers, a few other compounds like EQ Deca or Tren A and never got much of an effect. 1 whole ML of tested Tren ace EOD did get me slightly irritable but that's about it, about 70mg/w does that for me. Also some 4-8w runs but I just gave up on it.

I understand the hormones have to go somewhere once injected, but I had barely 80yo levels of test at the same doses that get me to ~900-2000 IM.

I might aswell just do oils sublingually... I'm just tired of even trying to get it to work, I'd rather lose mobility for martial arts but have my weewee work...

Now I just gotta find a source with castor oil so I don't feel like a pin cushin this much, my body runs through MCT depots, which happen to be the most common for UGLs within a day or 2 at the very most.
 
My apologies…it was a generalized you, to anyone reading, and not specifically directed at “you”. There are some who discount anything that comes from YouTube personalities.

I can’t see or think of a valid reason he would misrepresent that type of info/data.

I'm more inclined to trust the medical literature with carefully gathered pharmacokinetic data than some YouTube bro...

Read the following and tell me whether you think there's a 6 week difference (assuming ~6wks to stable concentration with Enan/Cyp)

Code:
Kaminetsky, J., Jaffe, J. S., & Swerdloff, R. S. (2020).
Pharmacokinetic profile of subcutaneous testosterone enanthate delivered via a novel, prefilled single-use autoinjector: a phase II study. Sexual Medicine, 8(2), 269–279.

Lopez, D. S., et al. (2022).
Pharmacokinetics of subcutaneous versus intramuscular testosterone undecanoate in transgender men. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1636–e1645.

Olson, D. W., et al. (2022).
Subcutaneous Testosterone: A Review of the Literature and an Analysis of the Classic Formula in the Modern World. Sexual Medicine Reviews, 10(2), 333-343.

Al-Futaisi, A. M., Al-Zakwani, I. S., Al-Mahrezi, A. M., & Morris, D. (2009).
Subcutaneous administration of testosterone. A pilot study report.
 
I'm more inclined to trust the medical literature with carefully gathered pharmacokinetic data than some YouTube bro...

Read the following and tell me whether you think there's a 6 week difference (assuming ~6wks to stable concentration with Enan/Cyp)

Code:
Kaminetsky, J., Jaffe, J. S., & Swerdloff, R. S. (2020).
Pharmacokinetic profile of subcutaneous testosterone enanthate delivered via a novel, prefilled single-use autoinjector: a phase II study. Sexual Medicine, 8(2), 269–279.

Lopez, D. S., et al. (2022).
Pharmacokinetics of subcutaneous versus intramuscular testosterone undecanoate in transgender men. The Journal of Clinical Endocrinology & Metabolism, 107(4), e1636–e1645.

Olson, D. W., et al. (2022).
Subcutaneous Testosterone: A Review of the Literature and an Analysis of the Classic Formula in the Modern World. Sexual Medicine Reviews, 10(2), 333-343.

Al-Futaisi, A. M., Al-Zakwani, I. S., Al-Mahrezi, A. M., & Morris, D. (2009).
Subcutaneous administration of testosterone. A pilot study report.

Im going to level with you..it doesn’t matter to me enough to debate this. I’m not going to read through every one of those studies and every critique of each of those studies to formulate an opinion on something that has no practical benefit to me.

While I agree that many in social media make outlandish claims “for clicks”. I watched the vigorous Steve video in question myself. He references his own bloodwork and subq injection process. My only point is it seems plausible. If he’s fabricating bloodwork results or faking the injection protocol over an issue so trivial, shame on him.

The stabilization time frame is not that important to what I’m doing personally. To someone else it may, so thank you for posting the studies. It’ll give anyone interested a good starting point for their own research. Perhaps if I was running a cycle, or working in a limited window, it would be a more pressing issue.

My honest opinion...If one is worried 6 weeks is not sufficient time for stabilization, and they aren’t experiencing negative sides, wait a few more weeks to have levels checked. I typically err on the side of caution so it seems prudent to allow additional time.
 
Im going to level with you..it doesn’t matter to me enough to debate this. I’m not going to read through every one of those studies and every critique of each of those studies to formulate an opinion on something that has no practical benefit to me.

While I agree that many in social media make outlandish claims “for clicks”. I watched the vigorous Steve video in question myself. He references his own bloodwork and subq injection process. My only point is it seems plausible. If he’s fabricating bloodwork results or faking the injection protocol over an issue so trivial, shame on him.

The stabilization time frame is not that important to what I’m doing personally. To someone else it may, so thank you for posting the studies. It’ll give anyone interested a good starting point for their own research. Perhaps if I was running a cycle, or working in a limited window, it would be a more pressing issue.

My honest opinion...If one is worried 6 weeks is not sufficient time for stabilization, and they aren’t experiencing negative sides, wait a few more weeks to have levels checked. I typically err on the side of caution so it seems prudent to allow additional time.
I’m having high E sides already so will do bloodwork next week (will be 4th week ON), no point delaying it I think!

Thanks for the input though.
 
I’m having high E sides already so will do bloodwork next week (will be 4th week ON), no point delaying it I think!

Thanks for the input though.
Definitely go if you’re already having issues. Only you know how you feel and always be cautious with your health. Not sure what a your administering protocol looks like, but if you continue the treatment, maybe try lower doses and more frequent injections.
I’m in my fourth week now but During my second week my nipples were more sensitive and erect. It lasted for a couple days but everything settled back down. I just chalked it up to hormone fluctuations.
 
Damn, that's bad luck. In my previous cycle i was pinning 0,3ml of Tren Ace everyday subc in my glutes/hips and had zero lumps or discomfort. Some guys handle it, some not. Obviously if your body doesn't like it there's no reason to force it.
Sorry to bump an older thread, did you (or anyone else) notice you experienced less tren cough from subq vs im? Or were the chances of it happening pretty much equal in both?
 
Sorry to bump an older thread, did you (or anyone else) notice you experienced less tren cough from subq vs im? Or were the chances of it happening pretty much equal in both?

I've never had a single tren cough with subc. I can't tell for sure if it was random or not.

There were 2-3 times i saw some drops of blood after pulling the syringe out from hitting a blood vessel, since they re in the skin surface and i was expecting to experience it but thankfully never happened lol.
 
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